Ikuti
Masahiro Morita
Masahiro Morita
Associate Professor with Tenure (principal investigator), Dept of Mol Med and Barshop Institute
Email yang diverifikasi di uthscsa.edu
Judul
Dikutip oleh
Dikutip oleh
Tahun
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
8742013
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
M Morita, SP Gravel, L Hulea, O Larsson, M Pollak, J St-Pierre, ...
Cell Cycle 14 (4), 473-480, 2015
5572015
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT
MR Fabian, MK Cieplak, F Frank, M Morita, J Green, T Srikumar, B Nagar, ...
Nature structural & molecular biology 18 (11), 1211-1217, 2011
4172011
mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
M Morita, J Prudent, K Basu, V Goyon, S Katsumura, L Hulea, D Pearl, ...
Molecular Cell 67 (6), 922-935. e5, 2017
3422017
La-related protein 1 (LARP1) represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1)
BD Fonseca, C Zakaria, JJ Jia, TE Graber, Y Svitkin, S Tahmasebi, ...
Journal of Biological Chemistry 290 (26), 15996-16020, 2015
2992015
nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
V Gandin, L Masvidal, L Hulea, SP Gravel, M Cargnello, S McLaughlan, ...
Genome research 26 (5), 636-648, 2016
2442016
Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale
V Gandin, K Sikström, T Alain, M Morita, S McLaughlan, O Larsson, ...
JoVE (Journal of Visualized Experiments), e51455, 2014
2432014
Distinct perturbation of the translatome by the antidiabetic drug metformin
O Larsson, M Morita, I Topisirovic, T Alain, MJ Blouin, M Pollak, ...
Proceedings of the National Academy of Sciences 109 (23), 8977-8982, 2012
2342012
A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development
M Morita, LW Ler, MR Fabian, N Siddiqui, M Mullin, VC Henderson, ...
Molecular and cellular biology 32 (17), 3585-3593, 2012
2292012
eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies
T Alain, M Morita, BD Fonseca, A Yanagiya, N Siddiqui, M Bhat, D Zammit, ...
Cancer research 72 (24), 6468-6476, 2012
1982012
Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1
C Rouya, N Siddiqui, M Morita, TF Duchaine, MR Fabian, N Sonenberg
Rna 20 (9), 1398-1409, 2014
1702014
The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability
K Ito, A Takahashi, M Morita, T Suzuki, T Yamamoto
Protein & cell 2 (9), 755-763, 2011
1622011
Multifunctional roles of the mammalian CCR4–NOT complex in physiological phenomena
YT Shirai, T Suzuki, M Morita, A Takahashi, T Yamamoto
Frontiers in genetics 5, 286, 2014
1572014
Translation is actively regulated during the differentiation of CD8 (+) effector T cells.
K Araki, M Morita, AG Bederman, BT Konieczny, HT Kissick, N Sonenberg, ...
Nature immunology 18 (9), 1046, 2017
1562017
Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth
M Morita, T Suzuki, T Nakamura, K Yokoyama, T Miyasaka, T Yamamoto
Molecular and cellular biology 27 (13), 4980-4990, 2007
1382007
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly
V Gandin, L Masvidal, M Cargnello, L Gyenis, S McLaughlan, Y Cai, ...
Nature communications 7 (1), 11127, 2016
1182016
Crystal structure of the human CNOT6L nuclease domain reveals strict poly (A) substrate specificity
H Wang, M Morita, X Yang, T Suzuki, W Yang, J Wang, K Ito, Q Wang, ...
The EMBO journal 29 (15), 2566-2576, 2010
1172010
Obesity resistance and increased hepatic expression of catabolism‐related mRNAs in Cnot3+/− mice
M Morita, Y Oike, T Nagashima, T Kadomatsu, M Tabata, T Suzuki, ...
The EMBO journal 30 (22), 4678-4691, 2011
992011
CNOT2 depletion disrupts and inhibits the CCR4–NOT deadenylase complex and induces apoptotic cell death
K Ito, T Inoue, K Yokoyama, M Morita, T Suzuki, T Yamamoto
Genes to Cells 16 (4), 368-379, 2011
852011
Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
L Hulea, SP Gravel, M Morita, M Cargnello, O Uchenunu, YK Im, ...
Cell metabolism 28 (6), 817-832. e8, 2018
822018
Sistem tidak dapat melakukan operasi ini. Coba lagi nanti.
Artikel 1–20