| Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease A Duvoix, J Dickens, I Haq, D Mannino, B Miller, R Tal-Singer, DA Lomas Thorax 68 (7), 670-676, 2013 | 288 | 2013 |
| COPD association and repeatability of blood biomarkers in the ECLIPSE cohort JA Dickens, BE Miller, LD Edwards, EK Silverman, DA Lomas, ... Respiratory research 12, 1-10, 2011 | 226 | 2011 |
| The molecular and cellular pathology of α1-antitrypsin deficiency B Gooptu, JA Dickens, DA Lomas Trends in molecular medicine 20 (2), 116-127, 2014 | 127 | 2014 |
| Circulating polymers in α1-antitrypsin deficiency L Tan, JA Dickens, DL DeMeo, E Miranda, J Perez, ST Rashid, J Day, ... European Respiratory Journal 43 (5), 1501-1504, 2014 | 82 | 2014 |
| Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis JA Dickens, DA Lomas Drug design, development and therapy, 391-405, 2011 | 68 | 2011 |
| A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity A Ordóñez, J Pérez, L Tan, JA Dickens, N Motamedi-Shad, JA Irving, ... The FASEB Journal 29 (6), 2667, 2015 | 58 | 2015 |
| Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin EFA van ‘t Wout, JA Dickens, A van Schadewijk, I Haq, HF Kwok, ... Human Molecular Genetics 23 (4), 929-941, 2014 | 42 | 2014 |
| Pulmonary endoplasmic reticulum stress—scars, smoke, and suffocation JA Dickens, E Malzer, JE Chambers, SJ Marciniak The FEBS journal 286 (2), 322-341, 2019 | 33 | 2019 |
| The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin JA Dickens, A Ordóñez, JE Chambers, AJ Beckett, V Patel, E Malzer, ... The FASEB Journal 30 (12), 4083, 2016 | 32 | 2016 |
| Altered native stability is the dominant basis for susceptibility of α1-antitrypsin mutants to polymerization JA Irving, I Haq, JA Dickens, SV Faull, DA Lomas Biochemical Journal 460 (1), 103-119, 2014 | 31 | 2014 |
| New concepts in alpha-1 antitrypsin deficiency disease mechanisms SJ Marciniak, A Ordóñez, JA Dickens, JE Chambers, V Patel, ... Annals of the American Thoracic Society 13 (Supplement 4), S289-S296, 2016 | 30 | 2016 |
| Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway I Haq, JA Irving, SV Faull, JA Dickens, A Ordóñez, D Belorgey, B Gooptu, ... Bioscience Reports 33 (3), e00046, 2013 | 29 | 2013 |
| Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody L Tan, J Perez, M Mela, E Miranda, KA Burling, FN Rouhani, DL DeMeo, ... The international journal of biochemistry & cell biology 58, 81-91, 2015 | 26 | 2015 |
| Z-α1-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state JE Chambers, N Zubkov, M Kubánková, J Nixon-Abell, I Mela, S Abreu, ... Science Advances 8 (14), eabm2094, 2022 | 24 | 2022 |
| The integrated stress response regulates BMP signalling through effects on translation E Malzer, CS Dominicus, JE Chambers, JA Dickens, S Mookerjee, ... BMC biology 16, 1-15, 2018 | 22 | 2018 |
| Evaluation of COPD Longitudinally to Identify Surrogate Endpoints (ECLIPSE) study investigators. COPD association and repeatability of blood biomarkers in the ECLIPSE cohort JA Dickens, BE Miller, LD Edwards, EK Silverman, DA Lomas, ... Respir Res 12 (1), 146-155, 2011 | 21 | 2011 |
| Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant JA Dickens, EN Rutherford, S Abreu, JE Chambers, MO Ellis, ... European Respiratory Journal 59 (1), 2022 | 20 | 2022 |
| CC-16 as a biomarker in chronic obstructive pulmonary disease JA Dickens, DA Lomas COPD: Journal of Chronic Obstructive Pulmonary Disease 9 (5), 574-575, 2012 | 14 | 2012 |
| Brief report: A Novel sodium/iodide symporter mutation, S356F, causing congenital hypothyroidism H Durgia, AK Nicholas, E Schoenmakers, JA Dickens, D Halanaik, ... Thyroid 32 (2), 215-218, 2022 | 4 | 2022 |
| Measuring the effects of α1‐antitrypsin polymerisation on the structure and biophysical properties of the endoplasmic reticulum JE Chambers, JA Dickens, SJ Marciniak Biology of the Cell 110 (11), 249-255, 2018 | 4 | 2018 |
