Cikkek nyilvánosan hozzáférhető megbízással - Mark S.P. SansomTovábbi információ
Sehol sem hozzáférhető: 8
Áttekintés
Lipid-dependent regulation of ion channels and G protein–coupled receptors: insights from structures and simulations
AL Duncan, W Song, MSP Sansom
Annual review of pharmacology and toxicology 60 (1), 31-50, 2020
Megbízások: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Áttekintés
Membrane perturbation by carbon nanotube insertion: pathways to internalization
M Lelimousin, MSP Sansom
Small 9 (21), 3639-3646, 2013
Megbízások: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Áttekintés
Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations
PJ Stansfeld, A Grottesi, ZA Sands, MSP Sansom, P Gedeck, M Gosling, ...
Biochemistry 47 (28), 7414-7422, 2008
Megbízások: British Heart Foundation
Áttekintés
Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a “bottleneck” in the pore
Y Norimatsu, A Ivetac, C Alexander, J Kirkham, N O’Donnell, DC Dawson, ...
Biochemistry 51 (11), 2199-2212, 2012
Megbízások: US National Institutes of Health
Áttekintés
Designing a hydrophobic barrier within biomimetic nanopores
JL Trick, EJ Wallace, H Bayley, MSP Sansom
ACS nano 8 (11), 11268-11279, 2014
Megbízások: UK Biotechnology and Biological Sciences Research Council
Áttekintés
Computational virology: molecular simulations of virus dynamics and interactions
EE Jefferys, MSP Sansom
Physical Virology: Virus Structure and Mechanics, 201-233, 2019
Megbízások: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Áttekintés
Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery
P Conflitti, E Lyman, MSP Sansom, PW Hildebrand, H Gutiérrez-de-Terán, ...
Nature Reviews Drug Discovery, 1-25, 2025
Megbízások: UK Medical Research Council, European Commission
Áttekintés
Identification and Characterization of Specific Protein–Lipid Interactions Using Molecular Simulation
RA Corey, MSP Sansom, PJ Stansfeld
Computational Design of Membrane Proteins, 121-139, 2021
Megbízások: UK Biotechnology and Biological Sciences Research Council
Valahol hozzáférhető: 220
Áttekintés
Computational modeling of realistic cell membranes
SJ Marrink, V Corradi, PCT Souza, HI Ingolfsson, DP Tieleman, ...
Chemical reviews 119 (9), 6184-6226, 2019
Megbízások: US Department of Energy, Canadian Institutes of Health Research, Natural …
Áttekintés
Structural basis of Smoothened regulation by its extracellular domains
EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ...
Nature 535 (7613), 517-522, 2016
Megbízások: US National Science Foundation, Ford Foundation, US National Institutes of …
Áttekintés
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac
YY Dong, ACW Pike, A Mackenzie, C McClenaghan, P Aryal, L Dong, ...
Science 347 (6227), 1256-1259, 2015
Megbízások: US National Institutes of Health, Genome Canada, UK Biotechnology and …
Áttekintés
Hydrophobic gating in ion channels
P Aryal, MSP Sansom, SJ Tucker
Journal of molecular biology 427 (1), 121-130, 2015
Megbízások: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Áttekintés
MemProtMD: automated insertion of membrane protein structures into explicit lipid membranes
PJ Stansfeld, JE Goose, M Caffrey, EP Carpenter, JL Parker, S Newstead, ...
Structure 23 (7), 1350-1361, 2015
Megbízások: Science Foundation Ireland, UK Biotechnology and Biological Sciences …
Áttekintés
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states
CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ...
Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013
Megbízások: Canadian Institutes of Health Research, Genome Canada, UK Biotechnology and …
Áttekintés
PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
HY Yen, KK Hoi, I Liko, G Hedger, MR Horrell, W Song, D Wu, P Heine, ...
Nature 559 (7714), 423-427, 2018
Megbízások: Swiss National Science Foundation, UK Biotechnology and Biological Sciences …
Áttekintés
Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context
RAF Reithmeier, JR Casey, AC Kalli, MSP Sansom, Y Alguel, S Iwata
Biochimica et biophysica acta (BBA)-Biomembranes 1858 (7), 1507-1532, 2016
Megbízások: UK Engineering and Physical Sciences Research Council
Áttekintés
Lipid clustering correlates with membrane curvature as revealed by molecular simulations of complex lipid bilayers
H Koldsø, D Shorthouse, J Hélie, MSP Sansom
PLoS computational biology 10 (10), e1003911, 2014
Megbízások: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Áttekintés
Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria
P Rassam, NA Copeland, O Birkholz, C Tóth, M Chavent, AL Duncan, ...
Nature 523 (7560), 333-336, 2015
Megbízások: German Research Foundation, UK Biotechnology and Biological Sciences …
Áttekintés
The pore structure and gating mechanism of K2P channels
PL Piechotta, M Rapedius, PJ Stansfeld, MK Bollepalli, G Erhlich, ...
The EMBO journal 30 (17), 3607-3619, 2011
Megbízások: German Research Foundation
Áttekintés
Multiscale methods for macromolecular simulations
P Sherwood, BR Brooks, MSP Sansom
Current opinion in structural biology 18 (5), 630-640, 2008
Megbízások: US National Institutes of Health
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