A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties JM Murphy, Q Zhang, SN Young, ML Reese, FP Bailey, PA Eyers, ... Biochemical Journal 457 (2), 323-334, 2014 | 286 | 2014 |
The hVps34‐SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth R Bago, E Sommer, P Castel, C Crafter, FP Bailey, N Shpiro, J Baselga, ... The EMBO journal 35 (17), 1902-1922, 2016 | 108 | 2016 |
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner FP Bailey, DP Byrne, K Oruganty, CE Eyers, CJ Novotny, KM Shokat, ... Biochemical Journal 467 (1), 47-62, 2015 | 94 | 2015 |
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells DM Foulkes, DP Byrne, W Yeung, S Shrestha, FP Bailey, S Ferries, ... Sci. Signal. 11 (549), eaat7951, 2018 | 79 | 2018 |
Going for broke: targeting the human cancer pseudokinome FP Bailey, DP Byrne, D McSkimming, N Kannan, PA Eyers Biochemical Journal 465 (2), 195-211, 2015 | 35 | 2015 |
Tribbles pseudokinases: novel targets for chemical biology and drug discovery? DM Foulkes, DP Byrne, FP Bailey, PA Eyers Biochemical Society Transactions 43 (5), 1095-1103, 2015 | 31 | 2015 |
Adaptation of the human Cell Line Activation Test (h-CLAT) to Animal-Product-Free Conditions. A Edwards, L Roscoe, C Longmore, F Bailey, B Sim, C Treasure ALTEX, 2018 | 19 | 2018 |
The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles FP Bailey, VI Andreev, PA Eyers Methods in enzymology 548, 117-146, 2014 | 18 | 2014 |
Kinome‐wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics FP Bailey, K Clarke, H Kalirai, J Kenyani, H Shahidipour, F Falciani, ... Pigment cell & melanoma research 31 (2), 253-266, 2018 | 16 | 2018 |
Towards 20, 20-difluorinated bryostatin: synthesis and biological evaluation of difluorinated C17, C27-fragments EJ Thomas, PR Mears, S Hoekman, C Rye, F Bailey, D Byrne, PA Eyers Organic & Biomolecular Chemistry, 2019 | 10 | 2019 |
Repurposing covalent EGFR/HER2 inhibitors for on-target degradation of human Tribbles 2 (TRIB2) pseudokinase DM Foulkes, DP Byrne, FP Bailey, S Ferries, C Eyers, K Keeshan, ... bioRxiv, 305243, 2018 | 2 | 2018 |
2) Going for broke: targeting the human cancer pseudokinome FP Bailey, DP Byrne, D McSkimming, N Kannan, PA Eyers Biochemical Journal 466 (1), 201-201, 2015 | 1 | 2015 |
The response of uveal melanoma (UM) cells to Bromodomain and Extra Terminal (BET) inhibitors FP Bailey, H Kalirai, H Shahidipour, K Clarke, SE Coupland, PA Eyers Investigative Ophthalmology & Visual Science 58 (8), 566-566, 2017 | | 2017 |
Biochemical Journal www. biochemj. org JM MURPHY, Q ZHANG, SN YOUNG, ML REESE, FP BAILEY, ... Biochem. J 457, 323-334, 2014 | | 2014 |
Biochemical Analysis of Human Cancer-Associated Pseudokinases F Bailey University of Sheffield, 2014 | | 2014 |