| HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites PD Kwong, ML Doyle, DJ Casper, C Cicala, SA Leavitt, S Majeed, ... Nature 420 (6916), 678-682, 2002 | 1181 | 2002 |
| Direct measurement of protein binding energetics by isothermal titration calorimetry S Leavitt, E Freire Current opinion in structural biology 11 (5), 560-566, 2001 | 1013 | 2001 |
| Isothermal titration calorimetry E Freire, OL Mayorga, M Straume Analytical chemistry 62 (18), 950A-959A, 1990 | 839 | 1990 |
| Thermodynamics of structural stability and cooperative folding behavior in proteins KP Murphy, E Freire Advances in protein chemistry 43, 313-361, 1992 | 838 | 1992 |
| Do enthalpy and entropy distinguish first in class from best in class? E Freire Drug discovery today 13 (19-20), 869-874, 2008 | 573 | 2008 |
| The heat capacity of proteins J Gómez, VJ Hilser, D Xie, E Freire Proteins: Structure, Function, and Bioinformatics 22 (4), 404-412, 1995 | 551 | 1995 |
| Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo Q Xu, LM Ensign, NJ Boylan, A Schon, X Gong, JC Yang, NW Lamb, ... ACS nano 9 (9), 9217-9227, 2015 | 547 | 2015 |
| Adding calorimetric data to decision making in lead discovery: a hot tip JE Ladbury, G Klebe, E Freire Nature reviews Drug discovery 9 (1), 23-27, 2010 | 487 | 2010 |
| Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems E Freire, RL Biltonen Biopolymers: Original Research on Biomolecules 17 (2), 463-479, 1978 | 480 | 1978 |
| Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ... Nature structural & molecular biology 22 (7), 522-531, 2015 | 392 | 2015 |
| The magnitude of the backbone conformational entropy change in protein folding JA D'aquino, J Gómez, VJ Hilser, KH Lee, LM Amzel, E Freire Proteins: Structure, Function, and Bioinformatics 25 (2), 143-156, 1996 | 368 | 1996 |
| Isothermal titration calorimetry to determine association constants for high-affinity ligands A Velazquez-Campoy, E Freire Nature protocols 1 (1), 186-191, 2006 | 363 | 2006 |
| Isothermal titration calorimetry A Velázquez‐Campoy, H Ohtaka, A Nezami, S Muzammil, E Freire Current protocols in cell biology 23 (1), 17.8. 1-17.8. 24, 2004 | 349 | 2004 |
| Forces and factors that contribute to the structural stability of membrane proteins T Haltia, E Freire Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1241 (2), 295-322, 1995 | 343 | 1995 |
| Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors VJ Hilser, E Freire Journal of molecular biology 262 (5), 756-772, 1996 | 337 | 1996 |
| Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins Z Si, N Madani, JM Cox, JJ Chruma, JC Klein, A Schön, N Phan, L Wang, ... Proceedings of the National Academy of Sciences 101 (14), 5036-5041, 2004 | 329 | 2004 |
| Differential scanning calorimetry E Freire Protein stability and folding: Theory and practice, 191-218, 1995 | 316 | 1995 |
| Calorimetrically determined dynamics of complex unfolding transitions in proteins E Freire, WW Osdol, OL Mayorga, JM Sanchez-Ruiz Annual review of biophysics and biophysical chemistry 19 (1), 159-188, 1990 | 311 | 1990 |
| Thermodynamic mapping of the inhibitor site of the aspartic protease endothiapepsin J Gómez, E Freire Journal of molecular biology 252 (3), 337-350, 1995 | 302 | 1995 |
| A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite NK Kisalu, AH Idris, C Weidle, Y Flores-Garcia, BJ Flynn, BK Sack, ... Nature medicine 24 (4), 408-416, 2018 | 283 | 2018 |
Adrian Velazquez-CampoyInstitute BIFI – University of ZaragozaEmail yang diverifikasi di unizar.es
