A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability RD Paulsen, DV Soni, R Wollman, AT Hahn, MC Yee, A Guan, JA Hesley, ... Molecular cell 35 (2), 228-239, 2009 | 629 | 2009 |
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality DA Chan, PD Sutphin, P Nguyen, S Turcotte, EW Lai, A Banh, ... Science translational medicine 3 (94), 94ra70-94ra70, 2011 | 620 | 2011 |
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma I Papandreou, NC Denko, M Olson, H Van Melckebeke, S Lust, A Tam, ... Blood, The Journal of the American Society of Hematology 117 (4), 1311-1314, 2011 | 552 | 2011 |
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension E Spiekerkoetter, X Tian, J Cai, RK Hopper, D Sudheendra, CG Li, ... The Journal of clinical investigation 123 (8), 3600-3613, 2013 | 488 | 2013 |
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade JM Hyman, AJ Firestone, VM Heine, Y Zhao, CA Ocasio, K Han, M Sun, ... Proceedings of the National Academy of Sciences 106 (33), 14132-14137, 2009 | 365 | 2009 |
Methods of treating conditions associated with an Edg-3 receptor G Shankar, D Solow-Cordero, J Spencer, C Gluchowski US Patent App. 10/760,064, 2004 | 266* | 2004 |
Transforming growth factor-β regulation of bone morphogenetic protein-1/procollagen C-proteinase and related proteins in fibrogenic cells and keratinocytes S Lee, DE Solow-Cordero, E Kessler, K Takahara, DS Greenspan Journal of Biological Chemistry 272 (30), 19059-19066, 1997 | 155 | 1997 |
A small-molecule antivirulence agent for treating Clostridium difficile infection KO Bender, M Garland, JA Ferreyra, AJ Hryckowian, MA Child, AW Puri, ... Science translational medicine 7 (306), 306ra148-306ra148, 2015 | 142 | 2015 |
RNA cleavage and chain elongation by Escherichia coli DNA-dependent RNA polymerase in a binary enzyme. RNA complex. CR Altmann, DE Solow-Cordero, MJ Chamberlin Proceedings of the National Academy of Sciences 91 (9), 3784-3788, 1994 | 93 | 1994 |
Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens CJ Matheny, MC Wei, MC Bassik, AJ Donnelly, M Kampmann, M Iwasaki, ... Chemistry & biology 20 (11), 1352-1363, 2013 | 91 | 2013 |
A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide H Fan-Minogue, S Bodapati, D Solow-Cordero, A Fan, R Paulmurugan, ... Molecular cancer therapeutics 12 (9), 1896-1905, 2013 | 57 | 2013 |
A C-terminal deletion in Corynebacterium glutamicum homoserine dehydrogenase abolishes allosteric inhibition by L-threonine JAC Archer, DE Solow-Cordero, AJ Sinskey Gene 107 (1), 53-59, 1991 | 57 | 1991 |
Identification of new drug candidates against Borrelia burgdorferi using high-throughput screening VR Pothineni, D Wagh, MM Babar, M Inayathullah, D Solow-Cordero, ... Drug Design, Development and Therapy, 1307-1322, 2016 | 56 | 2016 |
FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension S Dannewitz Prosseda, X Tian, K Kuramoto, M Boehm, D Sudheendra, ... American journal of respiratory and critical care medicine 199 (1), 83-98, 2019 | 51 | 2019 |
High-Throughput Screening of Entamoeba Identifies Compounds Which Target Both Life Cycle Stages and Which Are Effective Against Metronidazole Resistant … GM Ehrenkaufer, S Suresh, D Solow-Cordero, U Singh Frontiers in cellular and infection microbiology 8, 276, 2018 | 49 | 2018 |
A high-throughput system to identify inhibitors of Candidatus Liberibacter asiaticus transcription regulators MJ Barnett, DE Solow-Cordero, SR Long Proceedings of the National Academy of Sciences 116 (36), 18009-18014, 2019 | 45 | 2019 |
Acridine derivatives as inhibitors of the ire1α–xbp1 pathway are cytotoxic to human multiple myeloma D Jiang, AB Tam, M Alagappan, MP Hay, A Gupta, MM Kozak, ... Molecular cancer therapeutics 15 (9), 2055-2065, 2016 | 37 | 2016 |
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects CT Chan, RE Reeves, R Geller, SS Yaghoubi, A Hoehne, ... Proceedings of the National Academy of Sciences 109 (37), E2476-E2485, 2012 | 34 | 2012 |
Molecular imaging of phosphorylation events for drug development CT Chan, R Paulmurugan, RE Reeves, D Solow-Cordero, SS Gambhir Molecular imaging and biology 11, 144-158, 2009 | 32 | 2009 |
Therapeutic Targeting of BRCA1-Mutated Breast Cancers with Agents That Activate DNA Repair E Alli, D Solow-Cordero, SC Casey, JM Ford Cancer research 74 (21), 6205-6215, 2014 | 27 | 2014 |