Ikuti
Joschka Bauer
Joschka Bauer
Senior Scientist in Early Stage Pharmaceutical Development Biologicals at Boehringer Ingelheim
Email yang diverifikasi di boehringer-ingelheim.com
Judul
Dikutip oleh
Dikutip oleh
Tahun
Acidic residues control the dimerization of the N-terminal domain of black widow spiders’ major ampullate spidroin 1
J Bauer, D Schaal, L Eisoldt, K Schweimer, S Schwarzinger, T Scheibel
Scientific reports 6 (1), 34442, 2016
392016
Conformational stability and interplay of helical N-and C-terminal domains with implications on major ampullate spidroin assembly
J Bauer, T Scheibel
Biomacromolecules 18 (3), 835-845, 2017
342017
Dimerization of the conserved N-terminal domain of a spider silk protein controls the self-assembly of the repetitive core domain
J Bauer, T Scheibel
Biomacromolecules 18 (8), 2521-2528, 2017
272017
Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
J Bauer, S Mathias, S Kube, K Otte, P Garidel, M Gamer, M Blech, ...
MAbs 12 (1), 1787121, 2020
212020
Universal nanothin silk coatings via controlled spidroin self-assembly
RH Zha, P Delparastan, TD Fink, J Bauer, T Scheibel, PB Messersmith
Biomaterials science 7 (2), 683-695, 2019
212019
How can we discover developable antibody-based biotherapeutics?
J Bauer, N Rajagopal, P Gupta, P Gupta, AE Nixon, S Kumar
Frontiers in Molecular Biosciences 10, 1221626, 2023
192023
Modeling the impact of amino acid substitution in a monoclonal antibody on cation exchange chromatography
D Saleh, R Hess, M Ahlers‐Hesse, N Beckert, M Schönberger, ...
Biotechnology and Bioengineering 118 (8), 2923-2933, 2021
192021
Adaption of human antibody λ and κ light chain architectures to CDR repertoires
R van der Kant, J Bauer, AR Karow-Zwick, S Kube, P Garidel, M Blech, ...
Protein Engineering, Design and Selection 32 (3), 109-127, 2019
172019
Stress-dependent flexibility of a full-length human monoclonal antibody: Insights from molecular dynamics to support biopharmaceutical development
DS Tomar, G Licari, J Bauer, SK Singh, L Li, S Kumar
Journal of Pharmaceutical Sciences 111 (3), 628-637, 2022
122022
Embedding dynamics in intrinsic physicochemical profiles of market-stage antibody-based biotherapeutics
G Licari, KP Martin, M Crames, J Mozdzierz, MS Marlow, AR Karow-Zwick, ...
Molecular Pharmaceutics 20 (2), 1096-1111, 2022
112022
Resonance assignment of an engineered amino-terminal domain of a major ampullate spider silk with neutralized charge cluster
D Schaal, J Bauer, K Schweimer, T Scheibel, P Rösch, S Schwarzinger
Biomolecular NMR assignments 10, 199-202, 2016
22016
Predicting deamidation and isomerization sites in therapeutic antibodies using structure-based in silico approaches
D Hoffmann, J Bauer, M Kossner, A Henry, AR Karow-Zwick, G Licari
MAbs 16 (1), 2333436, 2024
12024
Biopharmaceutical Informatics: A Strategic Vision for Discovering Developable Biotherapeutic Drug Candidates
J Bauer, S Kube, P Gupta, S Kumar
Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical …, 2024
2024
Interfacial Protein Self-Assembly: An
TD Fink, P Delparastan, J Bauer, T Scheibel, P Messersmith, R Zha
2020 Virtual AIChE Annual Meeting, 2020
2020
Silk Protein Self-Assembly As a Pathway Towards Universal Nano-Thin Coatings
R Zha, TD Fink, P Delparastan, J Bauer, A Winkler, T Scheibel, ...
2018 AIChE Annual Meeting, 2018
2018
Wechselwirkungen zwischen Assemblierungsdomänen von Spinnenseidenproteinen
J Bauer
Universität Bayreuth, Bayreuther Graduiertenschule für Mathematik und …, 2018
2018
Die Schwarze Witwe und ihre Künste
J Bauer, T Scheibel
Spektrum 12 (2), 60-63, 2016
2016
Foundation of the outstanding toughness of biomimetic spider silk
T Scheibel, A Heidebrecht, C Thamm, J Bauer, F Kremer
Sheffield Silk Conference, 0
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