| Ru (II) compounds: next-generation anticancer metallotherapeutics? S Thota, DA Rodrigues, DC Crans, EJ Barreiro Journal of medicinal chemistry 61 (14), 5805-5821, 2018 | 454 | 2018 |
| N-Acylhydrazones as drugs S Thota, DA Rodrigues, PSM Pinheiro, LM Lima, CAM Fraga, EJ Barreiro Bioorganic & medicinal chemistry letters 28 (17), 2797-2806, 2018 | 189 | 2018 |
| Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors DA Rodrigues, GÀ Ferreira-Silva, ACS Ferreira, RA Fernandes, JK Kwee, ... Journal of medicinal chemistry 59 (2), 655-670, 2016 | 125 | 2016 |
| Duvelisib: a 2018 novel FDA-approved small molecule inhibiting phosphoinositide 3-kinases DA Rodrigues, FS Sagrillo, CAM Fraga Pharmaceuticals 12 (2), 69, 2019 | 70 | 2019 |
| Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities DA Rodrigues, PSM Pinheiro, FS Sagrillo, ML Bolognesi, CAM Fraga Medicinal research reviews 40 (6), 2177-2211, 2020 | 59 | 2020 |
| Synthesis, characterization, DNA binding, DNA cleavage, protein binding and cytotoxic activities of Ru (II) complexes S Thota, S Vallala, R Yerra, DA Rodrigues, NM Raghavendra, EJ Barreiro International Journal of Biological Macromolecules 82, 663-670, 2016 | 44 | 2016 |
| The use of conformational restriction in medicinal chemistry P de Sena M Pinheiro, DA Rodrigues, R do Couto Maia, S Thota, ... Current topics in medicinal chemistry 19 (19), 1712-1733, 2019 | 42 | 2019 |
| Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors DA Rodrigues, FS Guerra, FS Sagrillo, P de Sena M. Pinheiro, MA Alves, ... ChemMedChem 15 (6), 539-551, 2020 | 39 | 2020 |
| The path to venetoclax resistance is paved with mutations, metabolism, and more GP Sullivan, L Flanagan, DA Rodrigues, T Ní Chonghaile Science Translational Medicine 14 (674), eabo6891, 2022 | 26 | 2022 |
| Beyond the selective inhibition of histone deacetylase 6 D A. Rodrigues, S Thota, C AM Fraga Mini Reviews in Medicinal Chemistry 16 (14), 1175-1184, 2016 | 21 | 2016 |
| Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and future prospects DA Rodrigues, PSM Pinheiro, CAM Fraga ChemMedChem 16 (3), 448-457, 2021 | 20 | 2021 |
| Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40) DA Rodrigues, PSM Pinheiro, TTSC Ferreira, S Thota, CAM Fraga Chemical Biology & Drug Design 91 (3), 668-680, 2018 | 19 | 2018 |
| Theoretical and experimental characterization of 1, 4-N⋯ S σ-hole intramolecular interactions in bioactive N-acylhydrazone derivatives PSM Pinheiro, DA Rodrigues, MA Alves, LW Tinoco, GB Ferreira, ... New Journal of Chemistry 42 (1), 497-505, 2018 | 18 | 2018 |
| Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound TF Gomes, TET Pompeu, DA Rodrigues, F Noël, R Menegatti, ... European Journal of Medicinal Chemistry 62, 214-221, 2013 | 17 | 2013 |
| An unusual intramolecular halogen bond guides conformational selection R Tesch, C Becker, MP Müller, ME Beck, L Quambusch, M Getlik, ... Angewandte Chemie International Edition 57 (31), 9970-9975, 2018 | 15 | 2018 |
| Advances in the design and development of PROTAC-mediated HDAC degradation DA Rodrigues, A Roe, D Griffith, TN Chonghaile Current Topics in Medicinal Chemistry 22 (5), 408-424, 2022 | 13 | 2022 |
| Novel single inhibitor of HDAC6/8 and dual inhibitor of PI3K/HDAC6 as potential alternative treatments for prostate cancer FS Guerra, DA Rodrigues, CAM Fraga, PD Fernandes Pharmaceuticals 14 (5), 387, 2021 | 13 | 2021 |
| Recent advances in development of polyphenols as anticancer agents S Thota, DA Rodrigues, EJ Barreiro Mini Reviews in Medicinal Chemistry 18 (15), 1265-1269, 2018 | 13 | 2018 |
| Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC H Zhang, CS Nabel, D Li, RÍ O’Connor, CR Crosby, SM Chang, Y Hao, ... Journal of Thoracic Oncology 18 (7), 882-895, 2023 | 7 | 2023 |
| Modeling zinc‐oxygen coordination in histone deacetylase: a comparison of semiempirical methods performance PSM Pinheiro, DA Rodrigues, CMR Sant'Anna, CAM Fraga International Journal of Quantum Chemistry 118 (21), e25720, 2018 | 7 | 2018 |
Carlos Alberto Manssour FragaProfessor de Farmacologia e Química Medicinal, Universidade Federal do Rio de JaneiroEmail yang diverifikasi di ccsdecania.ufrj.br
Pedro de Sena Murteira PinheiroAssistant Professor, Federal University of Rio de JaneiroEmail yang diverifikasi di ufrj.br
Dr. Sreekanth ThotaProfessor (Pharmaceutical Chemistry & Medicinal Chemistry)Email yang diverifikasi di cdts.fiocruz.br
Carlos Mauricio R. Sant AnnaProfessor Titular do Departamento de Química, Universidade Federal Rural do Rio de JaneiroEmail yang diverifikasi di ufrrj.brMarina Amaral AlvesAssistant Professor, Federal University of Rio de Janeiro, BrazilEmail yang diverifikasi di iq.ufrj.br
Marisa IontaUniversidade Federal de AlfenasEmail yang diverifikasi di unifal-mg.edu.br
Tríona Ní ChonghaileRoyal College of Surgeons in IrelandEmail yang diverifikasi di rcsi.ie