David CS Huang

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Andreas StrasserThe Walter and Eliza Hall InstituteEmail yang diverifikasi di wehi.edu.au
Andrew W RobertsWalter and Eliza Hall Institute of Medical Research; Royal Melbourne HospitalEmail yang diverifikasi di wehi.edu.au
Peter CzabotarThe Walter & Eliza Hall Institute of Medical ResearchEmail yang diverifikasi di wehi.edu.au
Andrew H. WeiPeter MacCallum Cancer Centre, Royal Melbourne Hospital and Walter and Eliza Hall Institute ofEmail yang diverifikasi di petermac.org
Hamsa PuthalakathAssociate ProfessorEmail yang diverifikasi di latrobe.edu.au
peter m colmanEmail yang diverifikasi di wehi.edu.au
Guillaume LesseneThe Walter and Eliza Hall Institute of Medical ResearchEmail yang diverifikasi di wehi.edu.au
Douglas FairlieOlivia Newton-John Cancer Research Institute and La Trobe UniversityEmail yang diverifikasi di onjcri.org.au
John F SeymourProfessor of Medicine, Director Dept of Haematology Peter MacCallum Cancer Centre & Royal MelbourneEmail yang diverifikasi di petermac.org
Kylie D MasonWalter and Eliza HallEmail yang diverifikasi di wehi.edu.au
Erinna LeeLaboratory Head, La Trobe UniversityEmail yang diverifikasi di latrobe.edu.au
Jianan GongWalter and Eliza Hall Institute of Medical ResearchEmail yang diverifikasi di wehi.edu.au
Em. Prof. Brian J SmithLa Trobe Institute for Molecular ScienceEmail yang diverifikasi di latrobe.edu.au
Mark HindsEmail yang diverifikasi di unimelb.edu.au
Catherine L DayNew ZealandEmail yang diverifikasi di otago.ac.nz
Marco HeroldOlivia Newton-John Cancer Research InstituteEmail yang diverifikasi di onjcri.org.au
Benjamin T. KileGarvan Institute of Medical ResearchEmail yang diverifikasi di garvan.org.au
Seong Lin KhawEmail yang diverifikasi di rch.org.au
Daniel GrayThe Walter and Eliza Hall InstituteEmail yang diverifikasi di wehi.edu.au
David TarlintonMonash UniversityEmail yang diverifikasi di monash.edu

Ikuti

David CS Huang

The Walter and Eliza Hall Institute of Medical Research

Email yang diverifikasi di wehi.edu.au

BCL2 venetoclax leukemia lymphoma


Judul Urutkan menurut kutipan Urutkan menurut tahun Urutkan menurut judul	Dikutip oleh Dikutip oleh	Tahun
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets AJ Souers, JD Leverson, ER Boghaert, SL Ackler, ND Catron, J Chen, ... Nature medicine 19 (2), 202-208, 2013	3309	2013
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function L Chen, SN Willis, A Wei, BJ Smith, JI Fletcher, MG Hinds, PM Colman, ... Molecular cell 17 (3), 393-403, 2005	2304	2005
The Bcl-2 family: roles in cell survival and oncogenesis S Cory, D Huang, JM Adams Oncogene 22 (53), 8590-8607, 2003	2132	2003
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity P Bouillet, D Metcalf, DCS Huang, DM Tarlinton, TWH Kay, F Kontgen, ... Science 286 (5445), 1735-1738, 1999	1917	1999
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins SN Willis, L Chen, G Dewson, A Wei, E Naik, JI Fletcher, JM Adams, ... Genes & development 19 (11), 1294-1305, 2005	1629	2005
Bim: a novel member of the Bcl‐2 family that promotes apoptosis L O'Connor, A Strasser, LA O'Reilly, G Hausmann, JM Adams, S Cory, ... The EMBO journal, 1998	1498	1998
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized MF Van Delft, AH Wei, KD Mason, CJ Vandenberg, L Chen, PE Czabotar, ... Cancer cell 10 (5), 389-399, 2006	1490	2006
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex H Puthalakath, DCS Huang, LA O’Reilly, SM King, A Strasser Molecular cell 3 (3), 287-296, 1999	1487	1999
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak SN Willis, JI Fletcher, T Kaufmann, MF van Delft, L Chen, PE Czabotar, ... Science 315 (5813), 856-859, 2007	1478	2007
BH3-only proteins—essential initiators of apoptotic cell death DCS Huang, A Strasser Cell 103 (6), 839-842, 2000	1425	2000
Programmed anuclear cell death delimits platelet life span KD Mason, MR Carpinelli, JI Fletcher, JE Collinge, AA Hilton, S Ellis, ... Cell 128 (6), 1173-1186, 2007	1252	2007
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models A Kotschy, Z Szlavik, J Murray, J Davidson, AL Maragno, ... Nature 538 (7626), 477-482, 2016	1099	2016
Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease AW Roberts, JF Seymour, JR Brown, WG Wierda, TJ Kipps, SL Khaw, ... Journal of Clinical Oncology 30 (5), 488-496, 2012	978	2012
Bcl‐2 and Fas/APO‐1 regulate distinct pathways to lymphocyte apoptosis. A Strasser, AW Harris, DC Huang, PH Krammer, S Cory The EMBO journal 14 (24), 6136-6147, 1995	939	1995
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production MJ White, K McArthur, D Metcalf, RM Lane, JC Cambier, MJ Herold, ... Cell 159 (7), 1549-1562, 2014	921	2014
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7 IE Wertz, S Kusam, C Lam, T Okamoto, W Sandoval, DJ Anderson, ... Nature 471 (7336), 110-114, 2011	916	2011
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis H Puthalakath, A Villunger, LA O'Reilly, JG Beaumont, L Coultas, ... Science 293 (5536), 1829-1832, 2001	838	2001
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival M Schwickart, XD Huang, JR Lill, J Liu, R Ferrando, DM French, ... Nature 463 (7277), 103-107, 2010	754	2010
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome VS Marsden, L O'Connor, LA O'Reilly, J Silke, D Metcalf, PG Ekert, ... Nature 419 (6907), 634-637, 2002	730	2002
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ... Cell 152 (3), 519-531, 2013	671	2013

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