Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation D Wrapp, N Wang, KS Corbett, JA Goldsmith, CL Hsieh, O Abiona, ... Science 367 (6483), 1260-1263, 2020 | 10443 | 2020 |
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ... Science 369 (6510), 1501-1505, 2020 | 1234 | 2020 |
Beyond shielding: the roles of glycans in the SARS-CoV-2 spike protein L Casalino, Z Gaieb, JA Goldsmith, CK Hjorth, AC Dommer, AM Harbison, ... ACS central science 6 (10), 1722-1734, 2020 | 923 | 2020 |
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ... Science translational medicine 13 (593), eabf1906, 2021 | 453 | 2021 |
A glycan gate controls opening of the SARS-CoV-2 spike protein T Sztain, SH Ahn, AT Bogetti, L Casalino, JA Goldsmith, E Seitz, ... Nature chemistry 13 (10), 963-968, 2021 | 346 | 2021 |
Stabilized coronavirus spike stem elicits a broadly protective antibody CL Hsieh, AP Werner, SR Leist, LJ Stevens, E Falconer, JA Goldsmith, ... Cell reports 37 (5), 2021 | 81 | 2021 |
Expression and characterization of SARS-CoV-2 spike proteins JM Schaub, CW Chou, HC Kuo, K Javanmardi, CL Hsieh, J Goldsmith, ... Nature protocols 16 (11), 5339-5356, 2021 | 55 | 2021 |
Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner N de Zavalia, K Schoettner, JA Goldsmith, P Solis, S Ferraro, G Parent, ... Communications biology 4 (1), 1227, 2021 | 23 | 2021 |
Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes JA Goldsmith, AM DiVenere, JA Maynard, JS McLellan PLoS pathogens 17 (9), e1009920, 2021 | 21 | 2021 |
Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin JA Goldsmith, AM DiVenere, JA Maynard, JS McLellan Cell reports 40 (7), 2022 | 18 | 2022 |
Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain A Frederick, J Goldsmith, N de Zavalia, S Amir PLoS One 12 (4), e0176279, 2017 | 17 | 2017 |
Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer M Zehner, M Alt, A Ashurov, JA Goldsmith, R Spies, N Weiler, J Lerma, ... Immunity 56 (11), 2602-2620. e10, 2023 | 12 | 2023 |
Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation MR Sponholtz, PO Byrne, AG Lee, AR Ramamohan, JA Goldsmith, ... Proceedings of the National Academy of Sciences 121 (37), e2404250121, 2024 | 7 | 2024 |
Blockade of the adenylate cyclase toxin synergizes with opsonizing antibodies to protect mice against Bordetella pertussis AM DiVenere, D Amengor, RP Silva, JA Goldsmith, JS McLellan, ... Mbio 13 (4), e01527-22, 2022 | 5 | 2022 |
Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin JA Goldsmith, V Dewar, P Hermand, N Blais, JS McLellan Journal of Bacteriology 205 (4), e00456-22, 2023 | 3 | 2023 |
A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin–independent cell penetration A Osickova, S Knoblochova, L Bumba, P Man, Z Kalaninova, ... Journal of Biological Chemistry 299 (8), 2023 | 2 | 2023 |
Structural Basis for Antibody Neutralization of Pertussis Toxin JA Goldsmith, AW Nguyen, RE Wilen, W Wijagkanalan, JS McLellan, ... bioRxiv, 2024 | | 2024 |
Structural basis for receptor binding and antibody-mediated neutralization by Bordetella adenylate cyclase toxin JA Goldsmith | | 2023 |
Engineered coronavirus spike (s) protein and methods of use thereof J McLellan, J Maynard, A Chasse, I Finkelstein, M Javanmardi, J Schaub, ... US Patent App. 18/000,112, 2023 | | 2023 |