Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2783 | 2018 |
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 2403 | 2013 |
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults EB Binder, RG Bradley, W Liu, MP Epstein, TC Deveau, KB Mercer, ... Jama 299 (11), 1291-1305, 2008 | 1755 | 2008 |
Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions T Klengel, D Mehta, C Anacker, M Rex-Haffner, JC Pruessner, ... Nature neuroscience 16 (1), 33-41, 2013 | 1610 | 2013 |
Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics C Heim, EB Binder Experimental neurology 233 (1), 102-111, 2012 | 1301 | 2012 |
A mega-analysis of genome-wide association studies for major depressive disorder Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Molecular psychiatry 18 (4), 10.1038/mp. 2012.21, 2012 | 1282 | 2012 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1152 | 2019 |
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment EB Binder, D Salyakina, P Lichtner, GM Wochnik, M Ising, B Pütz, ... Nature genetics 36 (12), 1319-1325, 2004 | 1143 | 2004 |
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders EB Binder Psychoneuroendocrinology 34, S186-S195, 2009 | 1083 | 2009 |
Holocaust exposure induced intergenerational effects on FKBP5 methylation R Yehuda, NP Daskalakis, LM Bierer, HN Bader, T Klengel, F Holsboer, ... Biological psychiatry 80 (5), 372-380, 2016 | 1033 | 2016 |
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor KJ Ressler, KB Mercer, B Bradley, T Jovanovic, A Mahan, K Kerley, ... Nature 470 (7335), 492-497, 2011 | 902 | 2011 |
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene RG Bradley, EB Binder, MP Epstein, Y Tang, HP Nair, W Liu, CF Gillespie, ... Archives of general psychiatry 65 (2), 190-200, 2008 | 898 | 2008 |
The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology EI Martin, KJ Ressler, E Binder, CB Nemeroff Clinics in laboratory medicine 30 (4), 865-891, 2010 | 869 | 2010 |
Epigenetic signatures of cigarette smoking R Joehanes, AC Just, RE Marioni, LC Pilling, LM Reynolds, ... Circulation: cardiovascular genetics 9 (5), 436-447, 2016 | 857 | 2016 |
Identification of common variants associated with human hippocampal and intracranial volumes JL Stein, SE Medland, AA Vasquez, DP Hibar, RE Senstad, AM Winkler, ... Nature genetics 44 (5), 552-561, 2012 | 719 | 2012 |
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data PM Thompson, JL Stein, SE Medland, DP Hibar, AA Vasquez, ... Brain imaging and behavior 8, 153-182, 2014 | 705 | 2014 |
The transcriptional landscape of age in human peripheral blood MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ... Nature communications 6 (1), 1-14, 2015 | 650 | 2015 |
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder D Mehta, T Klengel, KN Conneely, AK Smith, A Altmann, TW Pace, ... Proceedings of the national academy of sciences 110 (20), 8302-8307, 2013 | 642 | 2013 |
Assessment of bidirectional relationships between physical activity and depression among adults: a 2-sample Mendelian randomization study KW Choi, CY Chen, MB Stein, YC Klimentidis, MJ Wang, KC Koenen, ... JAMA psychiatry 76 (4), 399-408, 2019 | 588 | 2019 |
Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications AS Zannas, T Wiechmann, NC Gassen, EB Binder Neuropsychopharmacology 41 (1), 261-274, 2016 | 576 | 2016 |