| Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19 RT Eastman, JS Roth, KR Brimacombe, A Simeonov, M Shen, S Patnaik, ... ACS central Science 6 (5), 672-683, 2020 | 1031 | 2020 |
| A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase NJ Martinez, RR Asawa, MG Cyr, A Zakharov, DJ Urban, JS Roth, ... Scientific reports 8 (1), 9472, 2018 | 100 | 2018 |
| Discovery of orally bioavailable, quinoline-based aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with potent cellular activity SM Yang, NJ Martinez, A Yasgar, C Danchik, C Johansson, Y Wang, ... Journal of medicinal chemistry 61 (11), 4883-4903, 2018 | 88 | 2018 |
| Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space SE Kearney, G Zahoránszky-Kőhalmi, KR Brimacombe, MJ Henderson, ... ACS central science 4 (12), 1727-1741, 2018 | 42 | 2018 |
| PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia J Li, J Hlavka-Zhang, JH Shrimp, C Piper, D Dupéré-Richér, JS Roth, ... Cancer Discovery 12 (1), 186-203, 2022 | 35 | 2022 |
| Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation MI Maron, AD Casill, V Gupta, JS Roth, S Sidoli, CC Query, MJ Gamble, ... Elife 11, e72867, 2022 | 28 | 2022 |
| Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter RW Robey, AN Robinson, F Ali-Rahmani, LM Huff, S Lusvarghi, S Vahedi, ... Scientific Reports 11 (1), 24150, 2021 | 22 | 2021 |
| The combination of trametinib and ganitumab is effective in RAS-mutated PAX-fusion negative rhabdomyosarcoma models KE Hebron, X Wan, JS Roth, DJ Liewehr, NE Sealover, WJE Frye, A Kim, ... Clinical Cancer Research 29 (2), 472-487, 2023 | 9 | 2023 |
| Keeping it clean: the cell culture quality control experience at the National Center for Advancing Translational Sciences JS Roth, TD Lee, DM Cheff, ML Gosztyla, RR Asawa, C Danchik, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (5), 491-497, 2020 | 7 | 2020 |
| Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma S Stauffer, JS Roth, ER Hernandez, JT Kowalczyk, NE Sealover, ... Cancers 16 (13), 2320, 2024 | 2 | 2024 |
| Evaluation of SULT1A1-activated alkylators as cytotoxic agents against liver cancer cells K Kong, W Zhao, JH Shrimp, M Vava, R Sinha, S Sharma, TD Lee, ... | | 2024 |
| Birinapant selectively enhances immunotoxin‐mediated killing of cancer cells conditional on the IAP protein levels within target cells A Antignani, MT Bilotta, JS Roth, DJ Urban, M Shen, MD Hall, ... The FASEB Journal 37 (12), e23292, 2023 | | 2023 |
| Synergy between IAP inhibitors and a cytotoxic antibody-based chimeric protein D Antignani, DJ Urban, JS Roth, MD Hall, DJ Fitzgerald EUROPEAN JOURNAL OF CANCER 103, E69-E70, 2018 | | 2018 |
Matthew D HallNational Center for Advancing Translational Sciences (NCATS)E-mail megerősítve itt: mail.nih.gov