| Overview on the Rule of Five MP Pollastri Current protocols in pharmacology 49 (1), 9.12. 1-9.12. 8, 2010 | 311 | 2010 |
| Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production MM Lowe, JE Mold, B Kanwar, Y Huang, A Louie, MP Pollastri, C Wang, ... PloS one 9 (2), e87877, 2014 | 150 | 2014 |
| Repurposing strategies for tropical disease drug discovery DM Klug, MH Gelb, MP Pollastri Bioorganic & Medicinal Chemistry Letters 26 (11), 2569-2576, 2016 | 118 | 2016 |
| The aryl hydrocarbon receptor is a critical regulator of tissue factor stability and an antithrombotic target in uremia S Shivanna, K Kolandaivelu, M Shashar, M Belghasim, L Al-Rabadi, ... Journal of the American Society of Nephrology 27 (1), 189-201, 2016 | 116 | 2016 |
| Target repurposing for neglected diseases MP Pollastri, RK Campbell Future medicinal chemistry 3 (10), 1307-1315, 2011 | 96 | 2011 |
| The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing R Diaz-Gonzalez, FM Kuhlmann, C Galan-Rodriguez, LM da Silva, ... PLoS neglected tropical diseases 5 (8), e1297, 2011 | 95 | 2011 |
| Kinase scaffold repurposing for neglected disease drug discovery: Discovery of an efficacious, lapatanib-derived lead compound for trypanosomiasis G Patel, CE Karver, R Behera, PJ Guyett, C Sullenberger, P Edwards, ... Journal of medicinal chemistry 56 (10), 3820-3832, 2013 | 93 | 2013 |
| Ligand deconstruction: Why some fragment binding positions are conserved and others are not D Kozakov, DR Hall, S Jehle, L Luo, SO Ochiana, EV Jones, M Pollastri, ... Proceedings of the National Academy of Sciences 112 (20), E2585-E2594, 2015 | 86 | 2015 |
| Kinases as druggable targets in trypanosomatid protozoan parasites C Merritt, LE Silva, AL Tanner, K Stuart, MP Pollastri Chemical reviews 114 (22), 11280-11304, 2014 | 84 | 2014 |
| Antitrypanosomal lead discovery: identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth G Andriani, E Amata, J Beatty, Z Clements, BJ Coffey, G Courtemanche, ... Journal of medicinal chemistry 56 (6), 2556-2567, 2013 | 79 | 2013 |
| Protozoan parasite growth inhibitors discovered by cross-screening yield potent scaffolds for lead discovery W Devine, JL Woodring, U Swaminathan, E Amata, G Patel, J Erath, ... Journal of medicinal chemistry 58 (14), 5522-5537, 2015 | 76 | 2015 |
| Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum S Absalon, K Blomqvist, RM Rudlaff, TJ DeLano, MP Pollastri, JD Dvorin MBio 9 (1), 10.1128/mbio. 00130-18, 2018 | 73 | 2018 |
| 2-Benzoylbenzoic acid: A photolabile mask for alcohols and thiols PB Jones, MP Pollastri, NA Porter The Journal of Organic Chemistry 61 (26), 9455-9461, 1996 | 73 | 1996 |
| The future of drug repositioning: old drugs, new opportunities TL Doan, M Pollastri, MA Walters, GI Georg Annual reports in medicinal chemistry 46, 385-401, 2011 | 70 | 2011 |
| Fexinidazole: a new drug for African sleeping sickness on the horizon MP Pollastri Trends in parasitology 34 (3), 178-179, 2018 | 67 | 2018 |
| Loss of the tert-butyloxycarbonyl (Boc) protecting group under basic conditions TP Curran, MP Pollastri, SM Abelleira, RJ Messier, TA McCollum, ... Tetrahedron Letters 35 (30), 5409-5412, 1994 | 65 | 1994 |
| Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening … R Diaz, SA Luengo-Arratta, JD Seixas, E Amata, W Devine, ... PLoS Neglected Tropical Diseases 8 (10), e3253, 2014 | 63 | 2014 |
| Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery G Patel, NE Roncal, PJ Lee, SE Leed, J Erath, A Rodriguez, RJ Sciotti, ... MedChemComm 5 (5), 655-658, 2014 | 61 | 2014 |
| Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness ND Bland, C Wang, C Tallman, AE Gustafson, Z Wang, TD Ashton, ... Journal of medicinal chemistry 54 (23), 8188-8194, 2011 | 61 | 2011 |
| Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1) E Amata, ND Bland, RK Campbell, MP Pollastri Tetrahedron letters 56 (21), 2832-2835, 2015 | 56 | 2015 |
