Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Z Wang, E Klipfell, BJ Bennett, R Koeth, BS Levison, B DuGar, ... nature 472 (7341), 57-63, 2011 | 5935 | 2011 |
Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis RA Koeth, Z Wang, BS Levison, JA Buffa, E Org, BT Sheehy, EB Britt, X Fu, ... Nature medicine 19 (5), 576-585, 2013 | 4850 | 2013 |
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells AS Plump, JD Smith, T Hayek, K Aalto-Setälä, A Walsh, JG Verstuyft, ... Cell 71 (2), 343-353, 1992 | 2921 | 1992 |
Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice M Febbraio, EA Podrez, JD Smith, DP Hajjar, SL Hazen, HF Hoff, ... The Journal of clinical investigation 105 (8), 1049-1056, 2000 | 1374 | 2000 |
Apolipoprotein E allele–specific antioxidant activity and effects on cytotoxicity by oxidative insults and β–amyloid peptides M Miyata, JD Smith Nature genetics 14 (1), 55-61, 1996 | 1170 | 1996 |
ApoE promotes the proteolytic degradation of Aβ Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ... Neuron 58 (5), 681-693, 2008 | 1161 | 2008 |
Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. JD Smith, E Trogan, M Ginsberg, C Grigaux, J Tian, M Miyata Proceedings of the National Academy of Sciences 92 (18), 8264-8268, 1995 | 1064 | 1995 |
Apolipoprotein AI is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease L Zheng, B Nukuna, ML Brennan, M Sun, M Goormastic, M Settle, ... The Journal of clinical investigation 114 (4), 529-541, 2004 | 938 | 2004 |
Meta-analysis identifies six new susceptibility loci for atrial fibrillation PT Ellinor, KL Lunetta, CM Albert, NL Glazer, MD Ritchie, AV Smith, ... Nature genetics 44 (6), 670-675, 2012 | 714 | 2012 |
Multi-ethnic genome-wide association study for atrial fibrillation C Roselli, MD Chaffin, LC Weng, S Aeschbacher, G Ahlberg, CM Albert, ... Nature genetics 50 (9), 1225-1233, 2018 | 701 | 2018 |
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO RA Koeth, BS Levison, MK Culley, JA Buffa, Z Wang, JC Gregory, E Org, ... Cell metabolism 20 (5), 799-812, 2014 | 575 | 2014 |
Common variants in KCNN3 are associated with lone atrial fibrillation PT Ellinor, KL Lunetta, NL Glazer, A Pfeufer, A Alonso, MK Chung, ... Nature genetics 42 (3), 240-244, 2010 | 566 | 2010 |
Genome-wide association study of PR interval A Pfeufer, C Van Noord, KD Marciante, DE Arking, MG Larson, AV Smith, ... Nature genetics 42 (2), 153-159, 2010 | 511 | 2010 |
High-density lipoprotein function, dysfunction, and reverse cholesterol transport EA Fisher, JE Feig, B Hewing, SL Hazen, JD Smith Arteriosclerosis, thrombosis, and vascular biology 32 (12), 2813-2820, 2012 | 472 | 2012 |
T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse HM Dansky, SA Charlton, MMG Harper, JD Smith Proceedings of the National Academy of Sciences 94 (9), 4642-4646, 1997 | 421 | 1997 |
An abundant dysfunctional apolipoprotein A1 in human atheroma Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li, Y Wu, J Buffa, T Kim, ... Nature medicine 20 (2), 193-203, 2014 | 414 | 2014 |
Alcohol consumption raises HDL cholesterol levels by increasing the transport rate of apolipoproteins AI and A-II ER De Oliveira e Silva, D Foster, M McGee Harper, CE Seidman, ... Circulation 102 (19), 2347-2352, 2000 | 402 | 2000 |
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides T Tokuda, M CALERO, E MATSUBARA, R VIDAL, A KUMAR, ... Biochemical Journal 348 (2), 359-365, 2000 | 365 | 2000 |
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation IE Christophersen, M Rienstra, C Roselli, X Yin, B Geelhoed, J Barnard, ... Nature genetics 49 (6), 946-952, 2017 | 352 | 2017 |
HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation S Galvani, M Sanson, VA Blaho, SL Swendeman, H Obinata, H Conger, ... Science signaling 8 (389), ra79-ra79, 2015 | 342 | 2015 |