Stefan Knapp

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	Semua	Sejak 2020
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409 artikel

60 artikel

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Panagis FilippakopoulosAssociate Professor, Oxford UniversityEmail yang diverifikasi di sgc.ox.ac.uk
Oleg FedorovUniversity of OxfordEmail yang diverifikasi di cmd.ox.ac.uk
Apirat ChaikuadEmail yang diverifikasi di pharmchem.uni-frankfurt.de
Paul E BrennanUniversity of OxfordEmail yang diverifikasi di cmd.ox.ac.uk
Frank von DelftPrincipal Investigator: Protein Crystallography, SGC, Oxford UniversityEmail yang diverifikasi di sgc.ox.ac.uk
Brian MarsdenCentre for Medicines Discovery & Centre for Human Genetics, NDM, University of OxfordEmail yang diverifikasi di cmd.ox.ac.uk
Cheryl ArrowsmithSenior Scientist, Princess Margaret Cancer Centre & Professor of Medical Biophysics, University of TorontoEmail yang diverifikasi di uhnres.utoronto.ca
Sebastian MatheaEmail yang diverifikasi di pharmchem.uni-frankfurt.de
Wen Hwa LeeAction Against AMD, SGC and University of OxfordEmail yang diverifikasi di actionagainstamd.org
Benjamin E. TurkYale UniversityEmail yang diverifikasi di yale.edu
Jeyanthy EswaranSaint Jude's Children's Research HospitalEmail yang diverifikasi di stjude.org
Chas BountraProfessor of Translational MedicineEmail yang diverifikasi di cmd.ox.ac.uk
Martin SchröderNovartis Institute for Biomedical ResearchEmail yang diverifikasi di novartis.com
Opher GileadiSGC, Karolinska InstituteEmail yang diverifikasi di ki.se
Ashley PikeCentre for Medicines Discovery - University of OxfordEmail yang diverifikasi di cmd.ox.ac.uk
Juerg SchwallerProfessor Universität BaselEmail yang diverifikasi di unibas.ch
Kilian V. M. HuberPrincipal Investigator, University of OxfordEmail yang diverifikasi di cmd.ox.ac.uk
Stuart J ConwayJung Chair in Medicinal Chemistry, University of California, Los AngelesEmail yang diverifikasi di chem.ucla.edu
Daniel MerkETH Zurich, Switzerland; Goethe University Frankfurt, GermanyEmail yang diverifikasi di pharmchem.uni-frankfurt.de
Laurent MeijerEmail yang diverifikasi di manros-therapeutics.com

Ikuti

Stefan Knapp

University of Frankfurt

Email yang diverifikasi di pharmchem.uni-frankfurt.de

bromodomains kinases structural biology drug design


Judul Urutkan menurut kutipan Urutkan menurut tahun Urutkan menurut judul	Dikutip oleh Dikutip oleh	Tahun
Selective inhibition of BET bromodomains P Filippakopoulos, J Qi, S Picaud, Y Shen, WB Smith, O Fedorov, ... Nature 468 (7327), 1067-1073, 2010	4529	2010
Histone recognition and large-scale structural analysis of the human bromodomain family P Filippakopoulos, S Picaud, M Mangos, T Keates, JP Lambert, ... Cell 149 (1), 214-231, 2012	1840	2012
Targeting bromodomains: epigenetic readers of lysine acetylation P Filippakopoulos, S Knapp Nature reviews Drug discovery 13 (5), 337-356, 2014	1379	2014
Protein production and purification Architecture et Fonction des Macromolécules Biologiques Vincentelli Renaud 4 ... Nature methods 5 (2), 135-146, 2008	1035	2008
The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature chemical biology 11 (8), 536-541, 2015	895	2015
Critical residues for structure and catalysis in short-chain dehydrogenases/reductases C Filling, KD Berndt, J Benach, S Knapp, T Prozorovski, E Nordling, ... Journal of Biological Chemistry 277 (28), 25677-25684, 2002	705	2002
The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs KL Kavanagh, K Guo, JE Dunford, X Wu, S Knapp, FH Ebetino, ... Proceedings of the National Academy of Sciences 103 (20), 7829-7834, 2006	678	2006
Trends in kinase drug discovery: targets, indications and inhibitor design MM Attwood, D Fabbro, AV Sokolov, S Knapp, HB Schiöth Nature Reviews Drug Discovery 20 (11), 839-861, 2021	609	2021
Copper is required for oncogenic BRAF signalling and tumorigenesis DC Brady, MS Crowe, ML Turski, GA Hobbs, X Yao, A Chaikuad, S Knapp, ... Nature 509 (7501), 492-496, 2014	583	2014
Bromodomains as therapeutic targets S Muller, P Filippakopoulos, S Knapp Expert reviews in molecular medicine 13, e29, 2011	567	2011
Large-scale structural analysis of the classical human protein tyrosine phosphatome AJ Barr, E Ugochukwu, WH Lee, ONF King, P Filippakopoulos, I Alfano, ... Cell 136 (2), 352-363, 2009	562	2009
Linear motif atlas for phosphorylation-dependent signaling ML Miller, LJ Jensen, F Diella, C Jørgensen, M Tinti, L Li, M Hsiung, ... Science signaling 1 (35), ra2-ra2, 2008	532	2008
Small-molecule inhibition of BRDT for male contraception MM Matzuk, MR McKeown, P Filippakopoulos, Q Li, L Ma, JE Agno, ... Cell 150 (4), 673-684, 2012	528	2012
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain S Picaud, C Wells, I Felletar, D Brotherton, S Martin, P Savitsky, ... Proceedings of the National Academy of Sciences 110 (49), 19754-19759, 2013	512	2013
The bromodomain interaction module P Filippakopoulos, S Knapp FEBS letters 586 (17), 2692-2704, 2012	470	2012
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ... Nature 508 (7495), 222-227, 2014	455	2014
Exploration of type II binding mode: A privileged approach for kinase inhibitor focused drug discovery? Z Zhao, H Wu, L Wang, Y Liu, S Knapp, Q Liu, NS Gray ACS chemical biology 9 (6), 1230-1241, 2014	443	2014
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers L Brault, C Gasser, F Bracher, K Huber, S Knapp, J Schwaller haematologica 95 (6), 1004, 2010	440	2010
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases O Fedorov, B Marsden, V Pogacic, P Rellos, S Müller, AN Bullock, ... Proceedings of the National Academy of Sciences 104 (51), 20523-20528, 2007	424	2007
Crystal structure of the tetrameric Mad1–Mad2 core complex: implications of a ‘safety belt’binding mechanism for the spindle checkpoint L Sironi, M Mapelli, S Knapp, A De Antoni, KT Jeang, A Musacchio The EMBO journal, 2002	394	2002

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