Antibody structure, instability, and formulation W Wang, S Singh, DL Zeng, K King, S Nema Journal of pharmaceutical sciences 96 (1), 1-26, 2007 | 1293 | 2007 |
Impact of product-related factors on immunogenicity of biotherapeutics SK Singh Journal of pharmaceutical sciences 100 (2), 354-387, 2011 | 380 | 2011 |
An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics SK Singh, N Afonina, M Awwad, K Bechtold-Peters, JT Blue, D Chou, ... Journal of pharmaceutical sciences 99 (8), 3302-3321, 2010 | 366 | 2010 |
Controlled release: A quantitative treatment L Fan, SK Singh Springer Science & Business Media, 2012 | 330 | 2012 |
Immunogenicity of protein aggregates—concerns and realities W Wang, SK Singh, N Li, MR Toler, KR King, S Nema International journal of pharmaceutics 431 (1-2), 1-11, 2012 | 302 | 2012 |
diffGrad: an optimization method for convolutional neural networks SR Dubey, S Chakraborty, SK Roy, S Mukherjee, SK Singh, ... IEEE transactions on neural networks and learning systems 31 (11), 4500-4511, 2019 | 262 | 2019 |
Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo … DL Bhatt, PG Steg, SR Mehta, LA Leiter, T Simon, K Fox, C Held, ... The Lancet 394 (10204), 1169-1180, 2019 | 222 | 2019 |
Potential aggregation prone regions in biotherapeutics: a survey of commercial monoclonal antibodies X Wang, TK Das, SK Singh, S Kumar MAbs 1 (3), 254-267, 2009 | 222 | 2009 |
Impact of freezing on pH of buffered solutions and consequences for monoclonal antibody aggregation P Kolhe, E Amend, S K. Singh Biotechnology progress 26 (3), 727-733, 2010 | 201 | 2010 |
Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development DS Tomar, S Kumar, SK Singh, S Goswami, L Li MAbs 8 (2), 216-228, 2016 | 193 | 2016 |
Distinct aggregation mechanisms of monoclonal antibody under thermal and freeze-thaw stresses revealed by hydrogen exchange A Zhang, SK Singh, MR Shirts, S Kumar, EJ Fernandez Pharmaceutical research 29, 236-250, 2012 | 181 | 2012 |
Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of … JG Barnard, S Singh, TW Randolph, JF Carpenter Journal of pharmaceutical sciences 100 (2), 492-503, 2011 | 170 | 2011 |
Ophthalmic formulation of a selective cyclooxygenase-2 inhibitory drug T Kararli, R Bandyopadhyay, S Singh, L Hawley US Patent App. 09/904,098, 2002 | 168 | 2002 |
Aggregation in protein-based biotherapeutics: computational studies and tools to identify aggregation-prone regions NJ Agrawal, S Kumar, X Wang, B Helk, SK Singh, BL Trout Journal of pharmaceutical sciences 100 (12), 5081-5095, 2011 | 157 | 2011 |
Frozen state storage instability of a monoclonal antibody: aggregation as a consequence of trehalose crystallization and protein unfolding SK Singh, P Kolhe, AP Mehta, SC Chico, AL Lary, M Huang Pharmaceutical research 28, 873-885, 2011 | 145 | 2011 |
Concentration dependent viscosity of monoclonal antibody solutions: explaining experimental behavior in terms of molecular properties L Li, S Kumar, PM Buck, C Burns, J Lavoie, SK Singh, NW Warne, ... Pharmaceutical research 31, 3161-3178, 2014 | 140 | 2014 |
Hydrodynamic and thermodynamic aspects of the SDS-EHEC-water system C Holmberg, S Nilsson, SK Singh, LO Sundeloef The Journal of Physical Chemistry 96 (2), 871-876, 1992 | 126 | 1992 |
Highly viscous antibody solutions are a consequence of network formation caused by domain–domain electrostatic complementarities: insights from coarse-grained simulations PM Buck, A Chaudhri, S Kumar, SK Singh Molecular pharmaceutics 12 (1), 127-139, 2015 | 121 | 2015 |
Considerations for the use of polysorbates in biopharmaceuticals MT Jones, HC Mahler, S Yadav, D Bindra, V Corvari, RM Fesinmeyer, ... Pharmaceutical Research 35, 1-8, 2018 | 111 | 2018 |
Large-scale freezing of biologics—a practitioner's review, part one: fundamental aspects SK Singh, P Kolhe, W Wang, S Nema BioProcess Int 7 (10), 32-44, 2009 | 110 | 2009 |