Macrophage activation and polarization: nomenclature and experimental guidelines PJ Murray, JE Allen, SK Biswas, EA Fisher, DW Gilroy, S Goerdt, ... Immunity 41 (1), 14-20, 2014 | 6389 | 2014 |
A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes SM Sidik, D Huet, SM Ganesan, MH Huynh, T Wang, AS Nasamu, P Thiru, ... Cell 166 (6), 1423-1435. e12, 2016 | 825 | 2016 |
Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue JPJ Saeij, S Coller, JP Boyle, ME Jerome, MW White, JC Boothroyd Nature 445 (7125), 324-327, 2007 | 689 | 2007 |
Polymorphic secreted kinases are key virulence factors in toxoplasmosis JPJ Saeij, JP Boyle, S Coller, S Taylor, LD Sibley, ET Brooke-Powell, ... Science 314 (5806), 1780-1783, 2006 | 685 | 2006 |
Strain-specific activation of the NF-κB pathway by GRA15, a novel Toxoplasma gondii dense granule protein EE Rosowski, D Lu, L Julien, L Rodda, RA Gaiser, KDC Jensen, JPJ Saeij Journal of Experimental Medicine 208 (1), 195-212, 2011 | 482 | 2011 |
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host JPJ Saeij, JP Boyle, JC Boothroyd Trends in parasitology 21 (10), 476-481, 2005 | 426 | 2005 |
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence ML Reese, GM Zeiner, JPJ Saeij, JC Boothroyd, JP Boyle Proceedings of the National Academy of Sciences 108 (23), 9625-9630, 2011 | 296 | 2011 |
Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence IJ Blader, JP Saeij Apmis 117 (5‐6), 458-476, 2009 | 291 | 2009 |
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes H Lorenzi, A Khan, MS Behnke, S Namasivayam, LS Swapna, ... Nature communications 7 (1), 10147, 2016 | 283 | 2016 |
The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole DA Gold, AD Kaplan, A Lis, GCL Bett, EE Rosowski, KM Cirelli, ... Cell host & microbe 17 (5), 642-652, 2015 | 260 | 2015 |
Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation KDC Jensen, Y Wang, EDT Wojno, AJ Shastri, K Hu, L Cornel, E Boedec, ... Cell host & microbe 9 (6), 472-483, 2011 | 259 | 2011 |
Bioluminescence Imaging of Toxoplasma gondii Infection in Living Mice Reveals Dramatic Differences between Strains JPJ Saeij, JP Boyle, ME Grigg, G Arrizabalaga, JC Boothroyd Infection and immunity 73 (2), 695-702, 2005 | 259 | 2005 |
The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response W Niedelman, DA Gold, EE Rosowski, JK Sprokholt, D Lim, ... PLoS pathogens 8 (6), e1002784, 2012 | 251 | 2012 |
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii G Gorfu, KM Cirelli, MB Melo, K Mayer-Barber, D Crown, BH Koller, ... MBio 5 (1), 10.1128/mbio. 01117-13, 2014 | 245 | 2014 |
Toxoplasma gondii effectors are master regulators of the inflammatory response MB Melo, KDC Jensen, JPJ Saeij Trends in parasitology 27 (11), 487-495, 2011 | 243 | 2011 |
Identification of a master regulator of differentiation in Toxoplasma BS Waldman, D Schwarz, MH Wadsworth, JP Saeij, AK Shalek, S Lourido Cell 180 (2), 359-372. e16, 2020 | 223 | 2020 |
Molecular and functional characterization of carp TNF: a link between TNF polymorphism and trypanotolerance? JPJ Saeij, RJM Stet, BJ de Vries, WB van Muiswinkel, GF Wiegertjes Developmental & Comparative Immunology 27 (1), 29-41, 2003 | 185 | 2003 |
Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii KM Cirelli, G Gorfu, MA Hassan, M Printz, D Crown, SH Leppla, ME Grigg, ... PLoS pathogens 10 (3), e1003927, 2014 | 168 | 2014 |
Molecular and functional characterization of a fish inducible-type nitric oxide synthase JPJ Saeij, RJM Stet, A Groeneveld, LBM Verburg-van Kemenade, ... Immunogenetics 51, 339-346, 2000 | 166 | 2000 |
Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It S Virreira Winter, W Niedelman, KD Jensen, EE Rosowski, L Julien, ... PloS one 6 (9), e24434, 2011 | 159 | 2011 |