Specific chemotherapy of Chagas disease: controversies and advances JA Urbina, R Docampo Trends in parasitology 19 (11), 495-501, 2003 | 779 | 2003 |
Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches JA Urbina Acta tropica 115 (1-2), 55-68, 2010 | 564 | 2010 |
Chemotherapy of trypanosomiases and leishmaniasis SL Croft, MP Barrett, JA Urbina Trends in parasitology 21 (11), 508-512, 2005 | 544 | 2005 |
Biomembrane phase transitions: studies of lipid-water systems using differential scanning calorimetry D Chapman, J Urbina, KM Keough Journal of Biological Chemistry 249 (8), 2512-2521, 1974 | 458 | 1974 |
Bisphosphonates Inhibit the Growth of Trypanosoma b rucei, Trypanosoma c ruzi, Leishmania d onovani, Toxoplasma g ondii, and Plasmodium f alciparum: A Potential Route to … MB Martin, JS Grimley, JC Lewis, HT Heath, BN Bailey, H Kendrick, ... Journal of medicinal chemistry 44 (6), 909-916, 2001 | 437 | 2001 |
Molecular order and dynamics of phosphatidylcholine bilayer membranes in the presence of cholesterol, ergosterol and lanosterol: a comparative study using 2H-, 13C-and 31P-NMR … JA Urbina, S Pekerar, H Le, J Patterson, B Montez, E Oldfield Biochimica et Biophysica Acta (BBA)-Biomembranes 1238 (2), 163-176, 1995 | 299 | 1995 |
The challenges of Chagas disease—grim outlook or glimmer of hope? RL Tarleton, R Reithinger, JA Urbina, U Kitron, RE Gürtler PLoS medicine 4 (12), e332, 2007 | 285 | 2007 |
Chemotherapy of Chagas disease JA Urbina Current pharmaceutical design 8 (4), 287-295, 2002 | 282 | 2002 |
Ergosterol biosynthesis and drug development for Chagas disease JA Urbina Memorias do Instituto Oswaldo Cruz 104, 311-318, 2009 | 281 | 2009 |
Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites JA Urbina Parasitology 114 (7), 91-99, 1997 | 263 | 1997 |
Amiodarone Has Intrinsic Anti-Trypanosoma cruzi Activity and Acts Synergistically with Posaconazole G Benaim, JM Sanders, Y Garcia-Marchán, C Colina, R Lira, AR Caldera, ... Journal of medicinal chemistry 49 (3), 892-899, 2006 | 252 | 2006 |
Toward a Novel Metal-Based Chemotherapy against Tropical Diseases. 2. Synthesis and Antimalarial Activity in Vitro and in Vivo of New Ruthenium− and … RA Sánchez-Delgado, M Navarro, H Pérez, JA Urbina Journal of Medicinal Chemistry 39 (5), 1095-1099, 1996 | 244 | 1996 |
Activities of the Triazole Derivative SCH 56592 (Posaconazole) against Drug-Resistant Strains of the Protozoan ParasiteTrypanosoma (Schizotrypanum) cruzi in … J Molina, O Martins-Filho, Z Brener, AJ Romanha, D Loebenberg, ... Antimicrobial agents and chemotherapy 44 (1), 150-155, 2000 | 236 | 2000 |
Cure of short-and long-term experimental Chagas' disease using D0870 JA Urbina, G Payares, J Molina, C Sanoja, A Liendo, K Lazardi, MM Piras, ... Science 273 (5277), 969-971, 1996 | 234 | 1996 |
Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region ME Grillet, JV Hernández-Villena, MS Llewellyn, AE Paniz-Mondolfi, ... The Lancet Infectious Diseases 19 (5), e149-e161, 2019 | 229 | 2019 |
Recent clinical trials for the etiological treatment of chronic Chagas disease: advances, challenges and perspectives JA Urbina Journal of Eukaryotic Microbiology 62 (1), 149-156, 2015 | 222 | 2015 |
Antiproliferative Effects and Mechanism of Action of SCH 56592 against Trypanosoma (Schizotrypanum)cruzi: In Vitro and In Vivo Studies JA Urbina, G Payares, LM Contreras, A Liendo, C Sanoja, J Molina, ... Antimicrobial Agents and Chemotherapy 42 (7), 1771-1777, 1998 | 217 | 1998 |
Nitrogen-containing bisphosphonates as carbocation transition state analogs for isoprenoid biosynthesis MB Martin, W Arnold, HT Heath III, JA Urbina, E Oldfield Biochemical and biophysical research communications 263 (3), 754-758, 1999 | 210 | 1999 |
In vitro and in vivo activities of ravuconazole on Trypanosoma cruzi, the causative agent of Chagas disease JA Urbina, G Payares, C Sanoja, R Lira, AJ Romanha International journal of antimicrobial agents 21 (1), 27-38, 2003 | 205 | 2003 |
Trypanosoma cruzi contains major pyrophosphate stores, and its growth in vitro and in vivo is blocked by pyrophosphate analogs JA Urbina, B Moreno, S Vierkotter, E Oldfield, G Payares, C Sanoja, ... Journal of Biological Chemistry 274 (47), 33609-33615, 1999 | 195 | 1999 |