| Association of mutations contributing to clonal hematopoiesis with prognosis in chronic ischemic heart failure L Dorsheimer, B Assmus, T Rasper, CA Ortmann, A Ecke, ... JAMA cardiology 4 (1), 25-33, 2019 | 432 | 2019 |
| Pooled in vitro and in vivo CRISPR-Cas9 screening identifies tumor suppressors in human colon organoids BE Michels, MH Mosa, BI Streibl, T Zhan, C Menche, K Abou-El-Ardat, ... Cell Stem Cell 26 (5), 782-792. e7, 2020 | 189 | 2020 |
| Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas K Abou-El-Ardat, M Seifert, K Becker, S Eisenreich, M Lehmann, ... Neuro-oncology 19 (4), 546-557, 2017 | 123 | 2017 |
| Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A- and TET2-driver gene mutations B Assmus, S Cremer, K Kirschbaum, D Culmann, K Kiefer, L Dorsheimer, ... European heart journal 42 (3), 257-265, 2021 | 116 | 2021 |
| Gravity‐sensitive signaling drives 3‐dimensional formation of multicellular thyroid cancer spheroids J Grosse, M Wehland, J Pietsch, H Schulz, K Saar, N Hübner, C Elles, ... The FASEB Journal 26 (12), 5124-5140, 2012 | 104 | 2012 |
| LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU. 1 target genes and induces differentiation in AML J Barth, K Abou-El-Ardat, D Dalic, N Kurrle, AM Maier, S Mohr, J Schütte, ... Leukemia 33 (6), 1411-1426, 2019 | 70 | 2019 |
| Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells S Zielke, N Meyer, M Mari, K Abou-El-Ardat, F Reggiori, SJL van Wijk, ... Cell death & disease 9 (10), 994, 2018 | 65 | 2018 |
| Functional dominance of CHIP-mutated hematopoietic stem cells in patients undergoing autologous transplantation CA Ortmann, L Dorsheimer, K Abou-El-Ardat, J Hoffrichter, B Assmus, ... Cell reports 27 (7), 2022-2028. e3, 2019 | 61 | 2019 |
| Epigallocatechin-3-gallate induces apoptosis and cell cycle arrest in HTLV-1-positive and-negative leukemia cells S Harakeh, K Abu-El-Ardat, M Diab-Assaf, A Niedzwiecki, M El-Sabban, ... Medical Oncology 25, 30-39, 2008 | 54 | 2008 |
| Multiple somatic mutations for clonal hematopoiesis are associated with increased mortality in patients with chronic heart failure S Cremer, K Kirschbaum, A Berkowitsch, D John, K Kiefer, L Dorsheimer, ... Circulation: Genomic and Precision Medicine 13 (4), e003003, 2020 | 52 | 2020 |
| Chronic exposure to simulated space conditions predominantly affects cytoskeleton remodeling and oxidative stress response in mouse fetal fibroblasts M Beck, M Moreels, R Quintens, K Abou-El-Ardat, H El-Saghire, K Tabury, ... International Journal of Molecular Medicine 34 (2), 606-615, 2014 | 46 | 2014 |
| Ascorbic acid induces apoptosis in adult T-cell leukemia S Harakeh, M Diab-Assaf, JC Khalife, KA Abu-El-Ardat, E Baydoun, ... Anticancer research 27 (1A), 289-298, 2007 | 45 | 2007 |
| Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53 P Malkomes, I Lunger, E Oppermann, K Abou-El-Ardat, T Oellerich, ... Oncogene 40 (25), 4352-4367, 2021 | 36 | 2021 |
| Mutant IDH1 differently affects redox state and metabolism in glial cells of normal and tumor origin J Biedermann, M Preussler, M Conde, M Peitzsch, S Richter, ... Cancers 11 (12), 2028, 2019 | 34 | 2019 |
| Full spectrum of clonal haematopoiesis‐driver mutations in chronic heart failure and their associations with mortality KC Kiefer, S Cremer, E Pardali, B Assmus, K Abou‐El‐Ardat, ... ESC heart failure 8 (3), 1873-1884, 2021 | 33 | 2021 |
| Autoregressive higher-order hidden Markov models: exploiting local chromosomal dependencies in the analysis of tumor expression profiles M Seifert, K Abou-El-Ardat, B Friedrich, B Klink, A Deutsch PloS one 9 (6), e100295, 2014 | 30 | 2014 |
| Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells K Abou-El-Ardat, P Monsieurs, N Anastasov, M Atkinson, H Derradji, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 731 (1 …, 2012 | 30 | 2012 |
| Iodine-deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a vascular endothelial growth factor–hypoxia inducible factor-1–dependent, but not a … AC Gérard, K Humblet, C Wilvers, S Poncin, H Derradji, ... Thyroid 22 (7), 699-708, 2012 | 28 | 2012 |
| Epigallocatechin-3-gallate inhibits tax-dependent activation of nuclear factor kappa B and of matrix metalloproteinase 9 in human T-cell lymphotropic virus-1 positive leukemia … SM Harakeh, M Diab-Assaf, R Azar, HMA Hassan, S Tayeb, ... Asian Pacific Organization for Cancer Prevention, 2014 | 27 | 2014 |
| Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects H Derradji, S Bekaert, T De Meyer, P Jacquet, K Abou-El-Ardat, M Ghardi, ... Developmental Biology 322 (2), 302-313, 2008 | 27 | 2008 |
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