| Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male … KH Clodfelter, MG Holloway, P Hodor, SH Park, WJ Ray, DJ Waxman Molecular endocrinology 20 (6), 1333-1351, 2006 | 249 | 2006 |
| Predictome: a database of putative functional links between proteins JC Mellor, I Yanai, KH Clodfelter, J Mintseris, C DeLisi Nucleic Acids Research 30 (1), 306-309, 2002 | 205 | 2002 |
| Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis A Ahluwalia, KH Clodfelter, DJ Waxman Molecular Endocrinology 18 (3), 747-760, 2004 | 174 | 2004 |
| Optimal clustering for detecting near-native conformations in protein docking D Kozakov, KH Clodfelter, S Vajda, CJ Camacho Biophysical journal 89 (2), 867-875, 2005 | 160 | 2005 |
| Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors X Zheng, P Bauer, T Baumeister, AJ Buckmelter, M Caligiuri, ... Journal of medicinal chemistry 56 (16), 6413-6433, 2013 | 136* | 2013 |
| Identification of substrate binding sites in enzymes by computational solvent mapping M Silberstein, S Dennis, L Brown III, T Kortvelyesi, K Clodfelter, S Vajda Journal of molecular biology 332 (5), 1095-1113, 2003 | 100 | 2003 |
| Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis KH Clodfelter, GD Miles, V Wauthier, MG Holloway, X Zhang, P Hodor, ... Physiological genomics 31 (1), 63-74, 2007 | 79 | 2007 |
| Identification of amides derived from 1H-pyrazolo [3, 4-b] pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT) X Zheng, KW Bair, P Bauer, T Baumeister, KK Bowman, AJ Buckmelter, ... Bioorganic & medicinal chemistry letters 23 (20), 5488-5497, 2013 | 44 | 2013 |
| Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties J Gunzner-Toste, G Zhao, P Bauer, T Baumeister, AJ Buckmelter, ... Bioorganic & Medicinal Chemistry Letters 23 (12), 3531-3538, 2013 | 43 | 2013 |
| Computational solvent mapping reveals the importance of local conformational changes for broad substrate specificity in mammalian cytochromes P450 KH Clodfelter, DJ Waxman, S Vajda Biochemistry 45 (31), 9393-9407, 2006 | 42 | 2006 |
| Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility M Zak, BM Liederer, D Sampath, P Yuen, KW Bair, T Baumeister, ... Bioorganic & medicinal chemistry letters 25 (3), 529-541, 2015 | 32 | 2015 |
| Compounds and compositions for the inhibition of NAMPT KW Bair, T Baumeister, AJ Buckmelter, KH Clodfelter, B Han, J Lin, ... US Patent 9,169,209, 2015 | 31* | 2015 |
| Novel compounds and compositions for the inhibition of nampt KW Bair, TR Baumeister, AJ Buckmelter, KH Clodfelter, P Dragovich, ... US Patent App. 13/820,497, 2014 | 26 | 2014 |
| Compounds and compositions for the inhibition of NAMPT KW Bair, TR Baumeister, AJ Buckmelter, KH Clodfelter, P Dragovich, ... US Patent 10,272,072, 2019 | 24 | 2019 |
| Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors X Zheng, T Baumeister, AJ Buckmelter, M Caligiuri, KH Clodfelter, B Han, ... Bioorganic & medicinal chemistry letters 24 (1), 337-343, 2014 | 22 | 2014 |
| Amido-benzyl sulfone and sulfoxide derivates KW Bair, TR Baumeister, AJ Buckmelter, KH Clodfelter, P Dragovich, ... US Patent 10,696,692, 2020 | 21 | 2020 |
| PRECISE: a database of predicted and consensus interaction sites in enzymes SH Sheu, DR Lancia, KH Clodfelter, MR Landon, S Vajda Nucleic acids research 33 (suppl_1), D206-D211, 2005 | 18 | 2005 |
| Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT) KW Bair, TR Baumeister, AJ Buckmelter, KH Clodfelter, B Han, JD Kuntz, ... US Patent 9,555,039, 2017 | 15 | 2017 |
| Piperidine Derivatives And Compositions For the Inhibition Of Nicotinamide Phosphoribosyltransferase (NAMPT) KW Bair, T Baumeister, AJ Buckmelter, KH Clodfelter, B Han, JD Kuntz, ... US Patent App. 15/419,727, 2017 | 11 | 2017 |
| Sex-dependent liver gene expression is extensive and largely dependent upon STAT5b: STAT5b-dependent activation of male genes and repression of female genes revealed by … KH Clodfelter, MG Holloway, P Hodor, SH Park, WJ Ray, DJ Waxman Mol Endocrinol 20, 1333-1351, 2006 | 11 | 2006 |
Sandor VajdaProfessor of Biomedical Engineering, Boston UniversityE-mail megerősítve itt: bu.edu