Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs D Weidensdorfer, N Stöhr, A Baude, M Lederer, M Köhn, A Schierhorn, ... Rna 15 (1), 104-115, 2009 | 376 | 2009 |
The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer M Lederer, N Bley, C Schleifer, S Hüttelmaier Seminars in cancer biology 29, 3-12, 2014 | 347 | 2014 |
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner S Müller, M Glaß, AK Singh, J Haase, N Bley, T Fuchs, M Lederer, A Dahl, ... Nucleic acids research 47 (1), 375-390, 2019 | 331 | 2019 |
ZBP1 regulates mRNA stability during cellular stress N Stöhr, M Lederer, C Reinke, S Meyer, M Hatzfeld, RH Singer, ... The Journal of cell biology 175 (4), 527-534, 2006 | 228 | 2006 |
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2–dependent RNA granules R White, C Gonsior, EM Krämer-Albers, N Stöhr, S Hüttelmaier, ... The Journal of cell biology 181 (4), 579-586, 2008 | 223 | 2008 |
Insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma T Gutschner, M Hämmerle, N Pazaitis, N Bley, E Fiskin, H Uckelmann, ... Hepatology 59 (5), 1900-1911, 2014 | 206 | 2014 |
Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming H Berndt, C Harnisch, C Rammelt, N Stöhr, A Zirkel, JC Dohm, ... Rna 18 (5), 958-972, 2012 | 187 | 2012 |
UNR/CSDE1 drives a post-transcriptional program to promote melanoma invasion and metastasis L Wurth, P Papasaikas, D Olmeda, N Bley, GT Calvo, S Guerrero, ... Cancer cell 30 (5), 694-707, 2016 | 169 | 2016 |
IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling N Stöhr, M Köhn, M Lederer, M Glaß, C Reinke, RH Singer, S Hüttelmaier Genes & development 26 (2), 176-189, 2012 | 161 | 2012 |
Stress granules are dispensable for mRNA stabilization during cellular stress N Bley, M Lederer, B Pfalz, C Reinke, T Fuchs, M Glaß, B Möller, ... Nucleic acids research 43 (4), e26-e26, 2015 | 155 | 2015 |
The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family B Busch, N Bley, S Müller, M Glaß, D Misiak, M Lederer, M Vetter, ... Nucleic acids research 44 (8), 3845-3864, 2016 | 132 | 2016 |
The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer S Müller, N Bley, B Busch, M Glaß, M Lederer, C Misiak, T Fuchs, ... Nucleic acids research 48 (15), 8576-8590, 2020 | 131 | 2020 |
IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors S Müller, N Bley, M Glaß, B Busch, V Rousseau, D Misiak, T Fuchs, ... Nucleic acids research 46 (12), 6285-6303, 2018 | 131 | 2018 |
Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains K Wächter, M Köhn, N Stöhr, S Hüttelmaier Biological chemistry 394 (8), 1077-1090, 2013 | 129 | 2013 |
IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG) A Zirkel, M Lederer, N Stöhr, N Pazaitis, S Hüttelmaier Nucleic acids research 41 (13), 6618-6636, 2013 | 72 | 2013 |
IGF2BP1: a post-transcriptional “driver” of tumor cell migration N Stöhr, S Hüttelmaier Cell Adhesion & Migration 6 (4), 312-318, 2012 | 62 | 2012 |
Endocytotic internalization as a crucial factor for the cytotoxicity of ribonucleases F Leich, N Stohr, A Rietz, R Ulbrich-Hofmann, U Arnold Journal of Biological Chemistry 282 (38), 27640-27646, 2007 | 54 | 2007 |
IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer N Bley, A Schott, S Müller, D Misiak, M Lederer, T Fuchs, C Aßmann, ... RNA biology 18 (3), 391-403, 2021 | 37 | 2021 |
IGF2BP1, a conserved regulator of RNA turnover in cancer M Glaß, D Misiak, N Bley, S Müller, S Hagemann, B Busch, A Rausch, ... Frontiers in Molecular Biosciences 8, 632219, 2021 | 36 | 2021 |
Arginine methylation of the nuclear poly (a) binding protein weakens the interaction with its nuclear import receptor, transportin K Fronz, S Güttinger, K Burkert, U Kühn, N Stöhr, A Schierhorn, E Wahle Journal of Biological Chemistry 286 (38), 32986-32994, 2011 | 35 | 2011 |