| Frequency modulation of ERK activation dynamics rewires cell fate H Ryu, M Chung, M Dobrzyński, D Fey, Y Blum, SS Lee, M Peter, ... Molecular systems biology 11 (11), 838, 2015 | 268 | 2015 |
| Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ... Cell systems 2 (1), 38-48, 2016 | 184 | 2016 |
| Elongation dynamics shape bursty transcription and translation M Dobrzyński, FJ Bruggeman Proceedings of the National Academy of Sciences 106 (8), 2583-2588, 2009 | 144 | 2009 |
| Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival PA Gagliardi, M Dobrzyński, MA Jacques, C Dessauges, P Ender, Y Blum, ... Developmental cell 56 (12), 1712-1726. e6, 2021 | 126 | 2021 |
| Spatial stochastic modelling of the phosphoenolpyruvate-dependent phosphotransferase (PTS) pathway in Escherichia coli JV Rodriguez, JA Kaandorp, M Dobrzyński, JG Blom Bioinformatics 22 (15), 1895-1901, 2006 | 119 | 2006 |
| Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise MR Birtwistle, J Rauch, A Kiyatkin, E Aksamitiene, M Dobrzyński, JB Hoek, ... BMC systems biology 6, 1-12, 2012 | 96 | 2012 |
| Computational methods for diffusion-influenced biochemical reactions M Dobrzyński, JV Rodríguez, JA Kaandorp, JG Blom Bioinformatics 23 (15), 1969-1977, 2007 | 76 | 2007 |
| Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis P Ender, PA Gagliardi, M Dobrzyński, A Frismantiene, C Dessauges, ... Developmental cell 57 (18), 2153-2167. e6, 2022 | 49 | 2022 |
| Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling Y Blum, J Mikelson, M Dobrzyński, H Ryu, MA Jacques, NL Jeon, ... Molecular systems biology 15 (11), e8947, 2019 | 43 | 2019 |
| Proteomics analysis of bladder cancer invasion: targeting EIF3D for therapeutic intervention A Latosinska, M Mokou, M Makridakis, W Mullen, J Zoidakis, V Lygirou, ... Oncotarget 8 (41), 69435, 2017 | 39 | 2017 |
| Polyubiquitin chain assembly and organisation determine the dynamics of protein activation and degradation LK Nguyen, M Dobrzynski, D Fey, BN Kholodenko Frontiers in Physiology, 0, 2014 | 39 | 2014 |
| Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses M Dobrzyński, LK Nguyen, MR Birtwistle, A von Kriegsheim, ... Journal of The Royal Society Interface 11 (98), 20140383, 2014 | 36 | 2014 |
| Optogenetic actuator–ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics C Dessauges, J Mikelson, M Dobrzyński, MA Jacques, A Frismantiene, ... Molecular systems biology 18 (6), e10670, 2022 | 34 | 2022 |
| Strategies for structuring interdisciplinary education in Systems Biology: an European perspective M Cvijovic, T Höfer, J Aćimović, L Alberghina, E Almaas, D Besozzi, ... NPJ systems biology and applications 2 (1), 1-7, 2016 | 29 | 2016 |
| Origins of stochastic intracellular processes and consequences for cell-to-cell variability and cellular survival strategies A Schwabe, M Dobrzyński, K Rybakova, P Verschure, FJ Bruggeman Methods in enzymology 500, 597-625, 2011 | 23 | 2011 |
| CODEX, a neural network approach to explore signaling dynamics landscapes MA Jacques, M Dobrzyński, PA Gagliardi, R Sznitman, O Pertz Molecular systems biology 17 (4), e10026, 2021 | 22 | 2021 |
| Automatic detection of spatio-temporal signaling patterns in cell collectives PA Gagliardi, B Grädel, MA Jacques, L Hinderling, P Ender, AR Cohen, ... Journal of Cell Biology 222 (10), 2023 | 16 | 2023 |
| Mining single-cell time-series datasets with Time Course Inspector M Dobrzyński, MA Jacques, O Pertz Bioinformatics 36 (6), 1968-1969, 2020 | 15 | 2020 |
| Mammalian protein expression noise: scaling principles and the implications for knockdown experiments MR Birtwistle, A Von Kriegsheim, M Dobrzyński, BN Kholodenko, W Kolch Molecular BioSystems 8 (11), 3068-3076, 2012 | 15 | 2012 |
| Combining activity profiling with advanced annotation to accelerate the discovery of natural products targeting oncogenic signaling in melanoma T Hell, A Rutz, L Dürr, M Dobrzyński, JK Reinhardt, T Lehner, M Keller, ... Journal of natural products 85 (6), 1540-1554, 2022 | 14 | 2022 |
Olivier PertzFull professor University of BernE-mail megerősítve itt: izb.unibe.ch
