Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury RC Lai, F Arslan, MM Lee, NSK Sze, A Choo, TS Chen, M Salto-Tellez, ... Stem cell research 4 (3), 214-222, 2010 | 2512 | 2010 |
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse … F Arslan, RC Lai, MB Smeets, L Akeroyd, A Choo, ENE Aguor, L Timmers, ... Stem cell research 10 (3), 301-312, 2013 | 1258 | 2013 |
Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium L Timmers, SK Lim, F Arslan, JS Armstrong, IE Hoefer, PA Doevendans, ... Stem cell research 1 (2), 129-137, 2008 | 787 | 2008 |
Prognostic value of fractional flow reserve: linking physiologic severity to clinical outcomes NP Johnson, GG Tóth, D Lai, H Zhu, G Açar, P Agostoni, Y Appelman, ... Journal of the American College of Cardiology 64 (16), 1641-1654, 2014 | 698 | 2014 |
Proteolytic potential of the MSC exosome proteome: Implications for an exosome‐mediated delivery of therapeutic proteasome RC Lai, SS Tan, BJ Teh, SK Sze, F Arslan, DP De Kleijn, A Choo, SK Lim International journal of proteomics 2012 (1), 971907, 2012 | 533 | 2012 |
Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction L Timmers, SK Lim, IE Hoefer, F Arslan, RC Lai, AAM van Oorschot, ... Stem cell research 6 (3), 206-214, 2011 | 515 | 2011 |
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti–toll-like receptor-2 antibody F Arslan, MB Smeets, LAJ O'Neill, B Keogh, P McGuirk, L Timmers, ... Circulation 121 (1), 80-90, 2010 | 463 | 2010 |
Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs TS Chen, F Arslan, Y Yin, SS Tan, RC Lai, ABH Choo, J Padmanabhan, ... Journal of translational medicine 9, 1-10, 2011 | 434 | 2011 |
Innate immune signaling in cardiac ischemia F Arslan, DP De Kleijn, G Pasterkamp Nature Reviews Cardiology 8 (5), 292-300, 2011 | 424 | 2011 |
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia–reperfusion in vivo MIFJ Oerlemans, J Liu, F Arslan, K den Ouden, BJ van Middelaar, ... Basic research in cardiology 107, 1-13, 2012 | 393 | 2012 |
The innate immune response in reperfused myocardium L Timmers, G Pasterkamp, VC de Hoog, F Arslan, Y Appelman, ... Cardiovascular research 94 (2), 276-283, 2012 | 371 | 2012 |
The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction GPJ Van Hout, L Bosch, GHJM Ellenbroek, JJ De Haan, WW Van Solinge, ... European heart journal 38 (11), 828-836, 2017 | 350 | 2017 |
Right ventricular dysfunction in left‐sided heart failure with preserved versus reduced ejection fraction L Bosch, CSP Lam, L Gong, SP Chan, D Sim, D Yeo, F Jaufeerally, ... European journal of heart failure 19 (12), 1664-1671, 2017 | 343 | 2017 |
TLR2 and TLR4 in ischemia reperfusion injury F Arslan, B Keogh, P McGuirk, AE Parker Mediators of inflammation 2010 (1), 704202, 2010 | 229 | 2010 |
Lack of fibronectin-EDA promotes survival and prevents adverse remodeling and heart function deterioration after myocardial infarction F Arslan, MB Smeets, PW Riem Vis, JC Karper, PH Quax, LG Bongartz, ... Circulation research 108 (5), 582-592, 2011 | 196 | 2011 |
Danger signals in the initiation of the inflammatory response after myocardial infarction JJ De Haan, MB Smeets, G Pasterkamp, F Arslan Mediators of inflammation 2013 (1), 206039, 2013 | 182 | 2013 |
Derivation and characterization of human fetal MSCs: an alternative cell source for large-scale production of cardioprotective microparticles RC Lai, F Arslan, SS Tan, B Tan, A Choo, MM Lee, TS Chen, BJ Teh, ... Journal of molecular and cellular cardiology 48 (6), 1215-1224, 2010 | 178 | 2010 |
Treatment with OPN-305, a humanized anti–Toll-like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs F Arslan, JH Houtgraaf, B Keogh, K Kazemi, R de Jong, WJ McCormack, ... Circulation: Cardiovascular Interventions 5 (2), 279-287, 2012 | 137 | 2012 |
Intracoronary infusion of allogeneic mesenchymal precursor cells directly after experimental acute myocardial infarction reduces infarct size, abrogates adverse remodeling, and … JH Houtgraaf, R De Jong, K Kazemi, D De Groot, TIG Van Der Spoel, ... Circulation research 113 (2), 153-166, 2013 | 130 | 2013 |
Endogenous inflammatory molecules engage Toll-like receptors in cardiovascular disease MG Ionita, F Arslan, DPV De Kleijn, G Pasterkamp Journal of innate immunity 2 (4), 307-315, 2010 | 112 | 2010 |