Practical synthesis of oligosaccharides. Partial synthesis of avermectin B1a KC Nicolaou, RE Dolle, DP Papahatjis Journal of the American Chemical Society 106 (15), 4189-4192, 1984 | 426 | 1984 |
A mild and general method for the synthesis of 0-glycosides KC Nicolaou, SP Seitz, DP Papahatjis Journal of the American Chemical Society 105 (8), 2430-2434, 1983 | 405 | 1983 |
Novel Analogues of Arachidonylethanolamide (Anandamide): Affinities for the CB1 and CB2 Cannabinoid Receptors and Metabolic Stability AM Sonyuan Lin, Atmaram D. Khanolkar, Pusheng Fan, Andreas Goutopoulos, Ce ... Journal of Medicinal Chemistry 41 (27), 5353-5361, 1998 | 204 | 1998 |
Total synthesis of amphoteronolide B and amphotericin B. 1. Strategy and stereocontrolled construction of key building blocks KC Nicolaou, RA Daines, J Uenishi, WS Li, DP Papahatjis, ... Journal of the American Chemical Society 110 (14), 4672-4685, 1988 | 175 | 1988 |
Total synthesis of ionophore antibiotic X-14547A KC Nicolaou, DP Papahatjis, DA Claremon, RL Magolda, RE Dolle The Journal of Organic Chemistry 50 (9), 1440-1456, 1985 | 161 | 1985 |
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity AD Khanolkar, D Lu, M Ibrahim, RI Duclos, Jr, GA Thakur, TP Malan, Jr, ... Journal of medicinal chemistry 50 (26), 6493-6500, 2007 | 115 | 2007 |
A mild method for the synthesis of 2-ketopyrroles from carboxylic acids KC Nicolaou, DA Claremon, DP Papahatjis Tetrahedron Letters 22 (46), 4647-4650, 1981 | 103 | 1981 |
Pharmacophoric Requirements for Cannabinoid Side Chains: Multiple Bond and C1‘-Substituted Δ8-Tetrahydrocannabinols DP Papahatjis, T Kourouli, V Abadji, A Goutopoulos, A Makriyannis Journal of medicinal chemistry 41 (7), 1195-1200, 1998 | 86 | 1998 |
Total synthesis of ionophore antibiotic X-14547A. 1. Enantioselective synthesis of the tetrahydropyran and tetrahydroindan building blocks KC Nicolaou, DP Papahatjis, DA Claremon, RE Dolle III Journal of the American Chemical Society 103 (23), 6967-6969, 1981 | 81 | 1981 |
The cannabinoid CB1 receptor biphasically modulates motor activity and regulates dopamine and glutamate release region dependently A Polissidis, A Galanopoulos, G Naxakis, D Papahatjis, ... International Journal of Neuropsychopharmacology 16 (2), 393-403, 2013 | 78 | 2013 |
Novel 1′, 1′-chain substituted hexahydrocannabinols: 9β-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist SP Nikas, SO Alapafuja, I Papanastasiou, CA Paronis, VG Shukla, ... Journal of medicinal chemistry 53 (19), 6996-7010, 2010 | 73 | 2010 |
Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1 ‘ DP Papahatjis, SP Nikas, T Kourouli, R Chari, W Xu, RG Pertwee, ... Journal of medicinal chemistry 46 (15), 3221-3229, 2003 | 70 | 2003 |
Novel 1′, 1′-chain substituted Δ8-tetrahydrocannabinols DP Papahatjis, SP Nikas, T Andreou, A Makriyannis Bioorganic & medicinal chemistry letters 12 (24), 3583-3586, 2002 | 70 | 2002 |
The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the c1 ‘position of the alkyl side chain on the structural requirements for binding to … S Durdagi, A Kapou, T Kourouli, T Andreou, SP Nikas, VR Nahmias, ... Journal of medicinal chemistry 50 (12), 2875-2885, 2007 | 60 | 2007 |
C1 ‘-cycloalkyl side chain pharmacophore in tetrahydrocannabinols DP Papahatjis, VR Nahmias, SP Nikas, T Andreou, SO Alapafuja, ... Journal of medicinal chemistry 50 (17), 4048-4060, 2007 | 57 | 2007 |
Studies on the thermotropic effects of cannabinoids on phosphatidylcholine bilayers using differential scanning calorimetry and small angle X-ray diffraction T Mavromoustakos, E Theodoropoulou, D Papahatjis, T Kourouli, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1281 (2), 235-244, 1996 | 56 | 1996 |
Mapping the Melatonin Receptor. 7. Subtype Selective Ligands Based on β-Substituted N-Acyl-5-methoxytryptamines and β-Substituted N-Acyl-5-methoxy-1 … A Tsotinis, M Vlachou, DP Papahatjis, T Calogeropoulou, SP Nikas, ... Journal of medicinal chemistry 49 (12), 3509-3519, 2006 | 54 | 2006 |
Total synthesis of ionophore antibiotic X-14547A. 2. Coupling of the tetrahydropyran and tetrahydroindan systems and construction of the butadienyl and ketopyrrole moieties KC Nicolaou, DA Claremon, DP Papahatjis, RL Magolda Journal of the American Chemical Society 103 (23), 6969-6971, 1981 | 50 | 1981 |
The role of halogen substitution in classical cannabinoids: a CB1 pharmacophore model SP Nikas, J Grzybowska, DP Papahatjis, A Charalambous, AR Banijamali, ... The AAPS journal 6, 23-35, 2004 | 47 | 2004 |
Stereocontrolled construction of key building blocks for the total synthesis of amphoteronolide B and amphotericin B KC Nicolaou, RA Daines, J Uenishi, WS Li, DP Papahatjis, ... Journal of the American Chemical Society 109 (7), 2205-2208, 1987 | 45 | 1987 |