Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities XQ Li, TB Andersson, M Ahlström, L Weidolf Drug metabolism and disposition 32 (8), 821-827, 2004 | 968 | 2004 |
Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes A Äbelö, TB Andersson, M Antonsson, AK Naudot, I Skånberg, L Weidolf Drug Metabolism and Disposition 28 (8), 966-972, 2000 | 498 | 2000 |
Pharmacokinetic Studies with Esomeprazole, the (S)-Isomer of Omeprazole T Andersson, M Hassan-Alin, G Hasselgren, K Röhss, L Weidolf Clinical pharmacokinetics 40, 411-426, 2001 | 351 | 2001 |
Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies EM Isin, CS Elmore, GN Nilsson, RA Thompson, L Weidolf Chemical research in toxicology 25 (3), 532-542, 2012 | 284 | 2012 |
In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs RA Thompson, EM Isin, Y Li, L Weidolf, K Page, I Wilson, S Swallow, ... Chemical research in toxicology 25 (8), 1616-1632, 2012 | 238 | 2012 |
Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions U Jurva, HV Wikström, L Weidolf, AP Bruins Rapid communications in mass spectrometry 17 (8), 800-810, 2003 | 232 | 2003 |
Determination of sulfonated azo dyes by liquid chromatography/atmospheric pressure ionization mass spectrometry AP Bruins, LOG Weidolf, JD Henion, WL Budde Analytical Chemistry 59 (22), 2647-2652, 1987 | 161 | 1987 |
Mimicry of phase I drug metabolism–novel methods for metabolite characterization and synthesis T Johansson, L Weidolf, U Jurva Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 158 | 2007 |
State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applications L Afzelius, C Hasselgren Arnby, A Broo, L Carlsson, C Isaksson, U Jurva, ... Drug metabolism reviews 39 (1), 61-86, 2007 | 153 | 2007 |
Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole P Lindberg, L Weidolf US Patent 5,877,192, 1999 | 132 | 1999 |
Determination of boldenone sulfoconjugate and related steroid sulfates in equine urine by high‐performance liquid chromatography/tandem mass spectrometry LOG Weidolf, ED Lee, JD Henion Biomedical & environmental mass spectrometry 15 (5), 283-289, 1988 | 122 | 1988 |
Stereoselective disposition of proton pump inhibitors T Andersson, L Weidolf Clinical Drug Investigation 28, 263-279, 2008 | 112 | 2008 |
Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development RA Thompson, EM Isin, Y Li, R Weaver, L Weidolf, I Wilson, A Claesson, ... Chemico-biological interactions 192 (1-2), 65-71, 2011 | 101 | 2011 |
Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens L Hagvall, JM Baron, A Börje, L Weidolf, H Merk, AT Karlberg Toxicology and applied pharmacology 233 (2), 308-313, 2008 | 93 | 2008 |
In vitro metabolism of haloperidol and sila-haloperidol: new metabolic pathways resulting from carbon/silicon exchange T Johansson, L Weidolf, F Popp, R Tacke, U Jurva Drug metabolism and disposition 38 (1), 73-83, 2010 | 86 | 2010 |
In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system M Darnell, M Ulvestad, E Ellis, L Weidolf, TB Andersson Journal of Pharmacology and Experimental Therapeutics 343 (1), 134-144, 2012 | 81 | 2012 |
Novel metabolites of amodiaquine formed by CYP1A1 and CYP1B1: structure elucidation using electrochemistry, mass spectrometry, and NMR T Johansson, U Jurva, G Grönberg, L Weidolf, C Masimirembwa Drug metabolism and disposition 37 (3), 571-579, 2009 | 77 | 2009 |
Stereoselective metabolism by human liver CYP enzymes of a substituted benzimidazole A Äbelö, TB Andersson, ULF Bredberg, I Skånberg, L Weidolf Drug metabolism and disposition 28 (1), 58-64, 2000 | 71 | 2000 |
Metabolism of xenobiotic carboxylic acids: focus on coenzyme A conjugation, reactivity, and interference with lipid metabolism M Darnell, L Weidolf Chemical research in toxicology 26 (8), 1139-1155, 2013 | 69 | 2013 |
Pharmacokinetics (PK) and effect on pentagastrin stimulated peak acid output (PAO) of omeprazole (O) and its 2 optical isomers, S-omeprazole/esomeprazole (E) and R-omeprazole (RO) T Andersson, E Bredberg, M Sunzel, M Antonsson, L Weidolf Gastroenterology 4 (118), A1210, 2000 | 64 | 2000 |