| The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ... Cell reports 27 (4), 1293-1306. e6, 2019 | 734 | 2019 |
| Single-nucleus RNA-Seq is not suitable for detection of microglial activation genes in humans N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ... Cell reports 32 (13), 2020 | 272 | 2020 |
| Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology A Sierksma, A Lu, R Mancuso, N Fattorelli, N Thrupp, E Salta, J Zoco, ... EMBO molecular medicine 12 (3), e10606, 2020 | 255 | 2020 |
| MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease S Balusu, K Horré, N Thrupp, K Craessaerts, A Snellinx, L Serneels, ... Science 381 (6663), 1176-1182, 2023 | 127 | 2023 |
| Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease H Walgrave, S Balusu, S Snoeck, EV Eynden, K Craessaerts, N Thrupp, ... Cell Stem Cell 28 (10), 1805-1821. e8, 2021 | 119 | 2021 |
| Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease S Calafate, G Özturan, N Thrupp, J Vanderlinden, L Santa-Marinha, ... Nature neuroscience 26 (6), 1021-1031, 2023 | 33 | 2023 |
| microRNA-132 regulates gene expression programs involved in microglial homeostasis H Walgrave, A Penning, G Tosoni, S Snoeck, K Davie, E Davis, L Wolfs, ... Iscience 26 (6), 2023 | 24 | 2023 |
| Long noncoding RNA MEG3 activates neuronal necroptosis in Alzheimer’s disease S Balusu, K Horré, N Thrupp, A Snellinx, L Serneels, I Chrysidou, ... BioRxiv, 2022.02. 18.480849, 2022 | 13 | 2022 |
| Single nucleus sequencing fails to detect microglial activation in human tissue N Thrupp, CS Frigerio, L Wolfs, NG Skene, S Poovathingal, Y Fourne, ... bioRxiv, 2020.04. 13.035386, 2020 | 11 | 2020 |
| Impaired adult hippocampal neurogenesis in Alzheimer’s disease is mediated by microRNA-132 deficiency and can be restored by microRNA-132 replacement E Salta, H Walgrave, S Balusu, E Vanden Eynden, S Snoeck, ... BioRxiv, 2020.03. 12.988709, 2020 | 4 | 2020 |
| NACC2, a molecular effector of miR-132 regulation at the interface between adult neurogenesis and Alzheimer’s disease A Penning, S Snoeck, O Garritsen, G Tosoni, A Hof, F de Boer, ... Scientific Reports 14 (1), 21163, 2024 | 2 | 2024 |
| Transcriptomics to study the cellular phase of Alzheimer's Disease N Thrupp | 1 | 2023 |
| Putting computational models of immunity to the test-an invited challenge to predict B. pertussis vaccination outcomes P Shinde, L Willemsen, M Anderson, M Aoki, S Basu, JG Burel, P Cheng, ... bioRxiv, 2024.09. 04.611290, 2024 | | 2024 |
| Unbiased profiling of miR‐132 targetome with implications in adult hippocampal neurogenesis and Alzheimer’s disease A Penning, G Tosoni, H Walgrave, O Garritsen, S Snoeck, K Craessaerts, ... Alzheimer's & Dementia 17, e052013, 2021 | | 2021 |
| Melanin Concentrating Hormone-and sleep-dependent synaptic downscaling is impaired in Alzheimer’s Disease S Calafate, G Özturan, N Thrupp, J Vanderlinden, WT Chen, M Fiers, A Lu, ... bioRxiv, 2021.05. 21.445007, 2021 | | 2021 |
| microRNA-132 regulates adult neural stem cells and their progeny to restore hippocampal neurogenesis and memory in Alzheimer’s disease H Walgrave, S Balusu, S Snoeck, EV Eynden, K Craessaerts, N Thrupp, ... Cell Stem Cell, 2021 | | 2021 |
