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Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications F Nazio, M Bordi, V Cianfanelli, F Locatelli, F Cecconi Cell Death & Differentiation 26 (4), 690-702, 2019 | 372 | 2019 |
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy M Bordi, MJ Berg, PS Mohan, CM Peterhoff, MJ Alldred, S Che, ... Autophagy 12 (12), 2467-2483, 2016 | 338 | 2016 |
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S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy S Rizza, S Cardaci, C Montagna, G Di Giacomo, D De Zio, M Bordi, ... Proceedings of the National Academy of Sciences 115 (15), E3388-E3397, 2018 | 178 | 2018 |
Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-βCTF (C99) Y Jiang, Y Sato, E Im, M Berg, M Bordi, S Darji, A Kumar, PS Mohan, ... Journal of Neuroscience 39 (27), 5255-5268, 2019 | 130 | 2019 |
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity E Maiani, G Milletti, F Nazio, SG Holdgaard, J Bartkova, S Rizza, ... Nature 592 (7856), 799-803, 2021 | 109 | 2021 |
Drp1 controls effective T cell immune-surveillance by regulating T cell migration, proliferation, and cMyc-dependent metabolic reprogramming L Simula, I Pacella, A Colamatteo, C Procaccini, V Cancila, M Bordi, ... Cell reports 25 (11), 3059-3073. e10, 2018 | 109 | 2018 |
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The crystal structure of the Drosophila germline inducer Oskar identifies two domains with distinct Vasa helicase-and RNA-binding activities M Jeske, M Bordi, S Glatt, S Müller, V Rybin, CW Müller, A Ephrussi Cell reports 12 (4), 587-598, 2015 | 93 | 2015 |
mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy M Bordi, S Darji, Y Sato, M Mellén, MJ Berg, A Kumar, Y Jiang, RA Nixon Cell Death & Disease 10 (8), 563, 2019 | 92 | 2019 |
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The close interconnection between mitochondrial dynamics and mitophagy in cancer M Bordi, F Nazio, S Campello Frontiers in oncology 7, 81, 2017 | 76 | 2017 |
Controlled cycling and quiescence enables efficient HDR in engraftment-enriched adult hematopoietic stem and progenitor cells JJ Shin, MS Schröder, F Caiado, SK Wyman, NL Bray, M Bordi, MA Dewitt, ... Cell reports 32 (9), 2020 | 73 | 2020 |
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Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling F Nazio, A Po, L Abballe, C Ballabio, F Diomedi Camassei, M Bordi, ... Acta neuropathologica 142, 537-564, 2021 | 33 | 2021 |
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