| Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA. YC Tse, K Kirkegaard, JC Wang Journal of Biological Chemistry 255 (12), 5560-5565, 1980 | 391 | 1980 |
| Direct observation of DNA distortion by the RSC complex G Lia, E Praly, H Ferreira, C Stockdale, YC Tse-Dinh, D Dunlap, ... Molecular cell 21 (3), 417-425, 2006 | 187 | 2006 |
| Regulation of the Escherichia coli DNA topoisomerase I gene by DNA supercolling YC Tse-Dinh Nucleic acids research 13 (13), 4751-4763, 1985 | 167 | 1985 |
| E. coli and M. luteus DNA topoisomerase I can catalyze catenation or decatenation of double-stranded DNA rings Y Tse, JC Wang Cell 22 (1), 269-276, 1980 | 149 | 1980 |
| Escherichia coli DNA topoisomerase I is a zinc metalloprotein with three repetitive zinc-binding domains. YC Tse-Dinh, RK Beran-Steed Journal of Biological Chemistry 263 (31), 15857-15859, 1988 | 131 | 1988 |
| Bacterial topoisomerase I as a target for discovery of antibacterial compounds YC Tse-Dinh Nucleic acids research 37 (3), 731-737, 2009 | 127 | 2009 |
| Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I YC Tse-Dinh, JC Wang Journal of molecular biology 191 (3), 321-331, 1986 | 125 | 1986 |
| Direct interaction between Escherichia coli RNA polymerase and the zinc ribbon domains of DNA topoisomerase I B Cheng, CX Zhu, C Ji, A Ahumada, YC Tse-Dinh Journal of Biological Chemistry 278 (33), 30705-30710, 2003 | 118 | 2003 |
| Multiple promoters for transcription of the Escherichia coli DNA topoisomerase I gene and their regulation by DNA supercoiling YC Tse-Dinh, RK Beran Journal of molecular biology 202 (4), 735-742, 1988 | 118 | 1988 |
| Synthesis, structure–activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives L Feng, MM Maddox, MZ Alam, LS Tsutsumi, G Narula, DF Bruhn, X Wu, ... Journal of medicinal chemistry 57 (20), 8398-8420, 2014 | 117 | 2014 |
| Holliday junction crossover topology TJ Fu, YC Tse-Dinh, NC Seeman Journal of molecular biology 236 (1), 91-105, 1994 | 116 | 1994 |
| DNA supercoiling and bacterial adaptation: thermotolerance and thermoresistance YC Tse-Dinh, Q Haiyan, R Menzel Trends in microbiology 5 (8), 323-326, 1997 | 112 | 1997 |
| Backbone dynamics of the C-terminal domain of Escherichia coli topoisomerase I in the absence and presence of single-stranded DNA L Yu, CX Zhu, YC Tse-Dinh, SW Fesik Biochemistry 35 (30), 9661-9666, 1996 | 104 | 1996 |
| Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases YC Tse-Dinh Infectious Disorders-Drug TargetsDisorders) 7 (1), 3-9, 2007 | 101 | 2007 |
| Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I Z Zhang, B Cheng, YC Tse-Dinh Proceedings of the National Academy of Sciences 108 (17), 6939-6944, 2011 | 88 | 2011 |
| Virus- and cell-encoded tyrosine protein kinases inactivate DNA topoisomerases in vitro YC Tse-Dinh, TW Wong, AR Goldberg Nature 312 (5996), 785-786, 1984 | 85 | 1984 |
| The acidic triad conserved in type IA DNA topoisomerases is required for binding of MG (II) and subsequent conformational change CX Zhu, YC Tse-Dinh Journal of Biological Chemistry 275 (8), 5318-5322, 2000 | 77 | 2000 |
| Topoisomerase function during bacterial responses to environmental challenge S Rui, YC Tse-Dinh Front Biosci 8, d256-d263, 2003 | 76 | 2003 |
| Bacterial and archeal type I topoisomerases YC Tse-Dinh Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1400 (1-3 …, 1998 | 76 | 1998 |
| Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I K Tan, Q Zhou, B Cheng, Z Zhang, A Joachimiak, YC Tse-Dinh Nucleic acids research 43 (22), 11031-11046, 2015 | 73 | 2015 |
Purushottam TiwariGeorgetown UniversityEmail yang diverifikasi di georgetown.edu
