| Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors E Song, P Zhu, SK Lee, D Chowdhury, S Kussman, DM Dykxhoorn, ... Nature biotechnology 23 (6), 709-717, 2005 | 1378 | 2005 |
| DNA breaks and chromosome pulverization from errors in mitosis K Crasta, NJ Ganem, R Dagher, AB Lantermann, EV Ivanova, Y Pan, ... Nature 482 (7383), 53-58, 2012 | 1376 | 2012 |
| Death by a thousand cuts: granzyme pathways of programmed cell death D Chowdhury, J Lieberman Annu. Rev. Immunol. 26 (1), 389-420, 2008 | 892 | 2008 |
| Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus MA Lee-Kirsch, M Gong, D Chowdhury, L Senenko, K Engel, YA Lee, ... Nature genetics 39 (9), 1065-1067, 2007 | 782 | 2007 |
| γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair D Chowdhury, MC Keogh, H Ishii, CL Peterson, S Buratowski, ... Molecular cell 20 (5), 801-809, 2005 | 741 | 2005 |
| miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3′ UTR microRNA recognition elements A Lal, F Navarro, CA Maher, LE Maliszewski, N Yan, E O'Day, ... Molecular cell 35 (5), 610-625, 2009 | 703 | 2009 |
| Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade … KC Strickland, BE Howitt, SA Shukla, S Rodig, LL Ritterhouse, JF Liu, ... Oncotarget 7 (12), 13587, 2016 | 637 | 2016 |
| A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery MC Keogh, JA Kim, M Downey, J Fillingham, D Chowdhury, JC Harrison, ... Nature 439 (7075), 497-501, 2006 | 636 | 2006 |
| An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection D Palliser, D Chowdhury, QY Wang, SJ Lee, RT Bronson, DM Knipe, ... Nature 439 (7072), 89-94, 2006 | 571 | 2006 |
| miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors P Moskwa, FM Buffa, Y Pan, R Panchakshari, P Gottipati, RJ Muschel, ... Molecular cell 41 (2), 210-220, 2011 | 520 | 2011 |
| miR-24–mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells A Lal, Y Pan, F Navarro, DM Dykxhoorn, L Moreau, E Meire, Z Bentwich, ... Nature structural & molecular biology 16 (5), 492-498, 2009 | 335 | 2009 |
| The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death D Chowdhury, PJ Beresford, P Zhu, D Zhang, JS Sung, B Demple, ... Molecular cell 23 (1), 133-142, 2006 | 329 | 2006 |
| A PP4-phosphatase complex dephosphorylates γ-H2AX generated during DNA replication D Chowdhury, X Xu, X Zhong, F Ahmed, J Zhong, J Liao, DM Dykxhoorn, ... Molecular cell 31 (1), 33-46, 2008 | 311 | 2008 |
| Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance N Johnson, SF Johnson, W Yao, YC Li, YE Choi, AJ Bernhardy, Y Wang, ... Proceedings of the National Academy of Sciences 110 (42), 17041-17046, 2013 | 273 | 2013 |
| A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus MA Lee-Kirsch, D Chowdhury, S Harvey, M Gong, L Senenko, K Engel, ... Journal of Molecular Medicine 85, 531-537, 2007 | 257 | 2007 |
| Stepwise activation of the immunoglobulin μ heavy chain gene locus D Chowdhury, R Sen The EMBO journal, 2001 | 257 | 2001 |
| Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ... Nature communications 11 (1), 1459, 2020 | 251 | 2020 |
| DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ... Nature 563 (7732), 522-526, 2018 | 215 | 2018 |
| Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial PA Konstantinopoulos, SC Cheng, AEW Hendrickson, RT Penson, ... The Lancet Oncology 21 (7), 957-968, 2020 | 199 | 2020 |
| Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments DGT Hesslein, DL Pflugh, D Chowdhury, ALM Bothwell, R Sen, ... Genes & development 17 (1), 37-42, 2003 | 198 | 2003 |
