| Heart disease and stroke statistics—2016 update: a report from the American Heart Association D Mozaffarian, EJ Benjamin, AS Go, DK Arnett, MJ Blaha, M Cushman, ... circulation 133 (4), e38-e360, 2016 | 48834* | 2016 |
| An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium Nature 489 (7414), 57, 2012 | 17596 | 2012 |
| Heart disease and stroke statistics—2014 update: a report from the American Heart Association AS Go, D Mozaffarian, VL Roger, EJ Benjamin, JD Berry, MJ Blaha, S Dai, ... circulation 129 (3), e28-e292, 2014 | 13667* | 2014 |
| A map of human genome variation from population scale sequencing 1000 Genomes Project Consortium Nature 467 (7319), 1061, 2010 | 9067 | 2010 |
| An integrated map of genetic variation from 1,092 human genomes 1000 Genomes Project Consortium Nature 491 (7422), 56, 2012 | 8642 | 2012 |
| A user's guide to the encyclopedia of DNA elements (ENCODE) ENCODE Project Consortium PLoS biology 9 (4), e1001046, 2011 | 1499 | 2011 |
| The genomic complexity of primary human prostate cancer MF Berger, MS Lawrence, F Demichelis, Y Drier, K Cibulskis, ... Nature 470 (7333), 214-220, 2011 | 1470 | 2011 |
| Personal omics profiling reveals dynamic molecular and medical phenotypes R Chen, GI Mias, J Li-Pook-Than, L Jiang, HYK Lam, R Chen, E Miriami, ... Cell 148 (6), 1293-1307, 2012 | 1436 | 2012 |
| A systematic survey of loss-of-function variants in human protein-coding genes DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, ... Science 335 (6070), 823-828, 2012 | 1428 | 2012 |
| Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project MB Gerstein, ZJ Lu, EL Van Nostrand, C Cheng, BI Arshinoff, T Liu, ... Science 330 (6012), 1775-1787, 2010 | 1159 | 2010 |
| Computationally efficient whole-genome regression for quantitative and binary traits J Mbatchou, L Barnard, J Backman, A Marcketta, JA Kosmicki, ... Nature genetics 53 (7), 1097-1103, 2021 | 969 | 2021 |
| Genetic and pharmacologic inactivation of ANGPTL3 and cardiovascular disease FE Dewey, V Gusarova, RL Dunbar, C O’Dushlaine, C Schurmann, ... New England Journal of Medicine 377 (3), 211-221, 2017 | 841 | 2017 |
| Assessment of transcript reconstruction methods for RNA-seq T Steijger, JF Abril, PG Engström, F Kokocinski, TJ Hubbard, R Guigó, ... Nature methods 10 (12), 1177-1184, 2013 | 784 | 2013 |
| Demographic history and rare allele sharing among human populations S Gravel, BM Henn, RN Gutenkunst, AR Indap, GT Marth, AG Clark, F Yu, ... Proceedings of the National Academy of Sciences 108 (29), 11983-11988, 2011 | 747 | 2011 |
| Variation in transcription factor binding among humans M Kasowski, F Grubert, C Heffelfinger, M Hariharan, A Asabere, ... science 328 (5975), 232-235, 2010 | 724 | 2010 |
| Exome sequencing and analysis of 454,787 UK Biobank participants JD Backman, AH Li, A Marcketta, D Sun, J Mbatchou, MD Kessler, ... Nature 599 (7886), 628-634, 2021 | 703 | 2021 |
| Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study FE Dewey, MF Murray, JD Overton, L Habegger, JB Leader, SN Fetterolf, ... Science 354 (6319), aaf6814, 2016 | 584 | 2016 |
| Inactivating variants in ANGPTL4 and risk of coronary artery disease FE Dewey, V Gusarova, C O’Dushlaine, O Gottesman, J Trejos, C Hunt, ... New England Journal of Medicine 374 (12), 1123-1133, 2016 | 524 | 2016 |
| Exome sequencing and characterization of 49,960 individuals in the UK Biobank CV Van Hout, I Tachmazidou, JD Backman, JD Hoffman, D Liu, ... Nature 586 (7831), 749-756, 2020 | 474 | 2020 |
| Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 467 | 2010 |
