| The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes AM Pickering, AL Koop, CY Teoh, G Ermak, T Grune, KJA Davies Biochemical Journal 432 (3), 585-595, 2010 | 381 | 2010 |
| Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress AM Pickering, RA Linder, H Zhang, HJ Forman, KJA Davies Journal of Biological Chemistry 287 (13), 10021-10031, 2012 | 322 | 2012 |
| HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress T Grune, B Catalgol, A Licht, G Ermak, AM Pickering, JK Ngo, KJA Davies Free Radical Biology and Medicine 51 (7), 1355-1364, 2011 | 239 | 2011 |
| Degradation of damaged proteins: the main function of the 20S proteasome AM Pickering, KJA Davies Progress in molecular biology and translational science 109, 227-248, 2012 | 222 | 2012 |
| Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins AM Pickering, KJA Davies Archives of biochemistry and biophysics 523 (2), 181-190, 2012 | 167 | 2012 |
| Oxidative stress adaptation with acute, chronic, and repeated stress AM Pickering, L Vojtovich, J Tower, KJA Davies Free Radical Biology and Medicine 55, 109-118, 2013 | 160 | 2013 |
| Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours Z Zhu, A Achreja, N Meurs, O Animasahun, S Owen, A Mittal, P Parikh, ... Nature Metabolism 2 (8), 775-792, 2020 | 154 | 2020 |
| Cause or casualty: The role of mitochondrial DNA in aging and age-associated disease ES Chocron, E Munkácsy, AM Pickering Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (2), 285-297, 2019 | 111 | 2019 |
| A conserved role for the 20S proteasome and Nrf2 transcription factor in oxidative stress adaptation in mammals, Caenorhabditis elegans and Drosophila melanogaster AM Pickering, TA Staab, J Tower, D Sieburth, KJA Davies Journal of Experimental Biology 216 (4), 543-553, 2013 | 110 | 2013 |
| Lifespan of mice and primates correlates with immunoproteasome expression AM Pickering, M Lehr, RA Miller The Journal of clinical investigation 125 (5), 2059-2068, 2015 | 83 | 2015 |
| Proline-and arginine-rich peptides as flexible allosteric modulators of human proteasome activity M Giżyńska, J Witkowska, P Karpowicz, R Rostankowski, ES Chocron, ... Journal of Medicinal Chemistry 62 (1), 359-370, 2018 | 48 | 2018 |
| Fibroblasts from longer-lived species of primates, rodents, bats, carnivores, and birds resist protein damage AM Pickering, M Lehr, WJ Kohler, ML Han, RA Miller Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2015 | 48 | 2015 |
| Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models ES Chocron, E Munkácsy, HS Kim, P Karpowicz, N Jiang, CE Van Skike, ... Science advances 8 (23), eabk2252, 2022 | 42 | 2022 |
| A simple fluorescence labeling method for studies of protein oxidation, protein modification, and proteolysis AM Pickering, KJA Davies Free Radical Biology and Medicine 52 (2), 239-246, 2012 | 37 | 2012 |
| The proteasome: A key modulator of nervous system function, brain aging, and neurodegenerative disease K Davidson, AM Pickering Frontiers in Cell and Developmental Biology 11, 1124907, 2023 | 36 | 2023 |
| Neuronal‐specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age‐related cognitive decline E Munkácsy, ES Chocron, L Quintanilla, CM Gendron, SD Pletcher, ... Aging cell 18 (5), e13005, 2019 | 35 | 2019 |
| Gut-and oral-dysbiosis differentially impact spinal-and bulbar-onset ALS, predicting ALS severity and potentially determining the location of disease onset HS Kim, J Son, D Lee, J Tsai, D Wang, ES Chocron, S Jeong, P Kittrell, ... BMC neurology 22 (1), 62, 2022 | 32 | 2022 |
| Mitochondrial thioredoxin reductase 2 is elevated in long‐lived primate as well as rodent species and extends fly mean lifespan AM Pickering, M Lehr, CM Gendron, SD Pletcher, RA Miller Aging Cell 16 (4), 683-692, 2017 | 30 | 2017 |
| New peptide-based pharmacophore activates 20S proteasome PA Osmulski, P Karpowicz, E Jankowska, J Bohmann, AM Pickering, ... Molecules 25 (6), 1439, 2020 | 27 | 2020 |
| Protein translation paradox: Implications in translational regulation of aging HS Kim, AM Pickering Frontiers in Cell and Developmental Biology 11, 1129281, 2023 | 25 | 2023 |