| Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model PE Sanchez, L Zhu, L Verret, KA Vossel, AG Orr, JR Cirrito, N Devidze, ... Proceedings of the National Academy of Sciences 109 (42), E2895-E2903, 2012 | 715 | 2012 |
| Reversing EphB2 depletion rescues cognitive functions in Alzheimer model M Cissé, B Halabisky, J Harris, N Devidze, DB Dubal, B Sun, A Orr, G Lotz, ... Nature 469 (7328), 47-52, 2011 | 521 | 2011 |
| Adenosine A2A receptor mediates microglial process retraction AG Orr, AL Orr, XJ Li, RE Gross, SF Traynelis Nature neuroscience 12 (7), 872-878, 2009 | 402 | 2009 |
| Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory AG Orr, EC Hsiao, MM Wang, K Ho, DH Kim, X Wang, W Guo, J Kang, ... Nature neuroscience 18 (3), 423-434, 2015 | 294 | 2015 |
| A subunit-selective potentiator of NR2C-and NR2D-containing NMDA receptors P Mullasseril, KB Hansen, KM Vance, KK Ogden, H Yuan, NL Kurtkaya, ... Nature communications 1 (1), 90, 2010 | 184 | 2010 |
| Activation of protease-activated receptor-1 triggers astrogliosis after brain injury O Nicole, A Goldshmidt, CE Hamill, SD Sorensen, A Sastre, ... Journal of Neuroscience 25 (17), 4319-4329, 2005 | 158 | 2005 |
| Istradefylline reduces memory deficits in aging mice with amyloid pathology AG Orr, I Lo, H Schumacher, K Ho, M Gill, W Guo, DH Kim, A Knox, T Saito, ... Neurobiology of disease 110, 29-36, 2018 | 87 | 2018 |
| Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... Molecular Neurodegeneration 17 (1), 41, 2022 | 79 | 2022 |
| Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1 G Mannaioni, AG Orr, CE Hamill, H Yuan, KH Pedone, KL McCoy, ... Journal of Biological Chemistry 283 (29), 20600-20611, 2008 | 78 | 2008 |
| Differential regulation of microglial motility by ATP/ADP and adenosine S Gyoneva, AG Orr, SF Traynelis Parkinsonism & related disorders 15, S195-S199, 2009 | 76 | 2009 |
| Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo A Acosta-Ruiz, VA Gutzeit, MJ Skelly, S Meadows, J Lee, P Parekh, ... Neuron 105 (3), 446-463. e13, 2020 | 73 | 2020 |
| Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate … KB Hansen, P Mullasseril, S Dawit, NL Kurtkaya, H Yuan, KM Vance, ... The Journal of pharmacology and experimental therapeutics 333 (3), 650-662, 2010 | 55 | 2010 |
| Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery CE Hamill, A Goldshmidt, O Nicole, RJ McKeon, DJ Brat, SF Traynelis Neurosurgery 52, 29-44, 2005 | 41 | 2005 |
| Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines A Licht-Murava, SM Meadows, F Palaguachi, SC Song, S Jackvony, ... Science Advances 9 (16), eade1282, 2023 | 28 | 2023 |
| Astrocytes in selective vulnerability to neurodegenerative disease TS Zimmer, AL Orr, AG Orr Trends in neurosciences, 2024 | 17 | 2024 |
| Astrocytes as drivers and disruptors of behavior: new advances in basic mechanisms and therapeutic targeting D Barnett, K Bohmbach, V Grelot, A Charlet, G Dallérac, YH Ju, J Nagai, ... Journal of Neuroscience 43 (45), 7463-7471, 2023 | 8 | 2023 |
| Hippocampal astrocytes induce sex-dimorphic effects on memory SM Meadows, F Palaguachi, MW Jang, A Licht-Murava, D Barnett, ... Cell reports 43 (6), 2024 | 6 | 2024 |
| Interleukin-1 mediates long-term hippocampal dentate granule cell loss following postnatal viral infection AG Orr, A Sharma, NB Binder, AH Miller, BD Pearce Journal of molecular neuroscience 41, 89-96, 2010 | 6 | 2010 |
| Astrocytes regulate spatial memory in a sex-specific manner SM Meadows, F Palaguachi, A Licht-Murava, D Barnett, TS Zimmer, ... BioRxiv, 2022.11. 03.511881, 2022 | 3 | 2022 |
| Effects of adenosine A2A receptors on cognitive function in health and disease CP Garcia, A Licht-Murava, AG Orr International Review of Neurobiology 170, 121-154, 2023 | 2 | 2023 |