Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis DA Rodriguez, R Weinlich, S Brown, C Guy, P Fitzgerald, CP Dillon, ... Cell Death & Differentiation 23 (1), 76-88, 2016 | 375 | 2016 |
Identification of gangliosides GD1b and GT1b as receptors for BK virus JA Low, B Magnuson, B Tsai, MJ Imperiale Journal of virology 80 (3), 1361-1366, 2006 | 285 | 2006 |
Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia ML Churchman, J Low, C Qu, EM Paietta, LH Kasper, Y Chang, ... Cancer cell 28 (3), 343-356, 2015 | 208 | 2015 |
BKV and SV40 infection of human kidney tubular epithelial cells in vitro J Low, HD Humes, M Szczypka, M Imperiale Virology 323 (2), 182-188, 2004 | 165 | 2004 |
Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer MT McCabe, JA Low, S Daignault, MJ Imperiale, KJ Wojno, ML Day Cancer research 66 (1), 385-392, 2006 | 146 | 2006 |
Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors W Ittarat, AL Pickard, P Rattanasinganchan, P Wilairatana, ... The American journal of tropical medicine and hygiene 68 (2), 147-152, 2003 | 136 | 2003 |
Role for the adenovirus IVa2 protein in packaging of viral DNA W Zhang, JA Low, JB Christensen, MJ Imperiale Journal of virology 75 (21), 10446-10454, 2001 | 130 | 2001 |
Inhibitory effect of gamma interferon on BK virus gene expression and replication JR Abend, JA Low, MJ Imperiale Journal of virology 81 (1), 272-279, 2007 | 121 | 2007 |
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 107 | 2017 |
Identification of small molecule activators of BMP signaling K Vrijens, W Lin, J Cui, D Farmer, J Low, E Pronier, FY Zeng, AA Shelat, ... PloS one 8 (3), e59045, 2013 | 90 | 2013 |
Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway MT McCabe, JA Low, MJ Imperiale, ML Day Oncogene 25 (19), 2727-2735, 2006 | 79 | 2006 |
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma M Pan, WC Wright, RH Chapple, A Zubair, M Sandhu, JE Batchelder, ... Nature communications 12 (1), 6468, 2021 | 62 | 2021 |
Global effects of BKV infection on gene expression in human primary kidney epithelial cells JR Abend, JA Low, MJ Imperiale Virology 397 (1), 73-79, 2010 | 58 | 2010 |
Targeting histone demethylases in MYC-driven neuroblastomas with ciclopirox J Yang, S Milasta, D Hu, AM AlTahan, RB Interiano, J Zhou, J Davidson, ... Cancer research 77 (17), 4626-4638, 2017 | 53 | 2017 |
High-content imaging characterization of cell cycle therapeutics through in vitro and in vivo subpopulation analysis J Low, S Huang, W Blosser, M Dowless, J Burch, B Neubauer, L Stancato Molecular cancer therapeutics 7 (8), 2455-2463, 2008 | 38 | 2008 |
The isoniazid metabolites hydrazine and pyridoxal isonicotinoyl hydrazone modulate heme biosynthesis CT Brewer, L Yang, A Edwards, Y Lu, J Low, J Wu, RE Lee, T Chen Toxicological Sciences 168 (1), 209-224, 2019 | 37 | 2019 |
Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer PJ Slavish, L Chi, MK Yun, L Tsurkan, NE Martinez, B Jonchere, SC Chai, ... Cancer research 80 (17), 3507-3518, 2020 | 36 | 2020 |
A robust high-content imaging approach for probing the mechanism of action and phenotypic outcomes of cell-cycle modulators JJ Sutherland, J Low, W Blosser, M Dowless, TA Engler, LF Stancato Molecular cancer therapeutics 10 (2), 242-254, 2011 | 34 | 2011 |
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors JM Barajas, M Rasouli, M Umeda, R Hiltenbrand, S Abdelhamed, ... Blood 143 (7), 619-630, 2024 | 33 | 2024 |
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition Y Drosos, JA Myers, B Xu, KM Mathias, EC Beane, S Radko-Juettner, ... Molecular cell 82 (13), 2472-2489. e8, 2022 | 33 | 2022 |