| Time-dependent changes in opsonin amount associated on nanoparticles alter their hepatic uptake characteristics S Nagayama, K Ogawara, Y Fukuoka, K Higaki, T Kimura International journal of pharmaceutics 342 (1-2), 215-221, 2007 | 284 | 2007 |
| Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use C Amnuaikit, I Ikeuchi, K Ogawara, K Higaki, T Kimura International journal of pharmaceutics 289 (1-2), 167-178, 2005 | 245 | 2005 |
| Pre-coating with serum albumin reduces receptor-mediated hepatic disposition of polystyrene nanosphere: implications for rational design of nanoparticles K Ogawara, K Furumoto, S Nagayama, K Minato, K Higaki, T Kai, ... Journal of controlled release 100 (3), 451-455, 2004 | 235 | 2004 |
| Prolongation of residence time of liposome by surface-modification with mixture of hydrophilic polymers T Shehata, K Ogawara, K Higaki, T Kimura International journal of pharmaceutics 359 (1-2), 272-279, 2008 | 178 | 2008 |
| A Novel Strategy to Modify Adenovirus Tropism and Enhance Transgene Delivery to Activated Vascular Endothelial Cells In Vitro and In Vivo K Ogawara, MG Rots, RJ Kok, HE Moorlag, AM Van Loenen, DKF Meijer, ... Human gene therapy 15 (5), 433-443, 2004 | 178 | 2004 |
| PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy Y Yoshizawa, Y Kono, K Ogawara, T Kimura, K Higaki International journal of pharmaceutics 412 (1-2), 132-141, 2011 | 172 | 2011 |
| Hepatic uptake of polystyrene microspheres in rats: effect of particle size on intrahepatic distribution K Ogawara, M Yoshida, K Higaki, T Kimura, K Shiraishi, M Nishikawa, ... Journal of Controlled Release 59 (1), 15-22, 1999 | 169 | 1999 |
| Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases JM Kuldo, KI Ogawara, N Werner, SA Ásgeirsdóttir, JAAM Kamps, RJ Kok, ... Current vascular pharmacology 3 (1), 11-39, 2005 | 122 | 2005 |
| In vivo anti-tumor effect of PEG liposomal doxorubicin (DOX) in DOX-resistant tumor-bearing mice: Involvement of cytotoxic effect on vascular endothelial cells K Ogawara, K Un, K Tanaka, K Higaki, T Kimura Journal of controlled release 133 (1), 4-10, 2009 | 118 | 2009 |
| Determinants for in vivo anti-tumor effects of PEG liposomal doxorubicin: importance of vascular permeability within tumors K Ogawara, K Un, K Minato, K Tanaka, K Higaki, T Kimura International journal of pharmaceutics 359 (1-2), 234-240, 2008 | 104 | 2008 |
| Effect of coupling of albumin onto surface of PEG liposome on its in vivo disposition K Furumoto, JI Yokoe, K Ogawara, S Amano, M Takaguchi, K Higaki, ... International journal of pharmaceutics 329 (1-2), 110-116, 2007 | 104 | 2007 |
| Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats J Yokoe, S Sakuragi, K Yamamoto, T Teragaki, K Ogawara, K Higaki, ... International journal of pharmaceutics 353 (1-2), 28-34, 2008 | 102 | 2008 |
| Appearance of double peaks in plasma concentration–time profile after oral administration depends on gastric emptying profile and weight function Y Metsugi, Y Miyaji, K Ogawara, K Higaki, T Kimura Pharmaceutical research 25, 886-895, 2008 | 80 | 2008 |
| Role of P‐glycoprotein as a secretory mechanism in quinidine absorption from rat small intestine Y Emi, D Tsunashima, KI Ogawara, K Higaki, T Kimura Journal of pharmaceutical sciences 87 (3), 295-299, 1998 | 73 | 1998 |
| Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor S Nagayama, K Ogawara, K Minato, Y Fukuoka, Y Takakura, M Hashida, ... International journal of pharmaceutics 329 (1-2), 192-198, 2007 | 71 | 2007 |
| Surface hydrophobicity of particles is not necessarily the most important determinant in their in vivo disposition after intravenous administration in rats K Ogawara, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura Journal of controlled release 77 (3), 191-198, 2001 | 69 | 2001 |
| Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor K Furumoto, S Nagayama, K Ogawara, Y Takakura, M Hashida, K Higaki, ... Journal of controlled release 97 (1), 133-141, 2004 | 68 | 2004 |
| Biliary excretion of polystyrene microspheres depends on the type of receptor-mediated uptake in rat liver K Furumoto, K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1526 (2), 221-226, 2001 | 59 | 2001 |
| Estimation of intradermal disposition kinetics of drugs: II. Factors determining penetration of drugs from viable skin to muscular layer K Higaki, M Asai, T Suyama, K Nakayama, K Ogawara, T Kimura International journal of pharmaceutics 239 (1-2), 129-141, 2002 | 58 | 2002 |
| Enhancement of topical delivery of drugs via direct penetration by reducing blood flow rate in skin K Higaki, K Nakayama, T Suyama, C Amnuaikit, K Ogawara, T Kimura International journal of pharmaceutics 288 (2), 227-233, 2005 | 55 | 2005 |
Grietje Molemaprofessor of Life Sciences University of GroningenEmail yang diverifikasi di umcg.nl