Accurate structure prediction of biomolecular interactions with AlphaFold 3 J Abramson, J Adler, J Dunger, R Evans, T Green, A Pritzel, ... Nature 630 (8016), 493-500, 2024 | 3177 | 2024 |
Simulating 500 million years of evolution with a language model T Hayes, R Rao, H Akin, NJ Sofroniew, D Oktay, Z Lin, R Verkuil, VQ Tran, ... Science, eads0018, 2025 | 180 | 2025 |
Programmed ribosomal frameshifting generates a copper transporter and a copper chaperone from the same gene S Meydan, D Klepacki, S Karthikeyan, T Margus, P Thomas, JE Jones, ... Molecular cell 65 (2), 207-219, 2017 | 101 | 2017 |
The AAA+ superfamily: a review of the structural and mechanistic principles of these molecular machines YA Khan, KI White, AT Brunger Critical reviews in biochemistry and molecular biology 57 (2), 156-187, 2022 | 95 | 2022 |
The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling T Girardi, S Vereecke, SO Sulima, Y Khan, L Fancello, JW Briggs, ... Leukemia 32 (3), 809-819, 2018 | 87 | 2018 |
Ablation of programmed− 1 ribosomal frameshifting in Venezuelan equine encephalitis virus results in attenuated neuropathogenicity JA Kendra, C de la Fuente, A Brahms, C Woodson, TM Bell, B Chen, ... Journal of virology 91 (3), 10.1128/jvi. 01766-16, 2017 | 53 | 2017 |
Structural and functional characterization of programmed ribosomal frameshift signals in West Nile virus strains reveals high structural plasticity among cis-acting RNA elements C Moomau, S Musalgaonkar, YA Khan, JE Jones, JD Dinman Journal of Biological Chemistry 291 (30), 15788-15795, 2016 | 46 | 2016 |
Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon YA Khan, I Jungreis, JC Wright, JM Mudge, JS Choudhary, AE Firth, ... BMC genetics 21, 1-16, 2020 | 36 | 2020 |
Evaluating ribosomal frameshifting in CCR5 mRNA decoding YA Khan, G Loughran, AL Steckelberg, K Brown, SJ Kiniry, H Stewart, ... Nature 604 (7906), E16-E23, 2022 | 28 | 2022 |
ROS regulate differentiation of visceralizing Leishmania species into the virulent amastigote form YA Khan, NW Andrews, B Mittra Parasitology open 4, e19, 2018 | 28 | 2018 |
Cryo-EM, protein engineering, and simulation enable the development of peptide therapeutics against acute myeloid leukemia K Zhang, N Horikoshi, S Li, AS Powers, MA Hameedi, GD Pintilie, ... ACS Central Science 8 (2), 214-222, 2022 | 12 | 2022 |
Leishmania amazonensis ferric iron reductase (LFR1) is a bifunctional enzyme: Unveiling a NADPH oxidase activity N Rocco-Machado, D Cosentino-Gomes, MT Nascimento, L Paes-Vieira, ... Free Radical Biology and Medicine 143, 341-353, 2019 | 12 | 2019 |
Quantification of intracellular growth inside macrophages is a fast and reliable method for assessing the virulence of Leishmania parasites A Sarkar, YA Khan, MF Laranjeira-Silva, NW Andrews, B Mittra Journal of Visualized Experiments: Jove, 57486, 2018 | 11 | 2018 |
Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimus JW Briggs, L Ren, KR Chakrabarti, YC Tsai, AM Weissman, RJ Hansen, ... Plos one 12 (9), e0185089, 2017 | 9 | 2017 |
Lack of evidence for ribosomal frameshifting in ATP7B mRNA decoding G Loughran, AD Fedorova, YA Khan, JF Atkins, PV Baranov Molecular Cell 82 (19), 3745-3749. e2, 2022 | 8 | 2022 |
Sensory deficit screen identifies nsf mutation that differentially affects SNARE recycling and quality control Y Gao, YA Khan, W Mo, KI White, M Perkins, RA Pfuetzner, JG Trapani, ... Cell reports 42 (4), 2023 | 6 | 2023 |
Sec18 side-loading is essential for universal SNARE recycling across cellular contexts YA Khan, KI White, RA Pfuetzner, B Singal, L Esquivies, G Mckenzie, ... bioRxiv, 2024 | 1 | 2024 |
covLLM: Large language models for COVID-19 biomedical literature YA Khan, C Hokia, J Xu, B Ehlert arXiv preprint arXiv:2306.04926, 2023 | 1 | 2023 |
Response to: Lack of evidence for ribosomal frameshifting in ATP7B mRNA decoding S Meydan, D Klepacki, S Karthikeyan, T Margus, P Thomas, JE Jones, ... Molecular Cell 82 (19), 3523, 2022 | 1 | 2022 |
Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission KI White, YA Khan, K Qiu, A Balaji, S Couoh-Cardel, L Esquivies, ... bioRxiv, 2024.10. 11.617886, 2024 | | 2024 |