Cikkek nyilvánosan hozzáférhető megbízással - Anastasia MpakaliTovábbi információ
Valahol hozzáférhető: 15
Crystal structure of insulin-regulated aminopeptidase with bound substrate analogue provides insight on antigenic epitope precursor recognition and processing
A Mpakali, E Saridakis, K Harlos, Y Zhao, A Papakyriakou, P Kokkala, ...
The Journal of Immunology 195 (6), 2842-2851, 2015
Megbízások: UK Medical Research Council, Wellcome Trust
Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1
P Giastas, A Mpakali, A Papakyriakou, A Lelis, P Kokkala, M Neu, ...
Proceedings of the National Academy of Sciences 116 (52), 26709-26716, 2019
Megbízások: European Molecular Biology Laboratory, European Commission
Ligand-induced conformational change of insulin-regulated aminopeptidase: insights on catalytic mechanism and active site plasticity
A Mpakali, E Saridakis, K Harlos, Y Zhao, P Kokkala, D Georgiadis, ...
Journal of Medicinal Chemistry 60 (7), 2963-2972, 2017
Megbízások: UK Medical Research Council, Wellcome Trust
Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)
D Koumantou, E Barnea, A Martin-Esteban, Z Maben, A Papakyriakou, ...
Cancer Immunology, Immunotherapy 68, 1245-1261, 2019
Megbízások: US National Institutes of Health
Critical role of interdomain interactions in the conformational change and catalytic mechanism of endoplasmic reticulum aminopeptidase 1
A Stamogiannos, Z Maben, A Papakyriakou, A Mpakali, P Kokkala, ...
Biochemistry 56 (10), 1546-1558, 2017
Megbízások: US Department of Energy, US National Institutes of Health
Molecular pathways for antigenic peptide generation by ER aminopeptidase 1
A Mpakali, Z Maben, LJ Stern, E Stratikos
Molecular immunology 113, 50-57, 2019
Megbízások: US National Institutes of Health
Structural basis of inhibition of insulin-regulated aminopeptidase by a macrocyclic peptidic inhibitor
A Mpakali, E Saridakis, P Giastas, Z Maben, LJ Stern, M Larhed, ...
ACS medicinal chemistry letters 11 (7), 1429-1434, 2020
Megbízások: US Department of Energy, US National Institutes of Health
A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1
G Mavridis, R Arya, A Domnick, J Zoidakis, M Makridakis, A Vlahou, ...
Journal of Biological Chemistry 295 (21), 7193-7210, 2020
Megbízások: US National Institutes of Health, German Research Foundation, European …
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis
V Camberlein, C Fléau, P Sierocki, L Li, R Gealageas, D Bosc, ...
Angewandte Chemie 134 (39), e202203560, 2022
Megbízások: US National Institutes of Health, Helmholtz Association, National Institute …
Discovery of selective nanomolar inhibitors for insulin-regulated aminopeptidase based on α-hydroxy-β-amino acid derivatives of bestatin
D Vourloumis, I Mavridis, A Athanasoulis, I Temponeras, D Koumantou, ...
Journal of medicinal chemistry 65 (14), 10098-10117, 2022
Megbízások: European Commission, Agence Nationale de la Recherche
Mechanisms of allosteric inhibition of insulin-regulated aminopeptidase
A Mpakali, I Barla, L Lu, KM Ramesh, N Thomaidis, LJ Stern, P Giastas, ...
Journal of Molecular Biology 436 (6), 168449, 2024
Megbízások: US Department of Energy, US National Institutes of Health
Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties
G Georgaki, A Mpakali, M Trakada, A Papakyriakou, E Stratikos
Frontiers in Immunology 15, 1415964, 2024
Megbízások: European Commission
Stabilization of the open conformation οf insulin‐regulated aminopeptidase by a novel substrate‐selective small‐molecule inhibitor
A Mpakali, G Georgaki, A Buson, AD Findlay, JS Foot, FX Mauvais, ...
Protein Science 33 (9), e5151, 2024
Megbízások: European Commission
Stabilization of the open conformation of Insulin-Regulated Aminopeptidase by a novel substrate-selective small molecule inhibitor
A Mpakali, G Georgaki, A Buson, AD Findlay, JS Foot, FX Mauvais, ...
bioRxiv, 2024.06. 04.597268, 2024
Megbízások: European Commission
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G Mavridis, R Arya, A Domnick, J Zoidakis, M Makridakis, A Vlahou, ...
Megbízások: German Research Foundation, European Commission
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