The ABC protein turned chloride channel whose failure causes cystic fibrosis DC Gadsby, P Vergani, L Csanády Nature 440 (7083), 477-483, 2006 | 940 | 2006 |
Molecular structure of the human CFTR ion channel F Liu, Z Zhang, L Csanády, DC Gadsby, J Chen Cell 169 (1), 85-95. e8, 2017 | 590 | 2017 |
Structure, gating, and regulation of the CFTR anion channel L Csanády, P Vergani, DC Gadsby Physiological reviews 99 (1), 707-738, 2019 | 250 | 2019 |
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation Z Zhang, B Toth, A Szollosi, J Chen, L Csanady elife 7, e36409, 2018 | 149 | 2018 |
Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains L Csanády, KW Chan, D Seto-Young, DC Kopsco, AC Nairn, DC Gadsby The Journal of general physiology 116 (3), 477-500, 2000 | 147 | 2000 |
Strict coupling between CFTR’s catalytic cycle and gating of its Cl− ion pore revealed by distributions of open channel burst durations L Csanády, P Vergani, DC Gadsby Proceedings of the National Academy of Sciences 107 (3), 1241-1246, 2010 | 140 | 2010 |
A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT C Chinopoulos, S Vajda, L Csanády, M Mándi, K Mathe, V Adam-Vizi Biophysical journal 96 (6), 2490-2504, 2009 | 130 | 2009 |
Four Ca2+ Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate L Csanády, B Törőcsik Journal of General Physiology 133 (2), 189-203, 2009 | 123 | 2009 |
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel B Tóth, L Csanády Journal of Biological Chemistry 285 (39), 30091-30102, 2010 | 120 | 2010 |
Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA L Csanády, D Seto-Young, KW Chan, C Cenciarelli, BB Angel, J Qin, ... Journal of General Physiology 125 (2), 171-186, 2005 | 92 | 2005 |
Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding Domain KW Chan, L Csanády, D Seto-Young, AC Nairn, DC Gadsby The Journal of general physiology 116 (2), 163-180, 2000 | 92 | 2000 |
Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents B Tóth, L Csanády Proceedings of the National Academy of Sciences 109 (33), 13440-13445, 2012 | 80 | 2012 |
Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms L Csanády Biophysical Journal 78 (2), 785-799, 2000 | 77 | 2000 |
Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2′-phosphate B Tóth, I Iordanov, L Csanády Journal of General Physiology 145 (5), 419-430, 2015 | 73 | 2015 |
Functional Roles of Nonconserved Structural Segments in CFTR's NH2-terminal Nucleotide Binding Domain L Csanády, KW Chan, AC Nairn, DC Gadsby The Journal of general physiology 125 (1), 43-55, 2005 | 68 | 2005 |
Timing of CFTR pore opening and structure of its transition state B Sorum, D Czégé, L Csanády Cell 163 (3), 724-733, 2015 | 67 | 2015 |
Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle L Csanády, AC Nairn, DC Gadsby Journal of General Physiology 128 (5), 523-533, 2006 | 66 | 2006 |
A single active catalytic site is sufficient to promote transport in P-glycoprotein O Bársony, G Szalóki, D Türk, S Tarapcsák, Z Gutay-Tóth, Z Bacsó, ... Scientific reports 6 (1), 24810, 2016 | 61 | 2016 |
The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity I Iordanov, C Mihalyi, B Toth, L Csanady Elife 5, e17600, 2016 | 55 | 2016 |
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating B Tóth, I Iordanov, L Csanády Proceedings of the National Academy of Sciences 111 (47), 16949-16954, 2014 | 51 | 2014 |