The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress M Lutter, I Sakata, S Osborne-Lawrence, SA Rovinsky, JG Anderson, ... Nature neuroscience 11 (7), 752-753, 2008 | 780 | 2008 |
Ghrelin-producing cells exist as two types of cells, closed-and opened-type cells, in the rat gastrointestinal tract I Sakata, K Nakamura, M Yamazaki, M Matsubara, Y Hayashi, K Kangawa, ... Peptides 23 (3), 531-536, 2002 | 480 | 2002 |
Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner M Perello, I Sakata, S Birnbaum, JC Chuang, S Osborne-Lawrence, ... Biological psychiatry 67 (9), 880-886, 2010 | 437 | 2010 |
Ghrelin mediates stress-induced food-reward behavior in mice JC Chuang, M Perello, I Sakata, S Osborne-Lawrence, JM Savitt, M Lutter, ... The Journal of clinical investigation 121 (7), 2684-2692, 2011 | 396 | 2011 |
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin KL Egerod, MS Engelstoft, KV Grunddal, MK Nøhr, A Secher, I Sakata, ... Endocrinology 153 (12), 5782-5795, 2012 | 357 | 2012 |
Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells MS Engelstoft, W Park, I Sakata, LV Kristensen, AS Husted, ... Molecular metabolism 2 (4), 376-392, 2013 | 354 | 2013 |
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice T Fujikawa, JC Chuang, I Sakata, G Ramadori, R Coppari Proceedings of the National Academy of Sciences 107 (40), 17391-17396, 2010 | 262 | 2010 |
Ghrelin secretion stimulated by β1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice TJ Zhao, I Sakata, RL Li, G Liang, JA Richardson, MS Brown, JL Goldstein, ... Proceedings of the National Academy of Sciences 107 (36), 15868-15873, 2010 | 228 | 2010 |
Ghrelin cells in the gastrointestinal tract I Sakata, T Sakai International journal of peptides 2010 (1), 945056, 2010 | 185 | 2010 |
Ghrelin directly stimulates glucagon secretion from pancreatic α-cells JC Chuang, I Sakata, D Kohno, M Perello, S Osborne-Lawrence, JJ Repa, ... Molecular Endocrinology 25 (9), 1600-1611, 2011 | 181 | 2011 |
Growth hormone secretagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion I Sakata, M Yamazaki, K Inoue, Y Hayashi, K Kangawa, T Sakai Neuroscience letters 342 (3), 183-186, 2003 | 162 | 2003 |
Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells I Sakata, J Yang, CE Lee, S Osborne-Lawrence, SA Rovinsky, ... American Journal of Physiology-Endocrinology and Metabolism 297 (1), E134-E141, 2009 | 159 | 2009 |
Genetic tracing of Nav1. 8‐expressing vagal afferents in the mouse L Gautron, I Sakata, S Udit, JM Zigman, JN Wood, JK Elmquist Journal of Comparative Neurology 519 (15), 3085-3101, 2011 | 122 | 2011 |
Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1 N Fujitsuka, A Asakawa, A Morinaga, MS Amitani, H Amitani, G Katsuura, ... Molecular psychiatry 21 (11), 1613-1623, 2016 | 121 | 2016 |
Estrogen modulates ghrelin expression in the female rat stomach M Matsubara, I Sakata, R Wada, M Yamazaki, K Inoue, T Sakai Peptides 25 (2), 289-297, 2004 | 118 | 2004 |
Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain M Perello, MM Scott, I Sakata, CE Lee, JC Chuang, S Osborne‐Lawrence, ... Journal of Comparative Neurology 520 (2), 281-294, 2012 | 117 | 2012 |
Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells I Sakata, WM Park, AK Walker, PK Piper, JC Chuang, ... American Journal of Physiology-Endocrinology and Metabolism 302 (10), E1300 …, 2012 | 111 | 2012 |
Characterization of a novel ghrelin cell reporter mouse I Sakata, Y Nakano, S Osborne-Lawrence, SA Rovinsky, CE Lee, ... Regulatory peptides 155 (1-3), 91-98, 2009 | 104 | 2009 |
G protein-coupled receptor 120 signaling regulates ghrelin secretion in vivo and in vitro Z Gong, M Yoshimura, S Aizawa, R Kurotani, JM Zigman, T Sakai, ... American Journal of Physiology-Endocrinology and Metabolism 306 (1), E28-E35, 2014 | 95 | 2014 |
Existence of ghrelin-immunopositive and-expressing cells in the proventriculus of the hatching and adult chicken R Wada, I Sakata, H Kaiya, K Nakamura, Y Hayashi, K Kangawa, T Sakai Regulatory Peptides 111 (1-3), 123-128, 2003 | 85 | 2003 |