| Secretory mechanisms and intercellular transfer of microRNAs in living cells*♦ N Kosaka, H Iguchi, Y Yoshioka, F Takeshita, Y Matsuki, T Ochiya Journal of Biological Chemistry 285 (23), 17442-17452, 2010 | 2307 | 2010 |
| Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis N Kosaka, H Iguchi, T Ochiya Cancer science 101 (10), 2087-2092, 2010 | 1662 | 2010 |
| Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis N Kosaka, H Iguchi, K Hagiwara, Y Yoshioka, F Takeshita, T Ochiya Journal of Biological Chemistry 288 (15), 10849-10859, 2013 | 871 | 2013 |
| Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells M Ono, N Kosaka, N Tominaga, Y Yoshioka, F Takeshita, R Takahashi, ... Science signaling 7 (332), ra63-ra63, 2014 | 739 | 2014 |
| Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier N Tominaga, N Kosaka, M Ono, T Katsuda, Y Yoshioka, K Tamura, ... Nature communications 6 (1), 6716, 2015 | 735 | 2015 |
| microRNA as a new immune-regulatory agent in breast milk N Kosaka, H Izumi, K Sekine, T Ochiya Silence 1, 1-8, 2010 | 660 | 2010 |
| Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen Y Yoshioka, N Kosaka, Y Konishi, H Ohta, H Okamoto, H Sonoda, ... Nature communications 5 (1), 3591, 2014 | 604 | 2014 |
| Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes T Katsuda, R Tsuchiya, N Kosaka, Y Yoshioka, K Takagaki, K Oki, ... Scientific reports 3 (1), 1197, 2013 | 601 | 2013 |
| Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes F Takeshita, L Patrawala, M Osaki, R Takahashi, Y Yamamoto, N Kosaka, ... Molecular Therapy 18 (1), 181-187, 2010 | 522 | 2010 |
| Comparative marker analysis of extracellular vesicles in different human cancer types Y Yoshioka, Y Konishi, N Kosaka, T Katsuda, T Kato, T Ochiya Journal of extracellular vesicles 2 (1), 20424, 2013 | 468 | 2013 |
| The therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles T Katsuda, N Kosaka, F Takeshita, T Ochiya Proteomics 13 (10-11), 1637-1653, 2013 | 465 | 2013 |
| Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo Y Minakuchi, F Takeshita, N Kosaka, H Sasaki, Y Yamamoto, M Kouno, ... Nucleic acids research 32 (13), e109-e109, 2004 | 439 | 2004 |
| Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions H Izumi, N Kosaka, T Shimizu, K Sekine, T Ochiya, M Takase Journal of dairy science 95 (9), 4831-4841, 2012 | 422 | 2012 |
| Bovine milk exosomes contain microRNA and mRNA and are taken up by human macrophages H Izumi, M Tsuda, Y Sato, N Kosaka, T Ochiya, H Iwamoto, K Namba, ... Journal of dairy science 98 (5), 2920-2933, 2015 | 374 | 2015 |
| The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families Y Murakami, H Toyoda, M Tanaka, M Kuroda, Y Harada, F Matsuda, ... PloS one 6 (1), e16081, 2011 | 369 | 2011 |
| Versatile roles of extracellular vesicles in cancer N Kosaka, Y Yoshioka, Y Fujita, T Ochiya The Journal of clinical investigation 126 (4), 1163-1172, 2016 | 360 | 2016 |
| Competitive interactions of cancer cells and normal cells via secretory microRNAs N Kosaka, H Iguchi, Y Yoshioka, K Hagiwara, F Takeshita, T Ochiya Journal of Biological Chemistry 287 (2), 1397-1405, 2012 | 343 | 2012 |
| MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma Y Yamamoto, N Kosaka, M Tanaka, F Koizumi, Y Kanai, T Mizutani, ... Biomarkers 14 (7), 529-538, 2009 | 312 | 2009 |
| MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression M Osaki, F Takeshita, Y Sugimoto, N Kosaka, Y Yamamoto, Y Yoshioka, ... Molecular therapy 19 (6), 1123-1130, 2011 | 307 | 2011 |
| Extracellular vesicles as biomarkers and therapeutic targets for cancer F Urabe, N Kosaka, K Ito, T Kimura, S Egawa, T Ochiya American Journal of Physiology-Cell Physiology, 2019 | 303 | 2019 |