Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13555* | 2021 |
The integrated stress response K Pakos‐Zebrucka, I Koryga, K Mnich, M Ljujic, A Samali, AM Gorman EMBO reports 17 (10), 1374-1395, 2016 | 2314 | 2016 |
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, ... Nature communications 9 (1), 3267, 2018 | 257 | 2018 |
Regulation of lipid metabolism by the unfolded protein response M Moncan, K Mnich, A Blomme, A Almanza, A Samali, AM Gorman Journal of cellular and molecular medicine 25 (3), 1359-1370, 2021 | 126 | 2021 |
Controlling the unfolded protein response-mediated life and death decisions in cancer M Maurel, EP McGrath, K Mnich, S Healy, E Chevet, A Samali Seminars in cancer biology 33, 57-66, 2015 | 111 | 2015 |
Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival S Saveljeva, P Cleary, K Mnich, A Ayo, K Pakos-Zebrucka, JB Patterson, ... Oncotarget 7 (11), 12254, 2016 | 83 | 2016 |
The unfolded protein response in breast cancer EP McGrath, SE Logue, K Mnich, S Deegan, R Jäger, AM Gorman, ... Cancers 10 (10), 344, 2018 | 82 | 2018 |
Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat S Walsh, K Mnich, K Mackie, AM Gorman, DP Finn, E Dowd Brain research bulletin 81 (6), 543-548, 2010 | 61 | 2010 |
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner K Mnich, LA Carleton, ET Kavanagh, KM Doyle, A Samali, AM Gorman | 56 | 2014 |
Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β A Talty, S Deegan, M Ljujic, K Mnich, SD Naicker, D Quandt, Q Zeng, ... Cell death & disease 10 (9), 622, 2019 | 47 | 2019 |
HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis D Kennedy, K Mnich, D Oommen, R Chakravarthy, L Almeida-Souza, ... Cell Death & Disease 8 (8), e3026-e3026, 2017 | 45 | 2017 |
Inhibition by Anandamide of 6‐Hydroxydopamine‐Induced Cell Death in PC12 Cells K Mnich, DP Finn, E Dowd, AM Gorman International journal of cell biology 2010 (1), 818497, 2010 | 45 | 2010 |
Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer A Almanza, K Mnich, A Blomme, CM Robinson, G Rodriguez-Blanco, ... Nature communications 13 (1), 2493, 2022 | 44 | 2022 |
Nerve growth factor (NGF)-mediated regulation of p75NTR expression contributes to chemotherapeutic resistance in triple negative breast cancer cells R Chakravarthy, K Mnich, AM Gorman Biochemical and biophysical research communications 478 (4), 1541-1547, 2016 | 38 | 2016 |
An emerging role for the unfolded protein response in pancreatic cancer CM Robinson, A Talty, SE Logue, K Mnich, AM Gorman, A Samali Cancers 13 (2), 261, 2021 | 37 | 2021 |
RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells R Jaafar, K Mnich, S Dolan, J Hillis, A Almanza, SE Logue, A Samali, ... Biochemical and biophysical research communications 497 (1), 115-121, 2018 | 35 | 2018 |
Heat shock preconditioning protects against ER stress-induced apoptosis through the regulation of the BH3-only protein BIM D Kennedy, K Mnich, A Samali FEBS Open Bio 4, 813-821, 2014 | 33 | 2014 |
Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity LA Carleton, R Chakravarthy, AM van der Sloot, K Mnich, L Serrano, ... Biochemical and biophysical research communications 495 (1), 700-705, 2018 | 14 | 2018 |
The stressosome, a caspase‐8‐activating signalling complex assembled in response to cell stress in an ATG5‐mediated manner K Mnich, I Koryga, K Pakos‐Zebrucka, M Thomas, SE Logue, LA Eriksson, ... Journal of Cellular and Molecular Medicine 25 (18), 8809-8820, 2021 | 11 | 2021 |
Novel Pt (IV) prodrugs displaying antimitochondrial effects L Tabrizi, K Thompson, K Mnich, C Chintha, AM Gorman, L Morrison, ... Molecular Pharmaceutics 17 (8), 3009-3023, 2020 | 9 | 2020 |