| The systems biology graphical notation NL Novère, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ... Nature biotechnology 27 (8), 735-741, 2009 | 1079 | 2009 |
| The BioPAX community standard for pathway data sharing E Demir, MP Cary, S Paley, K Fukuda, C Lemer, I Vastrik, G Wu, ... Nature biotechnology 28 (9), 935-942, 2010 | 817 | 2010 |
| Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I … T Furuta, H Takemura, ZY Liao, GJ Aune, C Redon, OA Sedelnikova, ... Journal of Biological Chemistry 278 (22), 20303-20312, 2003 | 578 | 2003 |
| ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage MI Aladjem, BT Spike, LW Rodewald, TJ Hope, M Klemm, R Jaenisch, ... Current Biology 8 (3), 145-155, 1998 | 544 | 1998 |
| Participation of the human β-globin locus control region in initiation of DNA replication MI Aladjem, M Groudine, LL Brody, ES Dieken, REK Fournier, GM Wahl, ... Science 270 (5237), 815-819, 1995 | 285 | 1995 |
| Genetic dissection of a mammalian replicator in the human β-globin locus MI Aladjem, LW Rodewald, JL Kolman, GM Wahl Science 281 (5379), 1005-1009, 1998 | 264 | 1998 |
| The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and-DNA fiber analyses JA Seiler, C Conti, A Syed, MI Aladjem, Y Pommier Molecular and cellular biology 27 (16), 5806-5818, 2007 | 254 | 2007 |
| SLFN11 blocks stressed replication forks independently of ATR J Murai, SW Tang, E Leo, SA Baechler, CE Redon, H Zhang, M Al Abo, ... Molecular cell 69 (3), 371-384. e6, 2018 | 247 | 2018 |
| Replication in context: dynamic regulation of DNA replication patterns in metazoans MI Aladjem Nature Reviews Genetics 8 (8), 588-600, 2007 | 241 | 2007 |
| Dual roles of poly (dA: dT) tracts in replication initiation and fork collapse A Tubbs, S Sridharan, N van Wietmarschen, Y Maman, E Callen, ... Cell 174 (5), 1127-1142. e19, 2018 | 202 | 2018 |
| Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes M Regairaz, YW Zhang, H Fu, KK Agama, N Tata, S Agrawal, MI Aladjem, ... Journal of Cell Biology 195 (5), 739-749, 2011 | 192 | 2011 |
| Molecular interaction maps of bioregulatory networks: a general rubric for systems biology KW Kohn, MI Aladjem, JN Weinstein, Y Pommier Molecular biology of the cell 17 (1), 1-13, 2006 | 172 | 2006 |
| Phase I study of ATR inhibitor M6620 in combination with topotecan in patients with advanced solid tumors A Thomas, CE Redon, L Sciuto, E Padiernos, J Ji, MJ Lee, A Yuno, S Lee, ... Journal of Clinical Oncology 36 (16), 1594-1602, 2018 | 170 | 2018 |
| Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damage C Conti, E Leo, GS Eichler, O Sordet, MM Martin, A Fan, MI Aladjem, ... Cancer research 70 (11), 4470-4480, 2010 | 165 | 2010 |
| CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics A Luna, F Elloumi, S Varma, Y Wang, VN Rajapakse, MI Aladjem, ... Nucleic acids research 49 (D1), D1083-D1093, 2021 | 162 | 2021 |
| Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress A Thomas, N Takahashi, VN Rajapakse, X Zhang, Y Sun, M Ceribelli, ... Cancer cell 39 (4), 566-579. e7, 2021 | 154 | 2021 |
| Genome-wide depletion of replication initiation events in highly transcribed regions MM Martin, M Ryan, RG Kim, AL Zakas, H Fu, CM Lin, WC Reinhold, ... Genome research 21 (11), 1822-1832, 2011 | 152 | 2011 |
| ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin K Lee, H Fu, MI Aladjem, K Myung Journal of Cell Biology 200 (1), 31-44, 2013 | 139 | 2013 |
| SCLC-CellMiner: a resource for small cell lung cancer cell line genomics and pharmacology based on genomic signatures C Tlemsani, L Pongor, F Elloumi, L Girard, KE Huffman, N Roper, ... Cell reports 33 (3), 2020 | 126 | 2020 |
| CellMinerCDB for integrative cross-database genomics and pharmacogenomics analyses of cancer cell lines VN Rajapakse, A Luna, M Yamade, L Loman, S Varma, M Sunshine, ... Iscience 10, 247-264, 2018 | 124 | 2018 |
Augustin LunaInvestigator | Computational Biology Branch, NLM & Developmental Therapeutics Branch, NCI, NIHEmail yang diverifikasi di mail.nih.gov
