| High levels of AAV vector integration into CRISPR-induced DNA breaks KS Hanlon, BP Kleinstiver, SP Garcia, MP Zaborowski, A Volak, SE Spirig, ... Nature communications 10 (1), 4439, 2019 | 387 | 2019 |
| Selection of an efficient AAV vector for robust CNS transgene expression KS Hanlon, JC Meltzer, T Buzhdygan, MJ Cheng, M Sena-Esteves, ... Molecular Therapy Methods & Clinical Development 15, 320-332, 2019 | 151 | 2019 |
| Gene transfer with AAV9-PHP. B rescues hearing in a mouse model of usher syndrome 3A and transduces hair cells in a non-human primate B György, EJ Meijer, MV Ivanchenko, K Tenneson, F Emond, KS Hanlon, ... Molecular therapy Methods & clinical development 13, 1-13, 2019 | 149 | 2019 |
| Genomic investigations of unexplained acute hepatitis in children S Morfopoulou, S Buddle, OE Torres Montaguth, L Atkinson, ... Nature 617 (7961), 564-573, 2023 | 107 | 2023 |
| Preclinical testing of AAV9-PHP. B for transgene expression in the non-human primate cochlea MV Ivanchenko*, KS Hanlon*, MK Devine, K Tenneson, F Emond, ... Hearing Research, 107930, 2020 | 53 | 2020 |
| AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear MV Ivanchenko, KS Hanlon, DM Hathaway, AJ Klein, CW Peters, Y Li, ... Molecular Therapy Methods & Clinical Development 21, 382-398, 2021 | 51 | 2021 |
| In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery CB Breuer, KS Hanlon, J Natasan, A Volak, A Meliani, F Mingozzi, ... Scientific Reports 10 (1), 4544, 2020 | 31 | 2020 |
| Delivering AAV to the central nervous and sensory systems CW Peters, CA Maguire, KS Hanlon Trends in pharmacological sciences 42 (6), 461-474, 2021 | 30 | 2021 |
| A novel retinal ganglion cell promoter for utility in AAV vectors KS Hanlon, N Chadderton, A Palfi, A Blanco Fernandez, P Humphries, ... Frontiers in Neuroscience 11, 521, 2017 | 29 | 2017 |
| The AAV9 variant capsid AAV-F mediates widespread transgene expression in nonhuman primate spinal cord after intrathecal administration A Beharry, Y Gong, JC Kim, KS Hanlon, J Nammour, K Hieber, F Eichler, ... Human Gene Therapy 33 (1-2), 61-75, 2022 | 21 | 2022 |
| Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F CW Peters, KS Hanlon, MV Ivanchenko, E Zinn, EF Linarte, Y Li, JM Levy, ... Molecular Therapy 31 (8), 2439-2453, 2023 | 19 | 2023 |
| Versatile Role Of Rab27a In Glioma: Effects On Release Of Extracellular Vesicles, Cell Viability And Tumor Progression TS Van Solinge, ER Abels, LL Van De Haar, KS Hanlon, SLN Maas, ... Frontiers in molecular biosciences 7, 324, 2020 | 16 | 2020 |
| An engineered adeno-associated virus capsid mediates efficient transduction of pericytes and smooth muscle cells of the brain vasculature SH Ramirez, JF Hale, S McCarthy, CL Lino Cardenas, KNUG Dona, ... Human Gene Therapy 34 (15-16), 682-696, 2023 | 12 | 2023 |
| Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells S Millington-Ward, N Chadderton, M Berkeley, LK Finnegan, KS Hanlon, ... Scientific Reports 10 (1), 16515, 2020 | 12 | 2020 |
| Optimisation of AAV-NDI1 significantly enhances its therapeutic value for correcting retinal mitochondrial dysfunction N Chadderton, A Palfi, DM Maloney, M Carrigan, LK Finnegan, ... Pharmaceutics 15 (2), 322, 2023 | 6 | 2023 |
| In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord KS Hanlon, M Cheng, RM Ferrer, JR Ryu, B Lee, D De La Cruz, N Patel, ... Molecular Therapy 32 (8), 2584-2603, 2024 | 3 | 2024 |
| Engineered adeno-associated (aav) vectors for transgene expression CA Maguire, EM Hudry, KS Hanlon US Patent App. 17/442,894, 2022 | 2 | 2022 |
| In vivo selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord KS Hanlon, M Cheng, D De La Cruz, N Patel, MC Santoscoy, Y Gong, ... bioRxiv, 2023 | 1 | 2023 |
| Recombinant adeno associated virus encoding clarin-1 and uses thereof DP Corey, CA Maguire, KS Hanlon, MV Ivanchenko US Patent 12,129,287, 2024 | | 2024 |
| Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice MC Santoscoy, P Espinoza, KS Hanlon, L Yang, L Nieland, C Ng, ... bioRxiv, 2024 | | 2024 |