| Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab HS Cho, K Mason, KX Ramyar, AM Stanley, SB Gabelli, DW Denney Jr, ... Nature 421 (6924), 756-760, 2003 | 2069 | 2003 |
| Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex MC Franklin, KD Carey, FF Vajdos, DJ Leahy, AM De Vos, MX Sliwkowski Cancer cell 5 (4), 317-328, 2004 | 1461 | 2004 |
| An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors AW Burgess, HS Cho, C Eigenbrot, KM Ferguson, TPJ Garrett, DJ Leahy, ... Molecular cell 12 (3), 541-552, 2003 | 1336 | 2003 |
| EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization KM Ferguson, MB Berger, JM Mendrola, HS Cho, DJ Leahy, MA Lemmon Molecular cell 11 (2), 507-517, 2003 | 1050 | 2003 |
| 2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region DJ Leahy, I Aukhil, HP Erickson Cell 84 (1), 155-164, 1996 | 917 | 1996 |
| Functionally significant insulin-like growth factor I receptor mutations in centenarians Y Suh, G Atzmon, MO Cho, D Hwang, B Liu, DJ Leahy, N Barzilai, ... Proceedings of the National Academy of Sciences 105 (9), 3438-3442, 2008 | 898 | 2008 |
| Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein DJ Leahy, WA Hendrickson, lkramuddin Aukhil, HP Erickson Science 258 (5084), 987-991, 1992 | 724 | 1992 |
| Transient mammalian cell transfection with polyethylenimine (PEI) PA Longo, JM Kavran, MS Kim, DJ Leahy Methods in enzymology 529, 227-240, 2013 | 684 | 2013 |
| Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains CE Dann, JC Hsieh, A Rattner, D Sharma, J Nathans, DJ Leahy Nature 412 (6842), 86-90, 2001 | 651 | 2001 |
| Structure of the extracellular region of HER3 reveals an interdomain tether HS Cho, DJ Leahy Science 297 (5585), 1330-1333, 2002 | 606 | 2002 |
| Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain JC Lee, I Vivanco, R Beroukhim, JHY Huang, WL Feng, RM DeBiasi, ... PLoS medicine 3 (12), e485, 2006 | 439 | 2006 |
| Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin. A Qu, DJ Leahy Proceedings of the National Academy of Sciences 92 (22), 10277-10281, 1995 | 425 | 1995 |
| EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics DM Freed, NJ Bessman, A Kiyatkin, E Salazar-Cavazos, PO Byrne, ... Cell 171 (3), 683-695. e18, 2017 | 373 | 2017 |
| Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution DJ Leahy, R Axel, WA Hendrickson Cell 68 (6), 1145-1162, 1992 | 367 | 1992 |
| Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins TMT Hall, JA Porter, KE Young, EV Koonin, PA Beachy, DJ Leahy Cell 91 (1), 85-97, 1997 | 334 | 1997 |
| Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm DHC Doyle AJ1, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D ... Nature Genetics 44 (11), 1249-54, 2012 | 313 | 2012 |
| Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor BP Barnett, Y Hwang, MS Taylor, H Kirchner, PT Pfluger, V Bernard, Y Lin, ... Science 330 (6011), 1689-1692, 2010 | 303 | 2010 |
| Interactions between Hedgehog proteins and their binding partners come into view PA Beachy, SG Hymowitz, RA Lazarus, DJ Leahy, C Siebold Genes & development 24 (18), 2001-2012, 2010 | 273 | 2010 |
| Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165 C Gu, BJ Limberg, GB Whitaker, B Perman, DJ Leahy, JS Rosenbaum, ... Journal of Biological Chemistry 277 (20), 18069-18076, 2002 | 272 | 2002 |
| Structural basis for ligand and heparin binding to neuropilin B domains CW Vander Kooi, MA Jusino, B Perman, DB Neau, HD Bellamy, DJ Leahy Proceedings of the National Academy of Sciences 104 (15), 6152-6157, 2007 | 271 | 2007 |
