| Molecular docking characterizes substrate-binding sites and efflux modulation mechanisms within P-glycoprotein. RJ Ferreira, MJU Ferreira, DJVA Dos Santos Journal of chemical information and modeling 53 (7), 1747-1760, 2013 | 186 | 2013 |
| Insights on P-glycoprotein’s efflux mechanism obtained by molecular dynamics simulations RJ Ferreira, MJU Ferreira, DJVA Dos Santos Journal of Chemical Theory and Computation 8 (6), 1853-1864, 2012 | 146 | 2012 |
| Inhibition of multidrug resistance of cancer cells by natural diterpenes, triterpenes and carotenoids J Molnár, N Gyémánt, M Tanaka, J Hohmann, E Bergmann-Leitner, ... Current pharmaceutical design 12 (3), 287-311, 2006 | 145 | 2006 |
| Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique X Luo, D Pires, JA Aínsa, B Gracia, S Mulhovo, A Duarte, E Anes, ... Journal of Ethnopharmacology 137 (1), 114-120, 2011 | 116 | 2011 |
| Evaluation of the Antiviral and Antimicrobial Activities of Triterpenes Isolated from Euphorbia segetalis AM Madureira, JR Ascenso, L Valdeira, A Duarte, JP Frade, G Freitas, ... Natural Product Research 17 (5), 375-380, 2003 | 114 | 2003 |
| Antitumor activity of terpenoids against classical and atypical multidrug resistant cancer cells H Lage, N Duarte, C Coburger, A Hilgeroth, MJU Ferreira Phytomedicine 17 (6), 441-448, 2010 | 111 | 2010 |
| Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids N Duarte, A Varga, G Cherepnev, R Radics, J Molnár, MJU Ferreira Bioorganic & Medicinal Chemistry 15 (1), 546-554, 2007 | 111 | 2007 |
| Bioactive Diterpenoids, a New Jatrophane and Two ent-Abietanes, and Other Constituents from Euphorbia pubescens C Valente, M Pedro, A Duarte, MSJ Nascimento, PM Abreu, MJU Ferreira Journal of Natural Products 67 (5), 902-904, 2004 | 96 | 2004 |
| P-glycoprotein and membrane roles in multidrug resistance RJ Ferreira, DJ Dos Santos, MJU Ferreira Future medicinal chemistry 7 (7), 929-946, 2015 | 93 | 2015 |
| New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells N Duarte, N Gyémánt, PM Abreu, J Molnár, MJU Ferreira Planta medica 72 (02), 162-168, 2006 | 87 | 2006 |
| Antibacterial activity of some African medicinal plants used traditionally against infectious diseases AM Madureira, C Ramalhete, S Mulhovo, A Duarte, MJU Ferreira Pharmaceutical Biology 50 (4), 481-489, 2012 | 86 | 2012 |
| Isoflavones as apoptosis inducers in human hepatoma HuH‐7 cells TA Mansoor, RM Ramalho, X Luo, C Ramalhete, CMP Rodrigues, ... Phytotherapy Research 25 (12), 1819-1824, 2011 | 83 | 2011 |
| Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages X Luo, D Pires, JA Aínsa, B Gracia, N Duarte, S Mulhovo, E Anes, ... Journal of ethnopharmacology 146 (1), 417-422, 2013 | 81 | 2013 |
| Multidrug Resistance Reversal and Apoptosis Induction in Human Colon Cancer Cells by Some Flavonoids Present in Citrus Plants O Wesołowska, J Wiśniewski, K Środa-Pomianek, A Bielawska-Pohl, ... Journal of natural products 75 (11), 1896-1902, 2012 | 81 | 2012 |
| Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina C Ramalhete, G Spengler, A Martins, M Martins, M Viveiros, S Mulhovo, ... International Journal of Antimicrobial Agents 37 (1), 70-74, 2011 | 80 | 2011 |
| Enhancing macrocyclic diterpenes as multidrug-resistance reversers: Structure–Activity studies on jolkinol D derivatives M Reis, RJ Ferreira, MMM Santos, DJVA Dos Santos, J Molnár, ... Journal of Medicinal Chemistry 56 (3), 748-760, 2013 | 75 | 2013 |
| Induction of apoptosis in HuH-7 cancer cells by monoterpene and β-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegans TA Mansoor, RM Ramalho, S Mulhovo, CMP Rodrigues, MJU Ferreira Bioorganic & medicinal chemistry letters 19 (15), 4255-4258, 2009 | 72 | 2009 |
| Antiplasmodial activity of lignans and extracts from Pycnanthus angolensis M Abrantes, T Mil-Homens, N Duarte, D Lopes, P Cravo, ... Planta medica 74 (11), 1408-1412, 2008 | 70 | 2008 |
| Structure-function relationships in ABCG2: insights from molecular dynamics simulations and molecular docking studies RJ Ferreira, CA Bonito, MNDS Cordeiro, MJU Ferreira, DJVA Dos Santos Scientific reports 7 (1), 15534, 2017 | 67 | 2017 |
| Toward a Better Pharmacophore Description of P-Glycoprotein Modulators, Based on Macrocyclic Diterpenes from Euphorbia Species RJ Ferreira, DJVA Dos Santos, MJU Ferreira, RC Guedes Journal of chemical information and modeling 51 (6), 1315-1324, 2011 | 67 | 2011 |
