Bone disease in multiple myeloma: pathophysiology and management A Hameed, JJ Brady, P Dowling, M Clynes, P O'Gorman Cancer growth and metastasis 7, CGM. S16817, 2014 | 253 | 2014 |
Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of disease‐specific biomarkers P Dowling, M Clynes Proteomics 11 (4), 794-804, 2011 | 194 | 2011 |
Proteomic approaches for serum biomarker discovery in cancer P Maurya, P Meleady, P Dowling, M Clynes Anticancer research 27 (3A), 1247-1255, 2007 | 169 | 2007 |
Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression … P Dowling, R Wormald, P Meleady, M Henry, A Curran, M Clynes Journal of proteomics 71 (2), 168-175, 2008 | 164 | 2008 |
MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines MK Muniyappa, P Dowling, M Henry, P Meleady, P Doolan, P Gammell, ... European journal of cancer 45 (17), 3104-3118, 2009 | 149 | 2009 |
Proteome analysis of the dystrophin‐deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP P Doran, G Martin, P Dowling, H Jockusch, K Ohlendieck Proteomics 6 (16), 4610-4621, 2006 | 131 | 2006 |
Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle K Culligan, N Banville, P Dowling, K Ohlendieck Journal of applied physiology 92 (2), 435-445, 2002 | 130 | 2002 |
Targeting proteotoxic stress in cancer: a review of the role that protein quality control pathways play in oncogenesis M Ho Zhi Guang, EL Kavanagh, LP Dunne, P Dowling, L Zhang, ... Cancers 11 (1), 66, 2019 | 112 | 2019 |
RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation N Walsh, AM Larkin, N Swan, K Conlon, P Dowling, R McDermott, ... Cancer letters 306 (2), 180-189, 2011 | 110 | 2011 |
Proteomic analysis of isolated membrane fractions from superinvasive cancer cells P Dowling, P Meleady, A Dowd, M Henry, S Glynn, M Clynes Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1774 (1), 93-101, 2007 | 109 | 2007 |
Subproteomics analysis of Ca2+‐binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle P Doran, P Dowling, J Lohan, K McDonnell, S Poetsch, K Ohlendieck European Journal of Biochemistry 271 (19), 3943-3952, 2004 | 108 | 2004 |
Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression ST Aherne, SF Madden, DJ Hughes, B Pardini, A Naccarati, M Levy, ... BMC cancer 15, 1-13, 2015 | 104 | 2015 |
The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro O Piskareva, H Harvey, J Nolan, R Conlon, L Alcock, P Buckley, ... Cancer letters 364 (2), 142-155, 2015 | 98 | 2015 |
Analysis of acute‐phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer P Dowling, C Clarke, K Hennessy, B Torralbo‐Lopez, J Ballot, J Crown, ... International journal of cancer 131 (4), 911-923, 2012 | 97 | 2012 |
Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells EL Kavanagh, S Lindsay, M Halasz, LC Gubbins, K Weiner-Gorzel, ... Oncogenesis 6 (10), e388-e388, 2017 | 93 | 2017 |
2‐D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course‐dependent remodelling in response to 14 consecutive days of endurance exercise … B Egan, P Dowling, PL O'Connor, M Henry, P Meleady, JR Zierath, ... Proteomics 11 (8), 1413-1428, 2011 | 93 | 2011 |
2‐D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins P Dowling, L O'Driscoll, P Meleady, M Henry, S Roy, J Ballot, M Moriarty, ... Electrophoresis 28 (23), 4302-4310, 2007 | 93 | 2007 |
Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy P Dowling, P Doran, K Ohlendieck Biochemical Journal 379 (2), 479-488, 2004 | 86 | 2004 |
Drug resistance in cancer–searching for mechanisms, markers and therapeutic agents R O'Connor, M Clynes, P Dowling, N O'Donovan, L O'Driscoll Expert opinion on drug metabolism & toxicology 3 (6), 805-817, 2007 | 82 | 2007 |
Identification of pancreatic cancer invasion-related proteins by proteomic analysis N Walsh, N O'Donovan, S Kennedy, M Henry, P Meleady, M Clynes, ... Proteome science 7, 1-14, 2009 | 79 | 2009 |