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The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress
M Lutter, I Sakata, S Osborne-Lawrence, SA Rovinsky, JG Anderson, ...
Nature neuroscience 11 (7), 752-753, 2008
7802008
Ghrelin-producing cells exist as two types of cells, closed-and opened-type cells, in the rat gastrointestinal tract
I Sakata, K Nakamura, M Yamazaki, M Matsubara, Y Hayashi, K Kangawa, ...
Peptides 23 (3), 531-536, 2002
4802002
Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner
M Perello, I Sakata, S Birnbaum, JC Chuang, S Osborne-Lawrence, ...
Biological psychiatry 67 (9), 880-886, 2010
4372010
Ghrelin mediates stress-induced food-reward behavior in mice
JC Chuang, M Perello, I Sakata, S Osborne-Lawrence, JM Savitt, M Lutter, ...
The Journal of clinical investigation 121 (7), 2684-2692, 2011
3962011
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
KL Egerod, MS Engelstoft, KV Grunddal, MK Nøhr, A Secher, I Sakata, ...
Endocrinology 153 (12), 5782-5795, 2012
3572012
Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells
MS Engelstoft, W Park, I Sakata, LV Kristensen, AS Husted, ...
Molecular metabolism 2 (4), 376-392, 2013
3542013
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
T Fujikawa, JC Chuang, I Sakata, G Ramadori, R Coppari
Proceedings of the National Academy of Sciences 107 (40), 17391-17396, 2010
2622010
Ghrelin secretion stimulated by β1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice
TJ Zhao, I Sakata, RL Li, G Liang, JA Richardson, MS Brown, JL Goldstein, ...
Proceedings of the National Academy of Sciences 107 (36), 15868-15873, 2010
2282010
Ghrelin cells in the gastrointestinal tract
I Sakata, T Sakai
International journal of peptides 2010 (1), 945056, 2010
1852010
Ghrelin directly stimulates glucagon secretion from pancreatic α-cells
JC Chuang, I Sakata, D Kohno, M Perello, S Osborne-Lawrence, JJ Repa, ...
Molecular Endocrinology 25 (9), 1600-1611, 2011
1812011
Growth hormone secretagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion
I Sakata, M Yamazaki, K Inoue, Y Hayashi, K Kangawa, T Sakai
Neuroscience letters 342 (3), 183-186, 2003
1622003
Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells
I Sakata, J Yang, CE Lee, S Osborne-Lawrence, SA Rovinsky, ...
American Journal of Physiology-Endocrinology and Metabolism 297 (1), E134-E141, 2009
1592009
Genetic tracing of Nav1. 8‐expressing vagal afferents in the mouse
L Gautron, I Sakata, S Udit, JM Zigman, JN Wood, JK Elmquist
Journal of Comparative Neurology 519 (15), 3085-3101, 2011
1222011
Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1
N Fujitsuka, A Asakawa, A Morinaga, MS Amitani, H Amitani, G Katsuura, ...
Molecular psychiatry 21 (11), 1613-1623, 2016
1212016
Estrogen modulates ghrelin expression in the female rat stomach
M Matsubara, I Sakata, R Wada, M Yamazaki, K Inoue, T Sakai
Peptides 25 (2), 289-297, 2004
1182004
Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain
M Perello, MM Scott, I Sakata, CE Lee, JC Chuang, S Osborne‐Lawrence, ...
Journal of Comparative Neurology 520 (2), 281-294, 2012
1172012
Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells
I Sakata, WM Park, AK Walker, PK Piper, JC Chuang, ...
American Journal of Physiology-Endocrinology and Metabolism 302 (10), E1300 …, 2012
1112012
Characterization of a novel ghrelin cell reporter mouse
I Sakata, Y Nakano, S Osborne-Lawrence, SA Rovinsky, CE Lee, ...
Regulatory peptides 155 (1-3), 91-98, 2009
1042009
G protein-coupled receptor 120 signaling regulates ghrelin secretion in vivo and in vitro
Z Gong, M Yoshimura, S Aizawa, R Kurotani, JM Zigman, T Sakai, ...
American Journal of Physiology-Endocrinology and Metabolism 306 (1), E28-E35, 2014
952014
Existence of ghrelin-immunopositive and-expressing cells in the proventriculus of the hatching and adult chicken
R Wada, I Sakata, H Kaiya, K Nakamura, Y Hayashi, K Kangawa, T Sakai
Regulatory Peptides 111 (1-3), 123-128, 2003
852003
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