Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain M Zouridakis, P Giastas, E Zarkadas, D Chroni-Tzartou, P Bregestovski, ... Nature structural & molecular biology 21 (11), 976-980, 2014 | 105 | 2014 |
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing I Evnouchidou, J Birtley, S Seregin, A Papakyriakou, E Zervoudi, ... The Journal of Immunology 189 (5), 2383-2392, 2012 | 99 | 2012 |
Structural basis for antigenic peptide recognition and processing by endoplasmic reticulum (ER) aminopeptidase 2 A Mpakali, P Giastas, N Mathioudakis, IM Mavridis, E Saridakis, ... Journal of Biological Chemistry 290 (43), 26021-26032, 2015 | 95 | 2015 |
Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer N Kouvatsos, P Giastas, D Chroni-Tzartou, C Poulopoulou, SJ Tzartos Proceedings of the National Academy of Sciences 113 (34), 9635-9640, 2016 | 60 | 2016 |
Crystal structure of the monomeric extracellular domain of α9 nicotinic receptor subunit in complex with α-conotoxin RgIA: Molecular dynamics insights into RgIA binding to … M Zouridakis, A Papakyriakou, IA Ivanov, IE Kasheverov, V Tsetlin, ... Frontiers in pharmacology 10, 474, 2019 | 50 | 2019 |
The structure of the 2[4Fe–4S] ferredoxin from Pseudomonas aeruginosa at 1.32-Å resolution: comparison with other high-resolution structures of ferredoxins and … P Giastas, N Pinotsis, G Efthymiou, M Wilmanns, P Kyritsis, JM Moulis, ... JBIC Journal of Biological Inorganic Chemistry 11, 445-458, 2006 | 50 | 2006 |
Molecular interaction of α-conotoxin RgIA with the rat α9α10 nicotinic acetylcholine receptor L Azam, A Papakyriakou, M Zouridakis, P Giastas, SJ Tzartos, ... Molecular pharmacology 87 (5), 855-864, 2015 | 49 | 2015 |
Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1 P Giastas, A Mpakali, A Papakyriakou, A Lelis, P Kokkala, M Neu, ... Proceedings of the National Academy of Sciences 116 (52), 26709-26716, 2019 | 47 | 2019 |
Ligand-induced conformational change of insulin-regulated aminopeptidase: insights on catalytic mechanism and active site plasticity A Mpakali, E Saridakis, K Harlos, Y Zhao, P Kokkala, D Georgiadis, ... Journal of Medicinal Chemistry 60 (7), 2963-2972, 2017 | 46 | 2017 |
Two putative polysaccharide deacetylases are required for osmotic stability and cell shape maintenance in Bacillus anthracis S Arnaouteli, P Giastas, A Andreou, M Tzanodaskalaki, C Aldridge, ... Journal of Biological Chemistry 290 (21), 13465-13478, 2015 | 43 | 2015 |
Molecular structures of the inclusion complexes β-cyclodextrin–1, 2-bis (4-aminophenyl) ethane and β-cyclodextrin–4, 4′-diaminobiphenyl; packing of dimeric β-cyclodextrin … P Giastas, K Yannakopoulou, IM Mavridis Structural Science 59 (2), 287-299, 2003 | 39 | 2003 |
Understanding structure–function relationships of the human neuronal acetylcholine receptor: insights from the first crystal structures of neuronal subunits P Giastas, M Zouridakis, SJ Tzartos British journal of pharmacology 175 (11), 1880-1891, 2018 | 38 | 2018 |
High-resolution crystal structure of endoplasmic reticulum aminopeptidase 1 with bound phosphinic transition-state analogue inhibitor P Giastas, M Neu, P Rowland, E Stratikos ACS Medicinal Chemistry Letters 10 (5), 708-713, 2019 | 36 | 2019 |
Insight into the protein and solvent contributions to the reduction potentials of [4Fe–4S]2+/+ clusters: crystal structures of the Allochromatium vinosum ferredoxin variants … E Saridakis, P Giastas, G Efthymiou, V Thoma, JM Moulis, P Kyritsis, ... JBIC Journal of Biological Inorganic Chemistry 14, 783-799, 2009 | 33 | 2009 |
Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors P Giastas, A Andreou, A Papakyriakou, D Koutsioulis, S Balomenou, ... Biochemistry 57 (5), 753-763, 2018 | 27 | 2018 |
Synthesis of 6-Mono-6-deoxy-β-cyclodextrins Substituted with Isomeric Aminobenzoic Acids. Structural Characterization, Conformational Preferences, and Self … K Eliadou, P Giastas, K Yannakopoulou, IM Mavridis The Journal of Organic Chemistry 68 (22), 8550-8557, 2003 | 26 | 2003 |
Inclusion compounds of plant growth regulators in cyclodextrins. V. 4-Chlorophenoxyacetic acid encapsulated in β-cyclodextrin and heptakis (2, 3, 6-tri-O-methyl)-β-cyclodextrin F Tsorteki, K Bethanis, N Pinotsis, P Giastas, D Mentzafos Structural Science 61 (2), 207-217, 2005 | 25 | 2005 |
Formation of a highly-ordered rigid multichromophoric 3D supramolecular network by combining ionic and coordination-driven self-assembly A Kaloudi-Chantzea, E Martinou, K Seintis, N Karakostas, P Giastas, ... Chemical Communications 52 (16), 3388-3391, 2016 | 23 | 2016 |
Structural basis of inhibition of insulin-regulated aminopeptidase by a macrocyclic peptidic inhibitor A Mpakali, E Saridakis, P Giastas, Z Maben, LJ Stern, M Larhed, ... ACS medicinal chemistry letters 11 (7), 1429-1434, 2020 | 22 | 2020 |
Crystal structures of ERAP2 complexed with inhibitors reveal pharmacophore requirements for optimizing inhibitor potency A Mpakali, P Giastas, R Deprez-Poulain, A Papakyriakou, D Koumantou, ... ACS Medicinal Chemistry Letters 8 (3), 333-337, 2017 | 22 | 2017 |