Ikuti
Tjakko van Ham
Tjakko van Ham
Head of Diagnostic Laboratory, Dept Clinical Genetics, Erasmus MC, Rotterdam, the Netherlands
Email yang diverifikasi di erasmusmc.nl
Judul
Dikutip oleh
Dikutip oleh
Tahun
C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging
TJ Van Ham, KL Thijssen, R Breitling, RMW Hofstra, RHA Plasterk, ...
PLoS genetics 4 (3), e1000027, 2008
4872008
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration
TM Tsarouchas, D Wehner, L Cavone, T Munir, M Keatinge, M Lambertus, ...
Nature communications 9 (1), 4670, 2018
2662018
Homozygous mutations in CSF1R cause a pediatric-onset leukoencephalopathy and can result in congenital absence of microglia
N Oosterhof, IJ Chang, EG Karimiani, LE Kuil, DM Jensen, R Daza, ...
The American Journal of Human Genetics 104 (5), 936-947, 2019
2292019
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity
TJ van Ham, MA Holmberg, AT van der Goot, E Teuling, ...
Cell 142 (4), 601-612, 2010
1772010
Live imaging of apoptotic cells in zebrafish
TJ van Ham, J Mapes, D Kokel, RT Peterson
The FASEB Journal 24 (11), 4336, 2010
1582010
Colony-stimulating factor 1 receptor (CSF1R) regulates microglia density and distribution, but not microglia differentiation in vivo
N Oosterhof, LE Kuil, HC van der Linde, SM Burm, W Berdowski, ...
Cell reports 24 (5), 1203-1217. e6, 2018
1422018
Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip
C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ...
The EMBO journal 28 (23), 3758-3770, 2009
1382009
Identification of nonvisual photomotor response cells in the vertebrate hindbrain
D Kokel, TW Dunn, MB Ahrens, R Alshut, CYJ Cheung, L Saint-Amant, ...
Journal of Neuroscience 33 (9), 3834-3843, 2013
1362013
Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis
MI Cunha, M Su, L Cantuti-Castelvetri, SA Müller, M Schifferer, ...
Journal of Experimental Medicine 217 (5), e20191390, 2020
1352020
A FRET sensor for non‐invasive imaging of amyloid formation in vivo
GS Kaminski Schierle, CW Bertoncini, FTS Chan, AT Van Der Goot, ...
ChemPhysChem 12 (3), 673-680, 2011
1332011
Neurodegenerative diseases: lessons from genome‐wide screens in small model organisms
TJ Van Ham, R Breitling, MA Swertz, EAA Nollen
EMBO molecular medicine 1 (8‐9), 360-370, 2009
1072009
A small molecule that induces intrinsic pathway apoptosis with unparalleled speed
R Palchaudhuri, MJ Lambrecht, RC Botham, KC Partlow, TJ Van Ham, ...
Cell reports 13 (9), 2027-2036, 2015
972015
Towards multiparametric fluorescent imaging of amyloid formation: studies of a YFP model of α-synuclein aggregation
TJ van Ham, A Esposito, JR Kumita, STD Hsu, GSK Schierle, CF Kaminski, ...
Journal of molecular biology 395 (3), 627-642, 2010
912010
Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes
H Gui, D Schriemer, WW Cheng, RK Chauhan, G Antiňolo, C Berrios, ...
Genome biology 18, 1-13, 2017
892017
Identification of a conserved and acute neurodegeneration‐specific microglial transcriptome in the zebrafish
N Oosterhof, IR Holtman, LE Kuil, HC van der Linde, EWGM Boddeke, ...
Glia 65 (1), 138-149, 2017
892017
Apoptotic cells are cleared by directional migration and elmo1-dependent macrophage engulfment
TJ van Ham, D Kokel, RT Peterson
Current Biology 22 (9), 830-836, 2012
862012
Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation
TJ van Ham, CA Brady, RD Kalicharan, N Oosterhof, J Kuipers, ...
Disease models & mechanisms 7 (7), 857-869, 2014
672014
Gene expression profiling reveals a conserved microglia signature in larval zebrafish
J Mazzolini, S Le Clerc, G Morisse, C Coulonges, LE Kuil, TJ Van Ham, ...
Glia 68 (2), 298-315, 2020
642020
Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases
E Perenthaler, A Nikoncuk, S Yousefi, WM Berdowski, M Alsagob, I Capo, ...
Acta neuropathologica 139, 415-442, 2020
622020
Immune cell dynamics in the CNS: Learning from the zebrafish
N Oosterhof, E Boddeke, TJ van Ham
Glia 63 (5), 719-735, 2015
572015
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