| Cyclin A in cell cycle control and cancer CH Yam, TK Fung, RYC Poon Cellular and Molecular Life Sciences CMLS 59, 1317-1326, 2002 | 670 | 2002 |
| Sorafenib treatment of FLT3-ITD+ acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the … CH Man, TK Fung, C Ho, HHC Han, HCH Chow, ACH Ma, WWL Choi, ... Blood, The Journal of the American Society of Hematology 119 (22), 5133-5143, 2012 | 356 | 2012 |
| A roller coaster ride with the mitotic cyclins TK Fung, RYC Poon Seminars in cell & developmental biology 16 (3), 335-342, 2005 | 278 | 2005 |
| Targeting aberrant epigenetic networks mediated by PRMT1 and KDM4C in acute myeloid leukemia N Cheung, TK Fung, BB Zeisig, K Holmes, JK Rane, KA Mowen, MG Finn, ... Cancer cell 29 (1), 32-48, 2016 | 183 | 2016 |
| Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors MT Esposito, L Zhao, TK Fung, JK Rane, A Wilson, N Martin, J Gil, ... Nature medicine 21 (12), 1481-1490, 2015 | 174 | 2015 |
| HOTTIP lncRNA promotes hematopoietic stem cell self-renewal leading to AML-like disease in mice H Luo, G Zhu, J Xu, Q Lai, B Yan, Y Guo, TK Fung, BB Zeisig, Y Cui, J Zha, ... Cancer cell 36 (6), 645-659. e8, 2019 | 154 | 2019 |
| Specialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase–promoting factor TK Fung, HT Ma, RYC Poon Molecular biology of the cell 18 (5), 1861-1873, 2007 | 133 | 2007 |
| Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins TK Fung, WY Siu, CH Yam, A Lau, RYC Poon Journal of Biological Chemistry 277 (38), 35140-35149, 2002 | 103 | 2002 |
| Ubiquitination of p53 at multiple sites in the DNA-binding domain WM Chan, MC Mak, TK Fung, A Lau, WY Siu, RYC Poon Molecular cancer research 4 (1), 15-25, 2006 | 99 | 2006 |
| HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia H Luo, G Zhu, MA Eshelman, TK Fung, Q Lai, F Wang, BB Zeisig, ... Molecular cell 82 (4), 833-851. e11, 2022 | 78 | 2022 |
| Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia CH Man, TK Fung, H Wan, CY Cher, A Fan, N Ng, C Ho, TSK Wan, ... Blood, The Journal of the American Society of Hematology 125 (25), 3928-3936, 2015 | 60 | 2015 |
| DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin–CDC2 complexes, and reverses cells to interphase JPH Chow, WY Siu, TK Fung, WM Chan, A Lau, T Arooz, CP Ng, ... Molecular biology of the cell 14 (10), 3989-4002, 2003 | 59 | 2003 |
| The N-terminal regulatory domain of cyclin A contains redundant ubiquitination targeting sequences and acceptor sites TK Fung, CH Yam, RYC Poon Cell Cycle 4 (10), 1411-1420, 2005 | 53 | 2005 |
| Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies MF Arteaga, JH Mikesch, TK Fung, CWE So British journal of cancer 112 (3), 413-418, 2015 | 34 | 2015 |
| Biophysical characterization of hematopoietic cells from normal and leukemic sources with distinct primitiveness Y Tan, TK Fung, H Wan, K Wang, AYH Leung, D Sun Applied Physics Letters 99 (8), 2011 | 34 | 2011 |
| Selective treatment of mixed-lineage leukemia leukemic stem cells through targeting glycogen synthase kinase 3 and the canonical Wnt/β-catenin pathway TK Fung, A Gandillet, CWE So Current opinion in hematology 19 (4), 280-286, 2012 | 32 | 2012 |
| Transcriptional memory of cells of origin overrides β‐catenin requirement of MLL cancer stem cells T Siriboonpiputtana, BB Zeisig, M Zarowiecki, TK Fung, M Mallardo, ... The EMBO journal 36 (21), 3139-3155, 2017 | 29 | 2017 |
| Overcoming treatment resistance in acute promyelocytic leukemia and beyond TK Fung, CWE So Oncotarget 4 (8), 1128, 2013 | 29 | 2013 |
| Methionine aminopeptidase 2 is required for HSC initiation and proliferation ACH Ma, TK Fung, RHC Lin, MIS Chung, D Yang, SC Ekker, AYH Leung Blood, The Journal of the American Society of Hematology 118 (20), 5448-5457, 2011 | 29 | 2011 |
| Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia BB Zeisig, TK Fung, M Zarowiecki, CT Tsai, H Luo, B Stanojevic, C Lynn, ... Science Translational Medicine 13 (582), eabc4822, 2021 | 23 | 2021 |
Randy Yat Choi PoonChair Professor, Division of Life Science, The Hong Kong University of Science and TechnologyE-mail megerősítve itt: ust.hk
