| Critical Assessment of Metagenome Interpretation: the second round of challenges F Meyer, A Fritz, ZL Deng, D Koslicki, TR Lesker, A Gurevich, G Robertson, ... Nature methods 19 (4), 429-440, 2022 | 249 | 2022 |
| Genome streamlining and chemical defense in a coral reef symbiosis JC Kwan, MS Donia, AW Han, E Hirose, MG Haygood, EW Schmidt Proceedings of the National Academy of Sciences 109 (50), 20655-20660, 2012 | 174 | 2012 |
| Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor Y Liu, LA Salvador, S Byeon, Y Ying, JC Kwan, BK Law, J Hong, ... Journal of Pharmacology and Experimental Therapeutics 335 (2), 351-361, 2010 | 149 | 2010 |
| Lyngbyoic acid, a “tagged” fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa JC Kwan, T Meickle, D Ladwa, M Teplitski, V Paul, H Luesch Molecular bioSystems 7 (4), 1205-1216, 2011 | 128 | 2011 |
| Grassystatins A− C from Marine Cyanobacteria, Potent Cathepsin E Inhibitors That Reduce Antigen Presentation JC Kwan, EA Eksioglu, C Liu, VJ Paul, H Luesch Journal of medicinal chemistry 52 (18), 5732-5747, 2009 | 116 | 2009 |
| An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles LV Flórez, K Scherlach, IJ Miller, A Rodrigues, JC Kwan, C Hertweck, ... Nature communications 9 (1), 1-10, 2018 | 114 | 2018 |
| Species specificity of symbiosis and secondary metabolism in ascidians MDB Tianero, JC Kwan, TP Wyche, AP Presson, M Koch, LR Barrows, ... The ISME journal 9 (3), 615-628, 2015 | 98 | 2015 |
| Structure and biosynthesis of the antibiotic bottromycin D Y Hou, MDB Tianero, JC Kwan, TP Wyche, CR Michel, GA Ellis, ... Organic letters 14 (19), 5050-5053, 2012 | 98 | 2012 |
| Isolation and Biological Evaluation of 8-epi-Malyngamide C from the Floridian Marine Cyanobacterium Lyngbya majuscula† JC Kwan, M Teplitski, SP Gunasekera, VJ Paul, H Luesch Journal of natural products 73 (3), 463-466, 2010 | 98 | 2010 |
| Accessing chemical diversity from the uncultivated symbionts of small marine animals TE Smith, CD Pond, E Pierce, ZP Harmer, J Kwan, MM Zachariah, ... Nature chemical biology 14 (2), 179-185, 2018 | 92 | 2018 |
| Lyngbyastatins 8–10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena JC Kwan, K Taori, VJ Paul, H Luesch Marine drugs 7 (4), 528-538, 2009 | 89 | 2009 |
| A bacterial source for mollusk pyrone polyketides Z Lin, JP Torres, MA Ammon, L Marett, RW Teichert, CA Reilly, JC Kwan, ... Chemistry & biology 20 (1), 73-81, 2013 | 88 | 2013 |
| Microbial-derived products as potential new antimicrobials BS Seal, D Drider, BB Oakley, H Brüssow, D Bikard, JO Rich, S Miller, ... Veterinary research 49 (1), 1-12, 2018 | 83 | 2018 |
| Autometa: automated extraction of microbial genomes from individual shotgun metagenomes IJ Miller, ER Rees, J Ross, I Miller, J Baxa, J Lopera, RL Kerby, FE Rey, ... Nucleic acids research 47 (10), e57-e57, 2019 | 80 | 2019 |
| Molassamide, a Depsipeptide Serine Protease Inhibitor from the Marine Cyanobacterium Dichothrix utahensis SP Gunasekera, MW Miller, JC Kwan, H Luesch, VJ Paul Journal of natural products 73 (3), 459-462, 2010 | 79 | 2010 |
| Total structure determination of grassypeptolide, a new marine cyanobacterial cytotoxin JC Kwan, JR Rocca, KA Abboud, VJ Paul, H Luesch Organic letters 10 (5), 789-792, 2008 | 79 | 2008 |
| Grassypeptolides A− C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides JC Kwan, R Ratnayake, KA Abboud, VJ Paul, H Luesch The Journal of organic chemistry 75 (23), 8012-8023, 2010 | 70 | 2010 |
| Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism JC Kwan, EW Schmidt PloS one 8 (12), e80822, 2013 | 59 | 2013 |
| Horizontal gene transfer to a defensive symbiont with a reduced genome in a multipartite beetle microbiome SC Waterworth, LV Flórez, ER Rees, C Hertweck, M Kaltenpoth, JC Kwan MBio 11 (1), e02430-19, 2020 | 55 | 2020 |
| Lack of overt genome reduction in the bryostatin-producing bryozoan symbiont “Candidatus Endobugula sertula” IJ Miller, N Vanee, SS Fong, GE Lim-Fong, JC Kwan Applied and environmental microbiology 82 (22), 6573-6583, 2016 | 47 | 2016 |
