Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA YF He, BZ Li, Z Li, P Liu, Y Wang, Q Tang, J Ding, Y Jia, Z Chen, L Li, ... Science 333 (6047), 1303-1307, 2011 | 3231 | 2011 |
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming CX Song, KE Szulwach, Q Dai, Y Fu, SQ Mao, L Lin, C Street, Y Li, ... Cell 153 (3), 678-691, 2013 | 618 | 2013 |
CRISPR-based chromatin remodeling of the endogenous Oct4 or Sox2 locus enables reprogramming to pluripotency P Liu, M Chen, Y Liu, LS Qi, S Ding Cell stem cell 22 (2), 252-261. e4, 2018 | 198 | 2018 |
Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a B Li, J Zhou, P Liu, J Hu, H Jin, Y Shimono, M Takahashi, G Xu Biochemical journal 405 (2), 369-378, 2007 | 113 | 2007 |
A modified “cross-talk” between histone H2B Lys-120 ubiquitination and H3 Lys-79 methylation A Darwanto, MP Curtis, M Schrag, W Kirsch, P Liu, G Xu, JW Neidigh, ... Journal of Biological Chemistry 285 (28), 21868-21876, 2010 | 75 | 2010 |
Deficiency in a glutamine-specific methyltransferase for release factor causes mouse embryonic lethality P Liu, S Nie, B Li, ZQ Yang, ZM Xu, J Fei, C Lin, R Zeng, GL Xu Molecular and Cellular Biology 30 (17), 4245-4253, 2010 | 52 | 2010 |
The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation Nature Neuroscience, 2023 | 44 | 2023 |
Sox2 and Klf4 as the functional core in pluripotency induction without exogenous Oct4 Z An, P Liu, J Zheng, C Si, T Li, Y Chen, T Ma, MQ Zhang, Q Zhou, S Ding Cell reports 29 (7), 1986-2000. e8, 2019 | 42 | 2019 |
Differentiation of pluripotent stem cells for regenerative medicine K Li, Y Kong, M Zhang, F Xie, P Liu, S Xu Biochemical and Biophysical Research Communications 471 (1), 1-4, 2016 | 30 | 2016 |
The future of iPS cells in advancing regenerative medicine P Liu, KE Li, S Xu Genetics Research 98, e4, 2016 | 10 | 2016 |
Generation of induced pluripotent cells by CRISPR activation P Liu, S Ding US Patent 12,146,166, 2024 | | 2024 |
Generation of induced pluripotent stem cells with polycistronic sox2, klf4, and optionally c-myc P Liu, S Ding US Patent App. 17/769,865, 2022 | | 2022 |
A Platform for the Generation of High-Quality Clonally-Derived Induced Pluripotent Stem Cell Lines for the Mass Production of Off-The-Shelf Cellular Therapeutics R Abujarour, YS Lai, G Bonello, M Robinson, C Ruller, M Pribadi, ... MOLECULAR THERAPY 28 (4), 529-530, 2020 | | 2020 |